Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G002762`

染色体: Chr02 坐标: 47680166-47685536 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G002762`
名称	SmilChr02G002762
描述	2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	47680166 - 47685536 / `-`

ID 对照

NCBI Gene ID	`LOC131011792`
GeneID	`131011792`
locus_tag	`-`
NCBI Name	`LOC131011792`
原始查询	`LOC131011792`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial-like
产物	2-oxoisovalerate dehydrogenase subunit alpha 2%2C mitochondrial-like
Arabidopsis	`AT5G09300` (AT5G09300) thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:830789] identity=70.4; qcov=0.919; evalue=0; confidence=high
Rice	`Os12g0183100` - identity=68.9; qcov=0.914; evalue=0; confidence=high
GO	GO:0005947 (GO:0005947); GO:0009083 (branched-chain amino acid catabolic process); GO:0016624 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00676 (E1_dh); PF13292 (DXP_synthase_N)
InterPro	-
eggNOG	-
NR	GeneID:131011792

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057795616.1`
2	Cytoplasm	细胞质	0.60000	`XP_057795617.1`
3	Mitochondrion matrix	线粒体基质	0.40000	`XP_057795616.1`
4	Cytosol	细胞质基质	0.40000	`XP_057795617.1`
5	Nucleus	细胞核	0.20000	`XP_057795617.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:47680831`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:47680858`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A23,B21,B51,D3
`Chr2:47681256`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C53
`Chr2:47681307`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A21,A25,B113,B50,C18
`Chr2:47681522`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A24,C78
`Chr2:47681630`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B32
`Chr2:47681839`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B93,C2
`Chr2:47681866`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B94
`Chr2:47684717`	`T`	`TG`	1bp_insertion	frameshift_variant	5	B103,B127,B53,C16,C85
`Chr2:47684717`	`T`	`TG`	1bp_insertion	CDS_variant	5	B103,B127,B53,C16,C85
`Chr2:47684723`	`A`	`AC`	1bp_insertion	frameshift_variant	45	A10,A24,A4,A5,A6,A8,B1,B10,B108,B118,B124,B132,B15,B19,B20,B22,B32,B35,B4,B46,B5,B6,B62,B63,B75,B81,B83,B86,B99,C10,C25,C27,C28,C30,C35,C37,C40,C43,C63,C72,C75,C76,C82,D4,D9
`Chr2:47684760`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C51

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795616.1

472 aa

236

472

E1_dh

DXP_synthase_N

PF00676 E1_dh 133-430 aa PF13292 DXP_synthase_N 237-302 aa

XP_057795617.1

408 aa

204

408

E1_dh

DXP_synthase_N

PF00676 E1_dh 69-366 aa PF13292 DXP_synthase_N 173-238 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795616.1`	Pfam	`PF00676`	E1_dh	Domain	133	430	6.4e-97	324.9	Dehydrogenase E1 component
`XP_057795616.1`	Pfam	`PF13292`	DXP_synthase_N	Family	237	302	5.7e-06	26.5	1-deoxy-D-xylulose-5-phosphate synthase
`XP_057795617.1`	Pfam	`PF00676`	E1_dh	Domain	69	366	4.2e-97	325.5	Dehydrogenase E1 component
`XP_057795617.1`	Pfam	`PF13292`	DXP_synthase_N	Family	173	238	4.7e-06	26.8	1-deoxy-D-xylulose-5-phosphate synthase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057939633.1
TATTTATTTATAATTAATTTTTTGCACCCTATTTATTTATAATTACTTTAAGCGTCAAATAATCCGTGTCCCATATTCAACAATTATTAATCACATCGAACATCACATGTAAATGTAACTCATTTATTTATTTATTTATTTAAAGAGGGGAGGATAGGCTAGCCATTTCGGTAGAGTTTGGCGCGCACACACACTTCTCTCTCTCCATTAAATTCAAGTCCAACAAATACTTTGTTTCTCCTAGACAGCACTGTGCATTG...

XM_057939634.1
AGCCATTTCGGTAGAGTTTGGCGCGCACACACACTTCTCTCTCTCCATTAAATTCAAGTCCAACAAATACTTTGTTTCTCCTAGACAGCACTGTGCATTGAATTTATTATACATACGGTACAGGGTCCTATATCACATGTTATAACTTATATAACACACACACACACACACACACTAGTGAGATTCTTGGAAAATATGGGGTCATGGTTTGGAAGATCAAGAAGCATCCCATATTTGCTCAAGAGAAACATTTCTTCCTT...

CDS

2 records

下载 CDS FASTA

LOC131011792
ATGGGGTCATGGTTTGGAAGATCAAGAAGCATCCCATATTTGCTCAAGAGAAACATTTCTTCCTTTGACAAGAGGTGTTCATCAACTCATTCTTTCTTACTTGCAAATTCTTCTTACAAAAGCCCTCATGGATTCTCTATTTTGTCGTTCCGCCGGTCGGAATCCGCCATGGCCGGAAAACAAGCTCAAGCTGTAGCTTACACCGATGATGATGTTGATGATGAAAACCAGAGCATAGAGTTTCCTGGTGGAAGGGTTGG...

LOC131011792
ATGTATATCCATAAACGGAGAAGCAATAAAGAAATAATAGGGGGGTCCATTACGAAAAGAAGGAAAATAGATGGAAGAAATCAAAATGAGCATTGCGAAGCCACTGAGAACAGAGTTGCCTGTTATCGCGTTCTCGACGATCATGGCTATCCCATTGCAGGCACTACATTTGACCAGGTGGATGAAGAAACGGCAGTGAGGATGTACAAAAGCATGGCGAGCCTTGAAATAATGGATAGCATCTTCTATGAAGCGCAACG...

Protein

2 records

下载 Protein FASTA

XP_057795616.1
MGSWFGRSRSIPYLLKRNISSFDKRCSSTHSFLLANSSYKSPHGFSILSFRRSESAMAGKQAQAVAYTDDDVDDENQSIEFPGGRVGLTTQMKFISEATENRVACYRVLDDHGYPIAGTTFDQVDEETAVRMYKSMASLEIMDSIFYEAQRQGRVSFYLTSTGEEGISVATAAALSPHDIILPQYREAGILLWRGFTIQDFANQCFGNEDDHGKGRQMPVHYGSNHLNFFTVSSPIATQLPQAAGVAYSLKMDGKDACAV...

XP_057795617.1
MYIHKRRSNKEIIGGSITKRRKIDGRNQNEHCEATENRVACYRVLDDHGYPIAGTTFDQVDEETAVRMYKSMASLEIMDSIFYEAQRQGRVSFYLTSTGEEGISVATAAALSPHDIILPQYREAGILLWRGFTIQDFANQCFGNEDDHGKGRQMPVHYGSNHLNFFTVSSPIATQLPQAAGVAYSLKMDGKDACAVAFTGDGATSEGDFHAAMNFAAVMEAPVLFICRNNGWAISTPISQQFRSDGVVVKGQAYGIRSIR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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