Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004229`

染色体: Chr02 坐标: 64491924-64496930 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004229`
名称	SmilChr02G004229
描述	probable prolyl 4-hydroxylase 3
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	64491924 - 64496930 / `-`

ID 对照

NCBI Gene ID	`LOC131012973`
GeneID	`131012973`
locus_tag	`-`
NCBI Name	`LOC131012973`
原始查询	`LOC131012973`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable prolyl 4-hydroxylase 3
产物	probable prolyl 4-hydroxylase 3
Arabidopsis	`AT1G20270` (AT1G20270) 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:838615] identity=72.5; qcov=1.01; evalue=7.86e-158; confidence=high
Rice	`Os10g0497800` - identity=78.5; qcov=0.768; evalue=8.78e-127; confidence=high
GO	GO:0004656 (procollagen-proline 4-dioxygenase activity); GO:0005506 (iron ion binding); GO:0005783 (endoplasmic reticulum); GO:0018401 (peptidyl-proline hydroxylation to 4-hydroxy-L-proline); GO:0031418 (L-ascorbic acid binding)
KEGG	smil00330 (Arginine and proline metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF03171 (2OG-FeII_Oxy); PF13640 (2OG-FeII_Oxy_3)
InterPro	-
eggNOG	-
NR	GeneID:131012973

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	1.00000	`XP_057796945.1`
2	Nucleus	细胞核	0.00000	`XP_057796945.1`
3	Chromosome	染色体	0.00000	`XP_057796945.1`
4	Centromere	着丝粒	0.00000	`XP_057796945.1`
5	Chromatin	染色质	0.00000	`XP_057796945.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:64492102`	`C`	`CTT`	2bp_insertion	frameshift_variant	2	B26,C39
`Chr2:64492102`	`C`	`CTT`	2bp_insertion	CDS_variant	2	B26,C39
`Chr2:64492330`	`T`	`TCC`	2bp_insertion	frameshift_variant	4	A8,B24,C11,C14
`Chr2:64492330`	`T`	`TCC`	2bp_insertion	CDS_variant	4	A8,B24,C11,C14
`Chr2:64492355`	`T`	`TAG`	2bp_insertion	frameshift_variant	5	B24,B85,C46,C62,D5
`Chr2:64492355`	`T`	`TAG`	2bp_insertion	CDS_variant	5	B24,B85,C46,C62,D5
`Chr2:64492407`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B108,B50,C23,D7
`Chr2:64492592`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C16
`Chr2:64492606`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A7,A8,B21,B40,C53
`Chr2:64496408`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B61,C43,C55,C65

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057796945.1

285 aa

142

285

2OG-FeII_Oxy

2OG-FeII_Oxy_3

PF03171 2OG-FeII_Oxy 159-279 aa PF13640 2OG-FeII_Oxy_3 161-279 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057796945.1`	Pfam	`PF03171`	2OG-FeII_Oxy	Domain	159	279	9.1e-09	36.3	2OG-Fe(II) oxygenase superfamily
`XP_057796945.1`	Pfam	`PF13640`	2OG-FeII_Oxy_3	Domain	161	279	4.4e-20	73.2	2OG-Fe(II) oxygenase superfamily

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057940962.1
GCTGCCCACTGGACAATAATGAGATTTTTCGCCCCCATTTATGTGCGTAAGCGAAAAATAGAAGAATGGATCACTTAAATTGACAATAGCATTAACTTCATCTTCTTCCCCATTCACATCGCATGCACAAATTCACCACCCTCAGACTTTAAATTTCCGCCTTCTCAAAAATCACCTAATTAATCCCAAACCTATCCCCCTCTGTATTTGTCCTGATTCTTTGATTAGGAATGGCGAAATGGAGGGGCAATCGGCATCTA...

CDS

1 records

下载 CDS FASTA

LOC131012973
ATGGCGAAATGGAGGGGCAATCGGCATCTAGGAAAGATATATTCTAGATCAATTTTGGTGCTATCGATGCTCTTAATGCTGACGGTGTTGCTATTGATAGTTCTCGGACTCGGAATACGCTCTGTTCCTGTTGGCTCAGAAGATGACTCATTGCTCATCAAAGACGGTGTTAGACTAAGCATTGAAGGAGAGGGATTGGGAGGAAGAGGAGATCAGTGGACCGAGGTCGTTTCGTGGGAGCCTAGAGCTTTCATCTACCA...

Protein

1 records

下载 Protein FASTA

XP_057796945.1
MAKWRGNRHLGKIYSRSILVLSMLLMLTVLLLIVLGLGIRSVPVGSEDDSLLIKDGVRLSIEGEGLGGRGDQWTEVVSWEPRAFIYHNFLSKEECEYLINLATPHMVKSTVVDSKTGKSKDSRVRTSYGMFLRRGRDKVIRAIEKRIADYTLIPVEHGEGLQVLHYEVGQKYDPHYDYFVDEINTRNGGQRIATLLMYLSDVEEGGETVFPAAKGNVSSVAGWSGMSECAKKGVSVKPKMGDALLFWSMRPDATLDPSSL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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