Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G004272`

染色体: Chr03 坐标: 61178347-61186646 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G004272`
名称	SmilChr03G004272
描述	3beta-hydroxysteroid-dehydrogenase/decarboxylase
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	61178347 - 61186646 / `+`

ID 对照

NCBI Gene ID	`LOC131015149`
GeneID	`131015149`
locus_tag	`-`
NCBI Name	`LOC131015149`
原始查询	`LOC131015149`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	3beta-hydroxysteroid-dehydrogenase/decarboxylase
产物	3beta-hydroxysteroid-dehydrogenase/decarboxylase
Arabidopsis	`AT2G26260` (3BETAHSD/D2) 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 [Source:NCBI gene (formerly Entrezgene);Acc:817166] identity=67.7; qcov=0.989; evalue=0; confidence=high
Rice	`Os03g0405000` - identity=60.8; qcov=0.955; evalue=0; confidence=high
GO	GO:0003854 (3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity); GO:0006694 (steroid biosynthetic process)
KEGG	smil00100 (Steroid biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF02453 (Reticulon); PF02719 (Polysacc_synt_2); PF04321 (RmlD_sub_bind); PF07993 (NAD_binding_4); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131015149

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057799392.1`
2	Endoplasmic reticulum membrane	内质网膜	0.80000	`XP_057799392.1`
3	Nucleus	细胞核	0.00000	`XP_057799392.1`
4	Chromosome	染色体	0.00000	`XP_057799392.1`
5	Centromere	着丝粒	0.00000	`XP_057799392.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:61178749`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C28
`Chr3:61178811`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B20,C44,C49,C57
`Chr3:61178920`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,B19
`Chr3:61180730`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B104,B19
`Chr3:61180969`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B78,C27,C48
`Chr3:61181034`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A11
`Chr3:61181473`	`TG`	`T`	1bp_deletion	frameshift_variant	1	B87
`Chr3:61181473`	`TG`	`T`	1bp_deletion	CDS_variant	1	B87
`Chr3:61181514`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C87
`Chr3:61183180`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B78,C27,C48
`Chr3:61184720`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B104,B19,B78,C27
`Chr3:61184747`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B105,B110,B125,C38,C6

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057799392.1

560 aa

280

560

Polysacc_synt_2

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

Reticulon

PF02719 Polysacc_synt_2 9-129 aa PF01370 Epimerase 9-237 aa PF01073 3Beta_HSD 9-283 aa PF16363 GDP_Man_Dehyd 10-232 aa PF07993 NAD_binding_4 11-229 aa PF04321 RmlD_sub_bind 68-278 aa PF02453 Reticulon 380-537 aa

XP_057799393.1

560 aa

280

560

Polysacc_synt_2

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

Reticulon

XP_057799394.1

560 aa

280

560

Polysacc_synt_2

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

Reticulon

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057799392.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	3.5e-05	23.8	Polysaccharide biosynthesis protein
`XP_057799392.1`	Pfam	`PF01370`	Epimerase	Family	9	237	6.2e-32	111.6	NAD dependent epimerase/dehydratase family
`XP_057799392.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	283	5.4e-75	252.7	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057799392.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	232	7.6e-16	59.2	GDP-mannose 4,6 dehydratase
`XP_057799392.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.7e-11	43.4	Male sterility protein
`XP_057799392.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	68	278	8e-09	35.7	RmlD substrate binding domain
`XP_057799392.1`	Pfam	`PF02453`	Reticulon	Family	380	537	7e-31	108.0	Reticulon
`XP_057799393.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	3.5e-05	23.8	Polysaccharide biosynthesis protein
`XP_057799393.1`	Pfam	`PF01370`	Epimerase	Family	9	237	6.2e-32	111.6	NAD dependent epimerase/dehydratase family
`XP_057799393.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	283	5.4e-75	252.7	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057799393.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	232	7.6e-16	59.2	GDP-mannose 4,6 dehydratase
`XP_057799393.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.7e-11	43.4	Male sterility protein
`XP_057799393.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	68	278	8e-09	35.7	RmlD substrate binding domain
`XP_057799393.1`	Pfam	`PF02453`	Reticulon	Family	380	537	7e-31	108.0	Reticulon
`XP_057799394.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	3.5e-05	23.8	Polysaccharide biosynthesis protein
`XP_057799394.1`	Pfam	`PF01370`	Epimerase	Family	9	237	6.2e-32	111.6	NAD dependent epimerase/dehydratase family
`XP_057799394.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	283	5.4e-75	252.7	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057799394.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	232	7.6e-16	59.2	GDP-mannose 4,6 dehydratase
`XP_057799394.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.7e-11	43.4	Male sterility protein
`XP_057799394.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	68	278	8e-09	35.7	RmlD substrate binding domain
`XP_057799394.1`	Pfam	`PF02453`	Reticulon	Family	380	537	7e-31	108.0	Reticulon

