Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G003153`

染色体: Chr02 坐标: 52573268-52575707 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G003153`
名称	SmilChr02G003153
描述	beta-amyrin 6-beta-monooxygenase-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	52573268 - 52575707 / `-`

ID 对照

NCBI Gene ID	`LOC131010148`
GeneID	`131010148`
locus_tag	`-`
NCBI Name	`LOC131010148`
原始查询	`LOC131010148`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	beta-amyrin 6-beta-monooxygenase-like
产物	beta-amyrin 6-beta-monooxygenase-like
Arabidopsis	`AT5G36110` (CYP716A1) cytochrome P450, family 716, subfamily A, polypeptide 1 [Source:NCBI gene (formerly Entrezgene);Acc:833607] identity=50; qcov=0.952; evalue=6.31e-152; confidence=high
Rice	`Os07g0518500` (OSJNBa0036M16.135-2) - identity=35.7; qcov=1.02; evalue=9.35e-94; confidence=medium
GO	GO:0004497 (monooxygenase activity); GO:0005506 (iron ion binding); GO:0016125 (sterol metabolic process); GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen); GO:0020037 (heme binding)
KEGG	smil00999 (Biosynthesis of various plant secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00067 (p450)
InterPro	-
eggNOG	-
NR	GeneID:131010148

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057793546.1`
2	Endoplasmic reticulum membrane	内质网膜	0.80000	`XP_057793546.1`
3	Nucleus	细胞核	0.00000	`XP_057793546.1`
4	Chromosome	染色体	0.00000	`XP_057793546.1`
5	Centromere	着丝粒	0.00000	`XP_057793546.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:52573368`	`GA`	`G`	1bp_deletion	frameshift_variant	9	A23,B101,B109,B123,B130,B136,B46,C71,C82
`Chr2:52573408`	`A`	`AC`	1bp_insertion	frameshift_variant	116	A1,A10,A11,A13,A14,A19,A2,A20,A21,A23,A24,A4,A7,A9,B10,B101,B103,B108,B109,B110,B113,B117,B12,B121,B123,B125,B126,B129,B13,B130,B131,B135,B136,B139,B15,B17,B18,B21,B22,B23,B24,B28,B3,B30,B31,B33,B45,B46,B48,B50,B52,B56,B57,B63,B64,B65,B66,B68,B7,B71,B78,B8,B80,B83,B84,B86,B88,B9,B91,B94,B95,B96,B98,C1,C13,C14,C15,C16,C19,C24,C28,C30,C4,C40,C41,C44,C48,C49,C5,C53,C55,C57,C59,C60,C61,C62,C64,C66,C67,C70,C71,C72,C73,C76,C77,C78,C81,C82,C83,C85,C86,C87,D1,D2,D5,D7
`Chr2:52573409`	`T`	`TTC`	2bp_insertion	frameshift_variant	116	A1,A10,A11,A13,A14,A19,A2,A20,A21,A23,A24,A4,A7,A9,B10,B101,B103,B108,B109,B110,B113,B117,B12,B121,B123,B125,B126,B129,B13,B130,B131,B135,B136,B139,B15,B17,B18,B21,B22,B23,B24,B28,B3,B30,B31,B33,B45,B46,B48,B50,B52,B56,B57,B63,B64,B65,B66,B68,B7,B71,B78,B8,B80,B83,B84,B86,B88,B9,B91,B94,B95,B96,B98,C1,C13,C14,C15,C16,C19,C24,C28,C30,C4,C40,C41,C44,C48,C49,C5,C53,C55,C57,C59,C60,C61,C62,C64,C66,C67,C70,C71,C72,C73,C76,C77,C78,C81,C82,C83,C85,C86,C87,D1,D2,D5,D7
`Chr2:52573492`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C48,D7
`Chr2:52573625`	`TG`	`T`	1bp_deletion	frameshift_variant	19	A1,A13,A4,B11,B117,B131,B132,B49,B56,B63,B64,B83,B9,C27,C3,C44,C53,C67,C76
`Chr2:52573627`	`GGA`	`G`	2bp_deletion	frameshift_variant	1	D11
`Chr2:52573627`	`GGA`	`G`	2bp_deletion	CDS_variant	1	D11
`Chr2:52573787`	`A`	`AG`	1bp_insertion	frameshift_variant	1	C54
`Chr2:52573787`	`A`	`AG`	1bp_insertion	CDS_variant	1	C54
`Chr2:52573799`	`C`	`CAA`	2bp_insertion	frameshift_variant	1	B65
`Chr2:52573799`	`C`	`CAA`	2bp_insertion	CDS_variant	1	B65
`Chr2:52573843`	`GCA`	`G`	2bp_deletion	frameshift_variant	2	C75,D1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057793546.1

477 aa

238

477

p450

PF00067 p450 38-449 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057793546.1`	Pfam	`PF00067`	p450	Domain	38	449	1.8e-55	189.3	Cytochrome P450

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057937563.1
GTAGAGTTGAACGTTGAAATTTTACTTAATTAAAACTACCAATTTTCTATTTTGTTTTGTTAAGATGAATTTTGTGGTTCATCCTAGTTCAATAGCTGTTTGCTAATCTAACCGCATCAGTTTCTGACTATCGTATTTCTTCCAACTCTCTCTCTCGTGGCTATTGGTGTCGGTCTTATAAGGATTCCTTTTGACTTAATTAAATTCAAAATTTAACTTGTTTAGCATCCACTATTATTTAATGAAGCTTTTTTAGTCCT...

CDS

1 records

下载 CDS FASTA

LOC131010148
ATGGAGGCCTTAACATTTCCTTCGTATCTTCTCCCTCTTCTCCTTCTGCCTTTCTCTCTCTATCTCTTCTCGATCATCCGGAGAAAGAGCTCCGATGATCGGAAAAACCTCCCTCCCGGCTCCCGGGGCTGGCCGGTTGTCGGAGAGAACATCAAGTTCGCCCTCTTAGGCCCCGAGAAATTCATCAAAGATAGAATGGAGAAACACTCTCCCGAGGTATTCCAAACTTCGTTGTTGGGAGAGAGAGTGGCCACATTCTG...

Protein

1 records

下载 Protein FASTA

XP_057793546.1
MEALTFPSYLLPLLLLPFSLYLFSIIRRKSSDDRKNLPPGSRGWPVVGENIKFALLGPEKFIKDRMEKHSPEVFQTSLLGERVATFCGAKGNKFLFTNGNKLVTSWWPQSMKKVLSFPEFVDSNLKVDSALKRTLHRDVFTPEALKRHVAVMDALAREHLERHWKPNSVVKVLGLSRKYTFELACRVFLSEVDPVRIQKLSDPFNMVSEGMISVPLDLPGTAYNRAIKGGKLVREELMRIIQERRKELMEKPERRDLLSK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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