Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G001801`

染色体: Chr02 坐标: 32868485-32872429 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G001801`
名称	SmilChr02G001801
描述	malate dehydrogenase, mitochondrial-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	32868485 - 32872429 / `+`

ID 对照

NCBI Gene ID	`LOC131012052`
GeneID	`131012052`
locus_tag	`-`
NCBI Name	`LOC131012052`
原始查询	`LOC131012052`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	malate dehydrogenase, mitochondrial-like
产物	malate dehydrogenase%2C mitochondrial-like
Arabidopsis	`AT1G53240` (mMDH1) Lactate/malate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:841757] identity=81.2; qcov=0.746; evalue=0; confidence=high
Rice	`Os01g0649100` (OsmMDH) - identity=83.7; qcov=0.739; evalue=0; confidence=high
GO	GO:0000104 (succinate dehydrogenase activity); GO:0005737 (cytoplasm); GO:0005739 (mitochondrion); GO:0006099 (tricarboxylic acid cycle); GO:0006108 (malate metabolic process); GO:0009055 (electron transfer activity); GO:0016020 (membrane); GO:0030060 (L-malate dehydrogenase (NAD+) activity); GO:0045281 (GO:0045281)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00566 (Sulfoquinovose metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00710 (Carbon fixation by Calvin cycle - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00056 (Ldh_1_N); PF01127 (Sdh_cyt); PF02866 (Ldh_1_C)
InterPro	-
eggNOG	-
NR	GeneID:131012052

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057795938.1`
2	Mitochondrion membrane	线粒体膜	1.00000	`XP_057795938.1`
3	Mitochondrion inner membrane	线粒体内膜	0.80000	`XP_057795938.1`
4	Nucleus	细胞核	0.00000	`XP_057795938.1`
5	Chromosome	染色体	0.00000	`XP_057795938.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:32868627`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B91
`Chr2:32868772`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B103,C1,C49
`Chr2:32868845`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A16,B1,B91,C30
`Chr2:32869974`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr2:32870662`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D4
`Chr2:32871880`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B72,B93
`Chr2:32871955`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A16,B1,C30

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795938.1

456 aa

228

456

Ldh_1_N

Ldh_1_C

Sdh_cyt

PF00056 Ldh_1_N 37-179 aa PF02866 Ldh_1_C 181-343 aa PF01127 Sdh_cyt 365-450 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795938.1`	Pfam	`PF00056`	Ldh_1_N	Domain	37	179	6.3e-47	159.9	lactate/malate dehydrogenase, NAD binding domain
`XP_057795938.1`	Pfam	`PF02866`	Ldh_1_C	Domain	181	343	3.1e-48	164.8	lactate/malate dehydrogenase, alpha/beta C-terminal domain
`XP_057795938.1`	Pfam	`PF01127`	Sdh_cyt	Family	365	450	3.7e-11	43.9	Succinate dehydrogenase/Fumarate reductase transmembrane subunit

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057939955.1
CTGGGCCTGCCACTCACAAACCACCAATATATACAACTATTTCATATTTCCATTCACAAACACACGCACTCGTACACACACACTGGAATTTTTCAATCTACCTTTATTTCGGTAATCGAGATTGGGAGGAAAATGACCGCGGCAATGTTGAGATCACTTCTCCGGCGGAGCACGAGCTCCGCTGCGTCGTCGTATTGCTTCTCGAGCCGTCGCTTCTCATCGGGGGCGGCGCCGGAGCGGAAAGTAGCCATTTTGGGCGC...

CDS

1 records

下载 CDS FASTA

LOC131012052
ATGACCGCGGCAATGTTGAGATCACTTCTCCGGCGGAGCACGAGCTCCGCTGCGTCGTCGTATTGCTTCTCGAGCCGTCGCTTCTCATCGGGGGCGGCGCCGGAGCGGAAAGTAGCCATTTTGGGCGCGGCGGGGGGCATCGGACAGCCCCTCTCGCTCCTCATGAAGCTGAATCCTCTCGTCTCCAGGCTCGCTCTCTACGATATCGCCGGCACCCCCGGCGTCGCCGCTGACGTCAGCCACGTCAACACCAGATCTGA...

Protein

1 records

下载 Protein FASTA

XP_057795938.1
MTAAMLRSLLRRSTSSAASSYCFSSRRFSSGAAPERKVAILGAAGGIGQPLSLLMKLNPLVSRLALYDIAGTPGVAADVSHVNTRSEVKGFAGEDQLGQALEGSDIVIIPAGVPRKPGMTRDDLFAINAGIVKSLCEAIAKYCPNALVNMISNPVNSTVPIAAEVFKNHGVYDERKLFGVTTLDVVRAKTFYAGKANVNVADVNVPVIGGHAGITILPLFSQATPKANLSDDDIKALTKRTQDGGTEVVEAKAGKGSATL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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