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057943410.1
ATTTACAATGTGTCGGAGGCGGTAATTTTTTTTGTGGAACTAAATAAAATTGTTAATTAACTACATAATTAATCTTTTTTTATTGAATAATCTATTTTTGATGATTCACTCTGCTAATCCGAACGGTTCTCACTGTCAGTCCAAGATCCAGTTGGCAGCTTGCGTTTTCCTAACTCATACAAGCTGTTTCCGGCTGATACGACGTCGCTTTAACATCGCCTGAAGTACTCAACGCCGGGGAAATGGGCGGCGAAGAGAAG...

XM_057943411.1
ATTTACAATGTGTCGGAGGCGGTAATTTTTTTTGTGGAACTAAATAAAATTGTTAATTAACTACATAATTAATCTTTTTTTATTGAATAATCTATTTTTGATGATTCACTCTGCTAATCCGAACGGTTCTCACTGTCAGTCCAAGATCCAGTTGGCAGCTTGCGTTTTCCTAACTCATACAAGCTGTTTCCGGCTGATACGACGTCGCTTTAACATCGCCTGAAGTACTCAACGCCGGGGAAATGGGCGGCGAAGAGAAG...

CDS

3 records

下载 CDS FASTA

LOC131015149
ATGGGCGGCGAAGAGAAGTGGTGCGTGGTGACCGGCGGCAGGGGATTTGCGGCTCGGCATCTGGTGGTGATGCTCATCAAATACGGCATGTTTTCGGTTCGCATTGCGGATTTGGGCCCCGCCATCAAGCTCGACAAGGACGAGGAGAACGGGGTTCTCGGCGAAGCTCTGAAATCCGGCCGTGCCGAATACGTGTCTGCAGATCTTCGCAACAAAGCGCAAGTGCTTAAGGCTTGCATAGGAGTTGTGGTTGTATTCCA...

Protein

3 records

下载 Protein FASTA

XP_057799392.1
MGGEEKWCVVTGGRGFAARHLVVMLIKYGMFSVRIADLGPAIKLDKDEENGVLGEALKSGRAEYVSADLRNKAQVLKACIGVVVVFHMAAPDSSINNHRLHYSVNVQGTQNIVDVCFKLKIKRLIYTSSPSVVFDGVNGISNGNESLPYPAKHYDSYSATKAEGESLVINSNGSNGLLTCCLRPSSIFGPGDRLFVPSLASAARSGKLKFIIGNGNNMYDFTYVENVAHAHICAERALASEGAVADKAAGQAYFITNGEP...

XP_057799393.1
MGGEEKWCVVTGGRGFAARHLVVMLIKYGMFSVRIADLGPAIKLDKDEENGVLGEALKSGRAEYVSADLRNKAQVLKACIGVVVVFHMAAPDSSINNHRLHYSVNVQGTQNIVDVCFKLKIKRLIYTSSPSVVFDGVNGISNGNESLPYPAKHYDSYSATKAEGESLVINSNGSNGLLTCCLRPSSIFGPGDRLFVPSLASAARSGKLKFIIGNGNNMYDFTYVENVAHAHICAERALASEGAVADKAAGQAYFITNGEP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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