Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G003170`

染色体: Chr03 坐标: 49051056-49060166 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G003170`
名称	SmilChr03G003170
描述	methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	49051056 - 49060166 / `-`

ID 对照

NCBI Gene ID	`LOC131016311`
GeneID	`131016311`
locus_tag	`-`
NCBI Name	`LOC131016311`
原始查询	`LOC131016311`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
产物	methylcrotonoyl-CoA carboxylase subunit alpha%2C mitochondrial
Arabidopsis	`AT1G03090` (MCCA) methylcrotonyl-CoA carboxylase alpha chain [Source:NCBI gene (formerly Entrezgene);Acc:838362] identity=70.5; qcov=0.99; evalue=0; confidence=high
Rice	`Os12g0605800` (OsL55) - identity=67.8; qcov=0.998; evalue=0; confidence=high
GO	GO:0004485 (methylcrotonoyl-CoA carboxylase activity); GO:0005524 (ATP binding); GO:0005739 (mitochondrion); GO:0046872 (metal ion binding)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF00289 (Biotin_carb_N); PF00364 (Biotin_lipoyl); PF02785 (Biotin_carb_C); PF02786 (CPSase_L_D2); PF07478 (Dala_Dala_lig_C); PF19331 (MCCA_BT)
InterPro	-
eggNOG	-
NR	GeneID:131016311

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057800969.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057800969.1`
3	Cytoplasm	细胞质	0.80000	`XP_057800972.1`
4	Cytosol	细胞质基质	0.80000	`XP_057800972.1`
5	Nucleus	细胞核	0.20000	`XP_057800972.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:49052188`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C38,C39
`Chr3:49052190`	`T`	`TA`	1bp_insertion	frameshift_variant	1	B19
`Chr3:49052190`	`T`	`TA`	1bp_insertion	CDS_variant	1	B19
`Chr3:49052219`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B75,C54
`Chr3:49052250`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C38,C39
`Chr3:49052270`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr3:49052506`	`GGT`	`G`	2bp_deletion	frameshift_variant	1	B111
`Chr3:49052506`	`GGT`	`G`	2bp_deletion	CDS_variant	1	B111
`Chr3:49052518`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B1
`Chr3:49053349`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B28,B35
`Chr3:49055243`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B91
`Chr3:49056345`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C38,C39

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057800969.1

739 aa

370

739

Biotin_carb_N

CPSase_L_D2

Dala_Dala_lig_C

Biotin_carb_C

MCCA_BT

Biotin_lipoyl

PF00289 Biotin_carb_N 37-145 aa PF02786 CPSase_L_D2 150-358 aa PF07478 Dala_Dala_lig_C 177-327 aa PF02785 Biotin_carb_C 372-479 aa PF19331 MCCA_BT 493-647 aa PF00364 Biotin_lipoyl 662-726 aa

XP_057800970.1

730 aa

365

730

Biotin_carb_N

CPSase_L_D2

Dala_Dala_lig_C

Biotin_carb_C

MCCA_BT

Biotin_lipoyl

XP_057800971.1

670 aa

335

670

Biotin_carb_N

CPSase_L_D2

Dala_Dala_lig_C

Biotin_carb_C

MCCA_BT

PF00289 Biotin_carb_N 37-145 aa PF02786 CPSase_L_D2 150-358 aa PF07478 Dala_Dala_lig_C 177-327 aa PF02785 Biotin_carb_C 372-479 aa PF19331 MCCA_BT 493-615 aa

