Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004046`

染色体: Chr02 坐标: 62762925-62773201 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004046`
名称	SmilChr02G004046
描述	uncharacterized SmilChr02G004046
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	62762925 - 62773201 / `-`

ID 对照

NCBI Gene ID	`LOC131010979`
GeneID	`131010979`
locus_tag	`-`
NCBI Name	`LOC131010979`
原始查询	`LOC131010979`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	Patched family protein [Source:NCBI gene (formerly Entrezgene);Acc:840851]; symbol=AT1G42470; hit=AT1G42470; species=arabidopsis; confidence=high
产物	Patched family protein [Source:NCBI gene (formerly Entrezgene);Acc:840851]; symbol=AT1G42470; hit=AT1G42470; species=arabidopsis; confidence=high
Arabidopsis	`AT1G42470` (AT1G42470) Patched family protein [Source:NCBI gene (formerly Entrezgene);Acc:840851] identity=75; qcov=0.964; evalue=0; confidence=high
Rice	`Os04g0563801` - identity=69.3; qcov=0.685; evalue=0; confidence=high
GO	GO:0005319 (lipid carrier activity); GO:0016020 (membrane)
KEGG	smil04142 (Lysosome biogenesis - Salvia miltiorrhiza (redroot sage))
Pfam	PF02460 (Patched); PF12349 (Sterol-sensing); PF16414 (NPC1_N); PF22314 (NPC1_MLD)
InterPro	-
eggNOG	-
NR	GeneID:131010979

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Vacuole	液泡	0.60000	`XP_057794684.1`
2	Vacuole membrane	液泡膜	0.60000	`XP_057794684.1`
3	Cell membrane	细胞膜	0.40000	`XP_057794684.1`
4	Cytoplasmic vesicle	细胞质囊泡	0.20000	`XP_057794684.1`
5	Nucleus	细胞核	0.00000	`XP_057794684.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:62763287`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	D11,D7
`Chr2:62763313`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	B55
`Chr2:62763313`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B55
`Chr2:62763335`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr2:62763696`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A18,A24,B82,C12
`Chr2:62763790`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B108,B50,C23
`Chr2:62764453`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B18,B91
`Chr2:62764980`	`GGT`	`G`	2bp_deletion	frameshift_variant	1	B77
`Chr2:62764980`	`GGT`	`G`	2bp_deletion	CDS_variant	1	B77
`Chr2:62766511`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C71
`Chr2:62767012`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr2:62767194`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C79,D10

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057794684.1

1294 aa

647

1294

NPC1_N

NPC1_MLD

Patched

Sterol-sensing

PF16414 NPC1_N 48-282 aa PF22314 NPC1_MLD 424-615 aa PF02460 Patched 638-791 aa PF12349 Sterol-sensing 659-809 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057794684.1`	Pfam	`PF16414`	NPC1_N	Domain	48	282	7.9e-67	226.2	Niemann-Pick C1 N terminus
`XP_057794684.1`	Pfam	`PF22314`	NPC1_MLD	Domain	424	615	2e-37	129.8	NPC1, middle luminal domain
`XP_057794684.1`	Pfam	`PF02460`	Patched	Domain	638	791	3e-31	109.0	Patched SSD
`XP_057794684.1`	Pfam	`PF12349`	Sterol-sensing	Family	659	809	1.3e-46	158.9	Sterol-sensing domain of SREBP cleavage-activation

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057938701.1
CACTCTGTAGTCTGAACACTCCCCCCTCACTCCCTCTCTCTCTCTCTACACGTCTCTGCACATTTATATATATATACTAACTCTCCCGTATTCCTGTGGTGATGGTGCCACACCATTTATGATGATCAACCATTCTCTGCATTGACTCCAAACTATTTCTCCTCTTAAATTGAGAGCTCCAATTCTCTCTCTCTCTCTCTACTGTGATTGAATTCCGGCTTTGATTGGAGCTCCATTTCTGCTGCAATGGAGGGGGAGAG...

CDS

1 records

下载 CDS FASTA

LOC131010979
ATGGAGGGGGAGAGTATGAGGGGACTCCGGCGTCTGCTGGCGTTCACGGTGTTGTTTGTGGCGGCTGTGGTGGATTCGGAGCGGCCTGATGCGAGGCTTCTTTTGACGGATAATGCCGGTGGCGGACAGAGCCACTCGGAGGAATACTGTGCTATGTACGACATTTGTGGAGCTCGTAGTGATGGCAAAGTGCTGAATTGCCCTGTTGGCATCCCTGCAGTCAAGCCCGATGAATTGTTATCAGCAAAAATTCAGAGCTT...

Protein

1 records

下载 Protein FASTA

XP_057794684.1
MEGESMRGLRRLLAFTVLFVAAVVDSERPDARLLLTDNAGGGQSHSEEYCAMYDICGARSDGKVLNCPVGIPAVKPDELLSAKIQSLCPTITGNVCCTEAQFNTLRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSQFINVTSIAKVGNNSTVNGIDYYITDSFGSGLYESCKDVKFGTMNTRAMEFIGAGAKNFREWYAFIGRRAGLGIPGSPFAINFLPAAPESMGMTPMNVSTYSCGDTSLGCSCGDCPSSAA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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