Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G001589`

染色体: Chr01 坐标: 29915355-29919276 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G001589`
名称	SmilChr01G001589
描述	serine hydroxymethyltransferase 7-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	29915355 - 29919276 / `-`

ID 对照

NCBI Gene ID	`LOC131019027`
GeneID	`131019027`
locus_tag	`-`
NCBI Name	`LOC131019027`
原始查询	`LOC131019027`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	serine hydroxymethyltransferase 7-like
产物	serine hydroxymethyltransferase 7-like
Arabidopsis	`AT1G22020` (SHM6) serine hydroxymethyltransferase 6 [Source:NCBI gene (formerly Entrezgene);Acc:838807] identity=66.5; qcov=0.989; evalue=0; confidence=high
Rice	`Os01g0874900` (OsSHM4) - identity=73.4; qcov=0.777; evalue=0; confidence=high
GO	GO:0004372 (glycine hydroxymethyltransferase activity); GO:0005737 (cytoplasm); GO:0006565 (L-serine catabolic process); GO:0008270 (zinc ion binding); GO:0019264 (GO:0019264); GO:0030170 (pyridoxal phosphate binding); GO:0035999 (tetrahydrofolate interconversion); GO:0046655 (folic acid metabolic process); GO:0050897 (cobalt ion binding); GO:0070905 (serine binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00460 (Cyanoamino acid metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil04981 (Folate transport and metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00266 (Aminotran_5); PF00464 (SHMT)
InterPro	-
eggNOG	-
NR	GeneID:131019027

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057803698.1`
2	Cytosol	细胞质基质	1.00000	`XP_057803698.1`
3	Nucleus	细胞核	0.20000	`XP_057803698.1`
4	Chromosome	染色体	0.00000	`XP_057803698.1`
5	Centromere	着丝粒	0.00000	`XP_057803698.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:29915950`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B113,B53,B58,B70,C20
`Chr1:29916847`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B82
`Chr1:29918214`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B113,B53,B58,B70,C20
`Chr1:29918244`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B113,B53,B58,B70,C20
`Chr1:29918351`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B114
`Chr1:29918403`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C60

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057803698.1

610 aa

305

610

SHMT

Aminotran_5

PF00464 SHMT 154-558 aa PF00266 Aminotran_5 341-479 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057803698.1`	Pfam	`PF00464`	SHMT	Domain	154	558	1.1e-166	555.2	Serine hydroxymethyltransferase
`XP_057803698.1`	Pfam	`PF00266`	Aminotran_5	Domain	341	479	7.6e-05	22.6	Aminotransferase class-V

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009100106.1
CTCTGCCGGCCCTTCACCCCAACTATCCTGGTACTAAAAATCACAGCCAGTGACCGGAATCTCATCCTCTCATAAAACCGTCTACATTCATTCCCCCTCTCCTTCTCGTCTCGTCTCGTCAAACCCACGCTTCTCCTCCTCCTCCTCCTCATATATTACTATTATACTCCCTCTTTCATCATCATTAACCTTTTCACTATTTACATCTCGATTTCTCCAATTATCTCTCCATTTCTCATTATTCTTTCTATGGAACTTTC...

XM_057947715.1
AGCAGGAGTATGGGCCAGAAGAAAGCCCATCGCAGGGAATTCCTGCTCTGCCGGCCCTTCACCCCAACTATCCTGGTACTAAAAATCACAGCCAGTGACCGGAATCTCATCCTCTCATAAAACCGTCTACATTCATTCCCCCTCTCCTTCTCGTCTCGTCTCGTCAAACCCACGCTTCTCCTCCTCCTCCTCCTCATATATTACTATTATACTCCCTCTTTCATCATCATTAACCTTTTCACTATTTACATCTCGATTTC...

CDS

1 records

下载 CDS FASTA

LOC131019027
ATGGATTTGACTCAACCGCCGGCAAACAAAGGTCTTTCGCTAGGGTTTCTGTCCCACGCATCTGATACGCCTCCGTTGGTGAAAAGCAACCGGATCCCTAGCCCTAAAATCGCCGACGATTCGATTTCTTTTCAGATCGAGTCGCGCAGTAGGGACCCTTCGCATCCGCTGCCGCCTGTTCCACTTCAATTGATGGACCAGCAGAAGGAGAATCACCATAATTATTTTCGTGGGGGCAACGATTTGAATGAAACTAGGGA...

Protein

1 records

下载 Protein FASTA

XP_057803698.1
MDLTQPPANKGLSLGFLSHASDTPPLVKSNRIPSPKIADDSISFQIESRSRDPSHPLPPVPLQLMDQQKENHHNYFRGGNDLNETRDVEEEEDEEKLEEFRILGHSMTLKRKRDCDSGWSSASPPSSSKGVRVSSNSDMESRRIAVRSWGNQSLRDADPDIFEIMEKEKGRQFKGIELIASENFVCKAVMEALGSYLTNKYSEGMPGARYYGGNQYIDEIETLCCERALTAFSLDSEGWGVNVQPYSCTSANFAVYTGLL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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