XP_057800972.1

592 aa

296

592

CPSase_L_D2

Dala_Dala_lig_C

Biotin_carb_C

MCCA_BT

Biotin_lipoyl

PF02786 CPSase_L_D2 3-211 aa PF07478 Dala_Dala_lig_C 30-180 aa PF02785 Biotin_carb_C 225-332 aa PF19331 MCCA_BT 346-500 aa PF00364 Biotin_lipoyl 515-579 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057800969.1`	Pfam	`PF00289`	Biotin_carb_N	Domain	37	145	1.7e-45	154.7	Biotin carboxylase, N-terminal domain
`XP_057800969.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	150	358	3.1e-74	249.8	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057800969.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	177	327	6.8e-09	36.2	D-ala D-ala ligase C-terminus
`XP_057800969.1`	Pfam	`PF02785`	Biotin_carb_C	Domain	372	479	2.2e-34	118.5	Biotin carboxylase C-terminal domain
`XP_057800969.1`	Pfam	`PF19331`	MCCA_BT	Domain	493	647	2.4e-66	223.0	Methylcrotonoyl-CoA carboxylase subunit alpha BT domain
`XP_057800969.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	662	726	2.2e-18	66.5	Biotin-requiring enzyme
`XP_057800970.1`	Pfam	`PF00289`	Biotin_carb_N	Domain	37	145	1.7e-45	154.7	Biotin carboxylase, N-terminal domain
`XP_057800970.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	150	358	3e-74	249.8	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057800970.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	177	327	6.7e-09	36.3	D-ala D-ala ligase C-terminus
`XP_057800970.1`	Pfam	`PF02785`	Biotin_carb_C	Domain	372	479	2.2e-34	118.5	Biotin carboxylase C-terminal domain
`XP_057800970.1`	Pfam	`PF19331`	MCCA_BT	Domain	493	647	2.4e-66	223.1	Methylcrotonoyl-CoA carboxylase subunit alpha BT domain
`XP_057800970.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	662	726	2.2e-18	66.6	Biotin-requiring enzyme
`XP_057800971.1`	Pfam	`PF00289`	Biotin_carb_N	Domain	37	145	1.8e-45	154.6	Biotin carboxylase, N-terminal domain
`XP_057800971.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	150	358	2.5e-74	250.1	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057800971.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	177	327	5.5e-09	36.5	D-ala D-ala ligase C-terminus
`XP_057800971.1`	Pfam	`PF02785`	Biotin_carb_C	Domain	372	479	2.1e-34	118.6	Biotin carboxylase C-terminal domain
`XP_057800971.1`	Pfam	`PF19331`	MCCA_BT	Domain	493	615	2.1e-47	161.4	Methylcrotonoyl-CoA carboxylase subunit alpha BT domain
`XP_057800972.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	3	211	2.1e-74	250.3	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057800972.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	30	180	4.8e-09	36.7	D-ala D-ala ligase C-terminus
`XP_057800972.1`	Pfam	`PF02785`	Biotin_carb_C	Domain	225	332	1.5e-34	119.0	Biotin carboxylase C-terminal domain
`XP_057800972.1`	Pfam	`PF19331`	MCCA_BT	Domain	346	500	1.7e-66	223.6	Methylcrotonoyl-CoA carboxylase subunit alpha BT domain
`XP_057800972.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	515	579	1.6e-18	67.0	Biotin-requiring enzyme

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057944987.1
GCAATAATACAGACAAAATAATTTAAATTAAAACTAACAGACAACATCTCATAACTTCTAAGCTCCCTTCGTTTCCTTCTAAACTGTAAATTCATTAGATACACTACAATTGTGAAACGATGTCGTCTTTAGCTTCTCTAATCCGCAGAAGAAGCAAGCCAATAACTCTTCGGCTGAGAGGATTCTCGTCGAGTGCGCCCAATTCGATCGACCGAACTAGTGGAAGAATTGACAAGTTATTAATCGCGAATAGAGGCGAA...

XM_057944986.1
AATTTAAATTAAAACTAACAGACAACATCTCATAACTTCTAAGCTCCCTTCGTTTCCTTCTAAACTGTAAATTCATTAGATACACTACAATTGTGAAACGATGTCGTCTTTAGCTTCTCTAATCCGCAGAAGAAGCAAGCCAATAACTCTTCGGCTGAGAGGATTCTCGTCGAGTGCGCCCAATTCGATCGACCGAACTAGTGGAAGAATTGACAAGTTATTAATCGCGAATAGAGGCGAAATCGCCTGCAGGATAATGC...

CDS

4 records

下载 CDS FASTA

LOC131016311
ATGTCGTCTTTAGCTTCTCTAATCCGCAGAAGAAGCAAGCCAATAACTCTTCGGCTGAGAGGATTCTCGTCGAGTGCGCCCAATTCGATCGACCGAACTAGTGGAAGAATTGACAAGTTATTAATCGCGAATAGAGGCGAAATCGCCTGCAGGATAATGCGTACCGCCAAGCGATTGGGGATTCGAACTGTCGCTGTTTACAGCGACGCCGACGAGCGGAGCTTGCACGTCAAATTGGCTGACGAAGCCGTTCGCATTGG...

Protein

4 records

下载 Protein FASTA

XP_057800969.1
MSSLASLIRRRSKPITLRLRGFSSSAPNSIDRTSGRIDKLLIANRGEIACRIMRTAKRLGIRTVAVYSDADERSLHVKLADEAVRIGPPPARLSYLSAASIIQAASRTGAQAIHPGYGFLSESAEFAQLCEDEGLTFVGPPASAIRDMGDKSASKRIMGAAGVPLVPGYHGYEQDIDLMKLEADKIGYPILIKPTHGGGGKGMRIVHSPEDFVDSFIGAQREAAASFGINTILLEKYITKPRHIEVQIFGDKHGNIVHLN...

XP_057800970.1
MSSLASLIRRRSKPITLRLRGFSSSAPNSIDRTSGRIDKLLIANRGEIACRIMRTAKRLGIRTVAVYSDADERSLHVKLADEAVRIGPPPARLSYLSAASIIQAASRTGAQAIHPGYGFLSESAEFAQLCEDEGLTFVGPPASAIRDMGDKSASKRIMGAAGVPLVPGYHGYEQDIDLMKLEADKIGYPILIKPTHGGGGKGMRIVHSPEDFVDSFIGAQREAAASFGINTILLEKYITKPRHIEVQIFGDKHGNIVHLN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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