Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004324`

染色体: Chr02 坐标: 65539701-65542093 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004324`
名称	SmilChr02G004324
描述	D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	65539701 - 65542093 / `-`

ID 对照

NCBI Gene ID	`LOC131013068`
GeneID	`131013068`
locus_tag	`-`
NCBI Name	`LOC131013068`
原始查询	`LOC131013068`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like
产物	D-3-phosphoglycerate dehydrogenase 2%2C chloroplastic-like
Arabidopsis	`AT1G17745` (PGDH) D-3-phosphoglycerate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:838352] identity=70.7; qcov=0.99; evalue=0; confidence=high
Rice	`Os06g0655100` - identity=70.4; qcov=0.914; evalue=0; confidence=high
GO	GO:0004617 (phosphoglycerate dehydrogenase activity); GO:0006564 (L-serine biosynthetic process); GO:0051287 (NAD binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00389 (2-Hacid_dh); PF01842 (ACT); PF02826 (2-Hacid_dh_C); PF19304 (PGDH_inter)
InterPro	-
eggNOG	-
NR	GeneID:131013068

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057797052.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057797052.1`
3	Nucleus	细胞核	0.00000	`XP_057797052.1`
4	Chromosome	染色体	0.00000	`XP_057797052.1`
5	Centromere	着丝粒	0.00000	`XP_057797052.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:65540128`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B26,B89
`Chr2:65540192`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C64
`Chr2:65540201`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B107,C47,D6
`Chr2:65540550`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B108,B50,C23
`Chr2:65540580`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B95,C14
`Chr2:65540794`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B32
`Chr2:65540872`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr2:65541428`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:65541601`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr2:65541821`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B64,C15
`Chr2:65541852`	`TA`	`T`	1bp_deletion	frameshift_variant	11	A18,B24,B55,B57,B93,C2,C67,C75,C8,C85,D1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797052.1

592 aa

296

592

2-Hacid_dh

2-Hacid_dh_C

PGDH_inter

ACT

PF00389 2-Hacid_dh 53-362 aa PF02826 2-Hacid_dh_C 155-330 aa PF19304 PGDH_inter 374-466 aa PF01842 ACT 520-582 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797052.1`	Pfam	`PF00389`	2-Hacid_dh	Domain	53	362	7.3e-33	113.8	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
`XP_057797052.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	155	330	8.4e-62	208.4	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057797052.1`	Pfam	`PF19304`	PGDH_inter	Domain	374	466	3.4e-14	53.7	D-3-phosphoglycerate dehydrogenase intervening domain
`XP_057797052.1`	Pfam	`PF01842`	ACT	Domain	520	582	3.1e-12	46.7	ACT domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941069.1
TGTCCCCCCAAAATAAAAATAAAAAATAAGAAAAATGGCTTTGTTGATTTTCCGTTATTATAGTTACTGTTACAAGTAAATGAACTGAGTCAACAGAAGCCAAAATACTAGTTTCTGGGTATTAAAATTAAATGATCTTCGTCATATGATGGATTGATCTACTTCTTCTTCAGTTACACAAAAATGGGCGCAATCTCCATTTGGTGTGCCAGTTGTAATCTGAGCAACAAGAAGCAATCTTATCCCATTATTCCGAAAGT...

CDS

1 records

下载 CDS FASTA

LOC131013068
ATGGGCGCAATCTCCATTTGGTGTGCCAGTTGTAATCTGAGCAACAAGAAGCAATCTTATCCCATTATTCCGAAAGTGAGCGTCTCCAGCAATAACAAGAGACGCACCGCTTTGAAGTCAGGAAATTCAGAATCCCAGAAGCCCTCCTCCTGCTCCATCTTAGTCTCCGAGAAGCTCGGAGAAGCGGGACTCGATTTGCTCCGTAAATTTGGTCACGTGGAATGCCTCTACAACCAATCCTTGGAGGAATTGTGTGGCAG...

Protein

1 records

下载 Protein FASTA

XP_057797052.1
MGAISIWCASCNLSNKKQSYPIIPKVSVSSNNKRRTALKSGNSESQKPSSCSILVSEKLGEAGLDLLRKFGHVECLYNQSLEELCGRIGEFDALVVRSGTKVTRRLFEAAKGRLKVVGRAGVGIDNVDRQAATEFGCLVVNAPTANTIAAAEHGIALLTAMARNVAQADASMKAGKWERSKHFGVCVEGKTLAVIGFGRVGSEVARRAKGLGMHVIAHDPYAPADTARGIGVDLVSFDEALSSAHFVSLHMPLTPSTHRL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器