Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G002524`

染色体: Chr03 坐标: 40226530-40229739 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G002524`
名称	SmilChr03G002524
描述	heat shock cognate 70 kDa protein 2
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	40226530 - 40229739 / `-`

ID 对照

NCBI Gene ID	`LOC131016687`
GeneID	`131016687`
locus_tag	`-`
NCBI Name	`LOC131016687`
原始查询	`LOC131016687`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	heat shock cognate 70 kDa protein 2
产物	heat shock cognate 70 kDa protein 2
Arabidopsis	`AT5G02500` (HSC70-1) heat shock cognate protein 70-1 [Source:NCBI gene (formerly Entrezgene);Acc:831020] identity=92.5; qcov=1.01; evalue=0; confidence=high
Rice	`Os11g0703900` (HSP70) - identity=94.6; qcov=1; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0016887 (ATP hydrolysis activity); GO:0031072 (heat shock protein binding); GO:0034620 (cellular response to unfolded protein); GO:0042026 (protein refolding); GO:0051082 (GO:0051082); GO:0051085 (GO:0051085); GO:0051787 (misfolded protein binding); GO:0140662 (ATP-dependent protein folding chaperone)
KEGG	smil03040 (Spliceosome - Salvia miltiorrhiza (redroot sage)); smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage)); smil04144 (Endocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00012 (HSP70); PF06723 (MreB_Mbl)
InterPro	-
eggNOG	-
NR	GeneID:131016687

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057801374.1`
2	Cytosol	细胞质基质	1.00000	`XP_057801374.1`
3	Nucleus	细胞核	0.80000	`XP_057801374.1`
4	Nucleoplasm	核质	0.60000	`XP_057801374.1`
5	Midbody	Midbody	0.20000	`XP_057801374.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:40226745`	`GGT`	`G`	2bp_deletion	frameshift_variant	3	B82,B92,C56
`Chr3:40226745`	`GGT`	`G`	2bp_deletion	CDS_variant	3	B82,B92,C56
`Chr3:40226753`	`CA`	`C`	1bp_deletion	frameshift_variant	2	B118,B126
`Chr3:40226753`	`CA`	`C`	1bp_deletion	CDS_variant	2	B118,B126
`Chr3:40226772`	`ACC`	`A`	2bp_deletion	frameshift_variant	6	B118,B126,B82,B92,C49,C56
`Chr3:40226846`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B119,B34,C8
`Chr3:40226861`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B119,B34,B38,C8
`Chr3:40226893`	`T`	`TA`	1bp_insertion	frameshift_variant	1	C8
`Chr3:40226893`	`T`	`TA`	1bp_insertion	CDS_variant	1	C8
`Chr3:40226895`	`CT`	`C`	1bp_deletion	frameshift_variant	1	C8
`Chr3:40226895`	`CT`	`C`	1bp_deletion	CDS_variant	1	C8
`Chr3:40227104`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B118,B139,B14,B31

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057801374.1

647 aa

324

647

HSP70

MreB_Mbl

PF00012 HSP70 9-618 aa PF06723 MreB_Mbl 141-380 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057801374.1`	Pfam	`PF00012`	HSP70	Family	9	618	6.1e-262	870.9	Hsp70 protein
`XP_057801374.1`	Pfam	`PF06723`	MreB_Mbl	Family	141	380	8e-14	51.9	MreB/Mbl protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057945391.1
AAAGGAAAAAGAGAATAGGAGAAAAGAGAAAAGAAATACTATGAGGCGCGTGGTCGGCAGATCTGGAATCAGGCGGCCAAGTAGAAAAAGTTCAAAACAAGTTCAAACCTAGCATTCTCTCGGCGCAAATACCGCACCTCATCTCCACCGTTGGCCTTCTAATCCAACGTCTCTTAACAATTAGGGTTTATTCGGAACATTCTGGAACGTCAAACTCAGCTCCCATCCTCAAATATAAATACCAGCTCATTTTCTCTTGC...

CDS

1 records

下载 CDS FASTA

LOC131016687
ATGGCTGGAAAAGGAGAGGGTCCGGCCATCGGAATCGATCTCGGTACCACGTATTCGTGCGTCGGCGTGTGGCAGCACGACCGTGTTGAGATCATCGCCAATGACCAGGGAAACAGAACCACGCCGTCGTATGTTGGCTTCACCGATTCAGAGCGTCTCATTGGTGACGCCGCCAAGAATCAGGTCGCCATGAACCCGATTAACACAGTTTTTGATGCTAAGAGGTTGATTGGAAGGCGTTTTACTGACGCCTCTGTTCA...

Protein

1 records

下载 Protein FASTA

XP_057801374.1
MAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVGFTDSERLIGDAAKNQVAMNPINTVFDAKRLIGRRFTDASVQSDMKLWPFKVIPGPGDKPMIIVNYKGEEKQFAAEEISSMVLMKMREIAEAYLGSAVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDIS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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