Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G003217`

染色体: Chr02 坐标: 53338939-53349356 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G003217`
名称	SmilChr02G003217
描述	DEAD-box ATP-dependent RNA helicase FANCM
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	53338939 - 53349356 / `+`

ID 对照

NCBI Gene ID	`LOC131010203`
GeneID	`131010203`
locus_tag	`-`
NCBI Name	`LOC131010203`
原始查询	`LOC131010203`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DEAD-box ATP-dependent RNA helicase FANCM
产物	DEAD-box ATP-dependent RNA helicase FANCM
Arabidopsis	`AT1G35530` (FANCM) DEAD/DEAH box RNA helicase family protein [Source:NCBI gene (formerly Entrezgene);Acc:840448] identity=51.1; qcov=1.03; evalue=0; confidence=high
Rice	`Os11g0180600` - identity=59.1; qcov=0.239; evalue=3.18e-106; confidence=weak
GO	GO:0000400 (four-way junction DNA binding); GO:0005524 (ATP binding); GO:0009378 (four-way junction helicase activity); GO:0016787 (hydrolase activity); GO:0036297 (interstrand cross-link repair); GO:0043138 (3'-5' DNA helicase activity); GO:0045003 (double-strand break repair via synthesis-dependent strand annealing); GO:0071932 (replication fork reversal)
KEGG	smil03460 (Fanconi anemia pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF00270 (DEAD); PF00271 (Helicase_C); PF04851 (ResIII)
InterPro	-
eggNOG	-
NR	GeneID:131010203

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057793600.1`
2	Nucleoplasm	核质	0.80000	`XP_057793602.1`
3	Nuclear body	核内小体	0.60000	`XP_057793602.1`
4	Chromosome	染色体	0.20000	`XP_057793600.1`
5	PML body	PML body	0.20000	`XP_057793600.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:53339595`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A5,D9
`Chr2:53340294`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C62
`Chr2:53341182`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B126,B34,B61,C17,C21
`Chr2:53341877`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B1,B100
`Chr2:53343651`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A23
`Chr2:53344809`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A7
`Chr2:53344811`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A2,B107,B18,B34,B80
`Chr2:53345578`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A2,B126,B83,C62
`Chr2:53346006`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A2,B122,C60,C61
`Chr2:53346117`	`TTG`	`T`	2bp_deletion	frameshift_variant	3	A25,B137,C18
`Chr2:53346117`	`TTG`	`T`	2bp_deletion	CDS_variant	3	A25,B137,C18
`Chr2:53346191`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C40

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057793600.1

1367 aa

684

1367

ResIII

DEAD

Helicase_C

PF04851 ResIII 143-300 aa PF00270 DEAD 147-304 aa PF00271 Helicase_C 482-599 aa

XP_057793601.1

1363 aa

682

1363

ResIII

DEAD

Helicase_C

PF04851 ResIII 143-300 aa PF00270 DEAD 147-304 aa PF00271 Helicase_C 482-599 aa

XP_057793602.1

1220 aa

610

1220

ResIII

DEAD

Helicase_C

PF04851 ResIII 11-153 aa PF00270 DEAD 11-157 aa PF00271 Helicase_C 335-452 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057793600.1`	Pfam	`PF04851`	ResIII	Family	143	300	4e-19	69.8	Type III restriction enzyme, res subunit
`XP_057793600.1`	Pfam	`PF00270`	DEAD	Domain	147	304	2.1e-21	77.1	DEAD/DEAH box helicase
`XP_057793600.1`	Pfam	`PF00271`	Helicase_C	Domain	482	599	1.4e-20	74.3	Helicase conserved C-terminal domain
`XP_057793601.1`	Pfam	`PF04851`	ResIII	Family	143	300	2.7e-19	70.4	Type III restriction enzyme, res subunit
`XP_057793601.1`	Pfam	`PF00270`	DEAD	Domain	147	304	2.1e-21	77.1	DEAD/DEAH box helicase
`XP_057793601.1`	Pfam	`PF00271`	Helicase_C	Domain	482	599	1.2e-20	74.5	Helicase conserved C-terminal domain
`XP_057793602.1`	Pfam	`PF04851`	ResIII	Family	11	153	1.4e-18	68.1	Type III restriction enzyme, res subunit
`XP_057793602.1`	Pfam	`PF00270`	DEAD	Domain	11	157	4.5e-21	76.0	DEAD/DEAH box helicase
`XP_057793602.1`	Pfam	`PF00271`	Helicase_C	Domain	335	452	1.1e-20	74.7	Helicase conserved C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057937618.1
GAACCATGTCTATTTACGAATACGAGCTTGGCTCTCACCACCAACAGTTGCAAATTCAAAAATAAATAAAATAAAGAAAATTGCCGCTAATTCTCCATCCAACTTGAGGTTTTCTGCTCATCTCTCTCTTCCAATTCCCAAACAGGCAAACACCCACTATTAAATTAAACACTGGTTTGTTTACCAAGAGCTCTTATGGTTTCCGCATCCGCTCCTCTTCAAATCATGGACGACGACGATGAATTCGACTGGGAAGCAGC...

XM_057937617.1
AACCATGTCTATTTACGAATACGAGCTTGGCTCTCACCACCAACAGTTGCAAATTCAAAAATAAATAAAATAAAGAAAATTGCCGCTAATTCTCCATCCAACTTGAGGTTTTCTGCTCATCTCTCTCTTCCAATTCCCAAACAGGCAAACACCCACTATTAAATTAAACACTGGTTTGTTTACCAAGAGCTCTTATGGTTTCCGCATCCGCTCCTCTTCAAATCATGGACGACGACGATGAATTCGACTGGGAAGCAGCT...

CDS

3 records

下载 CDS FASTA

LOC131010203
ATGGTTTCCGCATCCGCTCCTCTTCAAATCATGGACGACGACGATGAATTCGACTGGGAAGCAGCTGTTCATGAAATCGATGTGGCGTGCCGGGCAACTGCTGCTGAAATGCCCACAGTCGTTCCTGATTCAAACTGCAAACAAGAGATGTTTGTGAACACAGATCAAGCAATGCGGAAAAAGGGGAAATTTGAGGCTAATCTTAGTTCAGCTCCTTCAACTAGGCAAACTACTTTAGATAAATTTATTGGGGTTTCGTC...

Protein

3 records

下载 Protein FASTA

XP_057793600.1
MVSASAPLQIMDDDDEFDWEAAVHEIDVACRATAAEMPTVVPDSNCKQEMFVNTDQAMRKKGKFEANLSSAPSTRQTTLDKFIGVSSCNSRKFEEKAGNSYGQLCMSNSIGNNICEETEKLNEFVSIDAEAAKTWIYPVNIPCRDYQLSITRTALFANTLVALPTGLGKTLIAAVVMYNFFRWFPEGKIVFAAPSRPLVMQQIEACHKIVGIPQEWTIDLTGQTSPSKRAEFWKCKRVFFVTPQVLEKDIQSGSCLVKNL...

XP_057793601.1
MVSASAPLQIMDDDDEFDWEAAVHEIDVACRATAAEMPTVVPDSNCKQEMFVNTDQAMRKKGKFEANLSSAPSTRQTTLDKFIGVSSCNSRKFEEKAGNSYGQLCMSNSIGNNICEETEKLNEFVSIDAEAAKTWIYPVNIPCRDYQLSITRTALFANTLVALPTGLGKTLIAAVVMYNFFRWFPEGKIVFAAPSRPLVMQQIEACHKIVGIPQEWTIDLTGQTSPSKRAEFWKCKRVFFVTPQVLEKDIQSGSCLVKNL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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