Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G001351`

染色体: Chr01 坐标: 26788890-26794211 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G001351`
名称	SmilChr01G001351
描述	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	26788890 - 26794211 / `+`

ID 对照

NCBI Gene ID	`LOC131017444`
GeneID	`131017444`
locus_tag	`-`
NCBI Name	`LOC131017444`
原始查询	`LOC131017444`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic
产物	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase%2C chloroplastic
Arabidopsis	`AT2G26930` (CDPMEK) 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [Source:NCBI gene (formerly Entrezgene);Acc:817234] identity=75.5; qcov=0.843; evalue=0; confidence=high
Rice	`Os01g0802100` (OsIspE) - identity=75.3; qcov=0.891; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0009507 (chloroplast); GO:0016114 (terpenoid biosynthetic process); GO:0050515 (4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity)
KEGG	smil00900 (Terpenoid backbone biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00288 (GHMP_kinases_N); PF08544 (GHMP_kinases_C)
InterPro	-
eggNOG	-
NR	GeneID:131017444

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057802185.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057802185.1`
3	Nucleus	细胞核	0.00000	`XP_057802185.1`
4	Chromosome	染色体	0.00000	`XP_057802185.1`
5	Centromere	着丝粒	0.00000	`XP_057802185.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:26789165`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C25
`Chr1:26789331`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr1:26789336`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A8,B103,C46
`Chr1:26789626`	`C`	`CA`	1bp_insertion	frameshift_variant	1	B119
`Chr1:26789626`	`C`	`CA`	1bp_insertion	CDS_variant	1	B119
`Chr1:26789640`	`C`	`CT`	1bp_insertion	frameshift_variant	1	C78
`Chr1:26789640`	`C`	`CT`	1bp_insertion	CDS_variant	1	C78
`Chr1:26789968`	`A`	`AT`	1bp_insertion	frameshift_variant	215	A11,A13,A14,A15,A16,A18,A19,A2,A20,A21,A23,A24,A3,A5,A6,A7,A8,A9,B1,B10,B100,B101,B102,B103,B104,B105,B107,B108,B109,B11,B111,B112,B114,B115,B117,B119,B120,B121,B122,B124,B125,B126,B127,B128,B129,B13,B130,B131,B132,B133,B134,B135,B136,B137,B138,B139,B14,B15,B16,B18,B19,B2,B20,B21,B22,B23,B24,B25,B26,B27,B29,B3,B30,B31,B32,B33,B34,B35,B36,B37,B38,B39,B4,B40,B41,B42,B43,B44,B45,B47,B48,B49,B5,B51,B52,B53,B54,B55,B56,B57,B59,B6,B61,B62,B65,B67,B68,B69,B70,B71,B72,B73,B75,B76,B79,B80,B83,B84,B86,B87,B88,B9,B90,B91,B92,B94,B95,B96,B97,B98,B99,C1,C10,C11,C12,C13,C14,C15,C16,C17,C18,C19,C20,C21,C23,C24,C25,C26,C27,C28,C29,C3,C30,C31,C32,C33,C34,C36,C37,C38,C39,C4,C40,C41,C42,C43,C44,C45,C46,C47,C48,C49,C5,C50,C52,C55,C56,C57,C58,C59,C62,C63,C64,C65,C66,C67,C68,C69,C7,C70,C71,C72,C73,C74,C76,C77,C78,C8,C80,C81,C83,C84,C85,C86,C87,C9,D10,D11,D2,D3,D4,D6,D7,D8,D9
`Chr1:26789974`	`T`	`TTA`	2bp_insertion	frameshift_variant	22	A18,B121,B125,B15,B26,B40,B44,B59,B67,B69,B98,C14,C25,C29,C41,C42,C48,C59,C63,C77,C86,D3
`Chr1:26790038`	`ACG`	`A`	2bp_deletion	frameshift_variant	43	A10,A13,A24,A7,B103,B105,B111,B113,B123,B137,B19,B21,B25,B28,B33,B36,B39,B5,B52,B6,B64,B83,B85,B93,C12,C2,C25,C36,C59,C6,C62,C69,C7,C77,C79,C8,C81,D1,D10,D4,D5,D8,D9
`Chr1:26790313`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A5,C31,C57
`Chr1:26790403`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B99

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057802185.1

396 aa

198

396

GHMP_kinases_N

GHMP_kinases_C

PF00288 GHMP_kinases_N 156-232 aa PF08544 GHMP_kinases_C 305-358 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057802185.1`	Pfam	`PF00288`	GHMP_kinases_N	Domain	156	232	6.5e-14	52.6	GHMP kinases N terminal domain
`XP_057802185.1`	Pfam	`PF08544`	GHMP_kinases_C	Domain	305	358	0.00011	23.2	GHMP kinases C terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057946202.1
TAAATAAAACGCACACCATAGAAGAATGAAGAATGGTGCAACTGCAATCAGTAAAATCGCTGACCAATGCAAAAGGACTCTCTCTCTCTCTCTGGTCTAAACATAGGCAGCAGCAAGAAAATTTATGTTGGTTTTGAATAAGTTTGAATTGCGGAATCTTTAATCTGCCAAATATTGAATGCTATTTATTCCACATTTACCATAATTTTAGTGTAGCAGTCAGTCATTGGTTTTGGTGGGCTACTTGCTTCTCTCTCCAA...

CDS

1 records

下载 CDS FASTA

LOC131017444
ATGGCTTCCTCTTCCTCCCAATTCCTCTGCACTCACAATCCTAAACCACATTTCAATTCATTCACCAACGCCACTCTTCCTCAATTTTCTTCCTTTAAGCCAAATGGCTCCTCGTCTTTACGCAAAAAGATTCAGTCTTCAAGAATCCATCTTATCAGAGCGACGGCTTCTGATTCCACCACCGGCAGAAAACAACTAGAGGTGGTATATGATCTTGAGAATAAGTTAAATAAGTTAGCTGATGAAGTGGATAGGGATGC...

Protein

1 records

下载 Protein FASTA

XP_057802185.1
MASSSSQFLCTHNPKPHFNSFTNATLPQFSSFKPNGSSSLRKKIQSSRIHLIRATASDSTTGRKQLEVVYDLENKLNKLADEVDRDAGISRLTLFSPCKINVFLRITGKRADGFHDLASLFHVISLGDKIKFSLSPSKSTDRLSTNVPGVPLDERNLIIKALNLFRKKTGIDNYFWIHLDKKVPTGAGLGGGSSNAATALWAANQFSGCVASEKDLQEWSGEIGSDIPFFFSHGAAYCTGRGEVVEDIPPPVPLDLPMVL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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