Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G002505`

染色体: Chr02 坐标: 43539195-43543984 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G002505`
名称	SmilChr02G002505
描述	DNA replication licensing factor MCM3 homolog 2-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	43539195 - 43543984 / `+`

ID 对照

NCBI Gene ID	`LOC131013595`
GeneID	`131013595`
locus_tag	`-`
NCBI Name	`LOC131013595`
原始查询	`LOC131013595`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA replication licensing factor MCM3 homolog 2-like
产物	DNA replication licensing factor MCM3 homolog 2-like
Arabidopsis	`AT5G46280` (MCM3) Minichromosome maintenance (MCM2/3/5) family protein [Source:NCBI gene (formerly Entrezgene);Acc:834670] identity=67.9; qcov=0.992; evalue=0; confidence=high
Rice	`Os05g0476200` (OsMCM3) - identity=68; qcov=0.995; evalue=0; confidence=high
GO	GO:0000727 (double-strand break repair via break-induced replication); GO:0003697 (single-stranded DNA binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0006260 (DNA replication); GO:0006271 (DNA strand elongation involved in DNA replication); GO:0016887 (ATP hydrolysis activity); GO:0017116 (single-stranded DNA helicase activity); GO:0032508 (GO:0032508); GO:0042555 (MCM complex); GO:1902975 (mitotic DNA replication initiation)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage))
Pfam	PF00493 (MCM); PF01078 (Mg_chelatase); PF14551 (MCM_N); PF17207 (MCM_OB); PF17855 (MCM_lid); PF23191 (WHD_MCM3_C)
InterPro	-
eggNOG	-
NR	GeneID:131013595

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057797703.1`
2	Chromosome	染色体	0.80000	`XP_057797703.1`
3	Centromere	着丝粒	0.00000	`XP_057797703.1`
4	Chromatin	染色质	0.00000	`XP_057797703.1`
5	Telomere	端粒	0.00000	`XP_057797703.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:43539471`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B112
`Chr2:43539478`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B123,B130,B139,C23
`Chr2:43539692`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C8,D9
`Chr2:43541548`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B123,B133,B33,C39
`Chr2:43542037`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A15,B11,B45
`Chr2:43543148`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr2:43543447`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797703.1

785 aa

392

785

MCM_N

MCM_OB

MCM

Mg_chelatase

MCM_lid

WHD_MCM3_C

PF14551 MCM_N 13-99 aa PF17207 MCM_OB 112-242 aa PF00493 MCM 279-502 aa PF01078 Mg_chelatase 386-453 aa PF17855 MCM_lid 557-641 aa PF23191 WHD_MCM3_C 713-783 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797703.1`	Pfam	`PF14551`	MCM_N	Domain	13	99	4.6e-09	37.3	MCM N-terminal domain
`XP_057797703.1`	Pfam	`PF17207`	MCM_OB	Domain	112	242	3.1e-29	102.0	MCM OB domain
`XP_057797703.1`	Pfam	`PF00493`	MCM	Domain	279	502	3.8e-96	321.2	MCM P-loop domain
`XP_057797703.1`	Pfam	`PF01078`	Mg_chelatase	Domain	386	453	3.8e-09	37.0	Magnesium chelatase, subunit ChlI
`XP_057797703.1`	Pfam	`PF17855`	MCM_lid	Domain	557	641	1.5e-25	90.2	MCM AAA-lid domain
`XP_057797703.1`	Pfam	`PF23191`	WHD_MCM3_C	Domain	713	783	1.6e-10	41.7	MCM3-like, winged helix domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941720.1
AGATAATTTCTTCTCGATTTTTTCCTTACTCCTCTCCCTCGCGCGATCTAATTGGAGGCATTTCCGACTGAAAGGGGAGCTGAAGAAGATTCGGGATGGATCTCAGCGATGATATCAGGACGGCGCACAAGCGCACTTTCCTCAAATTTTTCGAGCAAACTGATTACAACATTGAACTGAAGAAATCTCTCGACCTAATGTTCAACCAAAACCGTCGCCGTTGTGTGATTAATCTCGCTCATTTCTACCACCACAGAGAA...

CDS

1 records

下载 CDS FASTA

LOC131013595
ATGGATCTCAGCGATGATATCAGGACGGCGCACAAGCGCACTTTCCTCAAATTTTTCGAGCAAACTGATTACAACATTGAACTGAAGAAATCTCTCGACCTAATGTTCAACCAAAACCGTCGCCGTTGTGTGATTAATCTCGCTCATTTCTACCACCACAGAGAAGGCACGGATCTGGCGCGAAGGCTCTTGCAAACTCCAAGCGAGTACATACAGCCACTCTGTGATGCGGTGACGGATATGGCTAGGAGCATGAATGC...

Protein

1 records

下载 Protein FASTA

XP_057797703.1
MDLSDDIRTAHKRTFLKFFEQTDYNIELKKSLDLMFNQNRRRCVINLAHFYHHREGTDLARRLLQTPSEYIQPLCDAVTDMARSMNAKYLKEGEQVLVGLEGPFVSRRVTPRDLLSGFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPATDKFTVREYRDITSNIGLPTGSVYPTRDDNGNLLVTEFGLCTYKDHQTLSMQEVPENSAPGQLPRTVDIIVEDDLVDSCKPGDRVAIVGIYKALPGKSKGSVNGVFRTVLIA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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