Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G001348`

染色体: Chr04 坐标: 21862646-21872150 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G001348`
名称	SmilChr04G001348
描述	LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.8
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	21862646 - 21872150 / `+`

ID 对照

NCBI Gene ID	`LOC131019393`
GeneID	`131019393`
locus_tag	`-`
NCBI Name	`LOC131019393`
原始查询	`LOC131019393`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.8
产物	LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.8
Arabidopsis	`AT1G67000` (AT1G67000) Protein kinase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:843018] identity=42.4; qcov=0.543; evalue=5.62e-99; confidence=medium
Rice	`Os01g0117300` (OsRLCK17) - identity=51; qcov=0.445; evalue=2.26e-113; confidence=low
GO	GO:0004672 (protein kinase activity); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00069 (Pkinase); PF07714 (PK_Tyr_Ser-Thr); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131019393

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057803919.1`
2	Nucleus	细胞核	0.00000	`XP_057803919.1`
3	Chromosome	染色体	0.00000	`XP_057803919.1`
4	Centromere	着丝粒	0.00000	`XP_057803919.1`
5	Chromatin	染色质	0.00000	`XP_057803919.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:21862792`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr4:21862803`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A1,C18
`Chr4:21862820`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:21862947`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C8
`Chr4:21862994`	`A`	`AT`	1bp_insertion	frameshift_variant	1	B99
`Chr4:21862994`	`A`	`AT`	1bp_insertion	CDS_variant	1	B99
`Chr4:21863003`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:21863062`	`CT`	`C`	1bp_deletion	frameshift_variant	51	A16,A19,A21,A6,B10,B104,B105,B108,B109,B117,B124,B126,B129,B18,B27,B34,B4,B45,B48,B49,B51,B54,B59,B60,B61,B63,B64,B65,B72,B73,B75,B79,B80,B83,B84,B87,B91,B97,C12,C14,C20,C28,C29,C40,C5,C70,C71,C78,C84,D11,D9
`Chr4:21863065`	`T`	`TC`	1bp_insertion	frameshift_variant	40	A13,A2,A25,A8,A9,B102,B106,B111,B12,B13,B134,B16,B28,B35,B4,B46,B47,B55,B60,B65,B68,B71,B77,B8,B85,B98,B99,C20,C23,C32,C48,C5,C61,C68,C72,C73,C80,C86,D5,D8
`Chr4:21863119`	`TC`	`T`	1bp_deletion	frameshift_variant	8	B125,B31,B42,B43,B82,B88,C41,C48
`Chr4:21863120`	`C`	`CA`	1bp_insertion	frameshift_variant	11	A1,B25,B31,B42,B43,B67,B82,B88,C18,C21,C48
`Chr4:21863121`	`TCC`	`T`	2bp_deletion	frameshift_variant	3	B124,B59,B79

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057803919.1

793 aa

396

793

GUB_WAK_bind

PK_Tyr_Ser-Thr

Pkinase

PF13947 GUB_WAK_bind 46-109 aa PF07714 PK_Tyr_Ser-Thr 466-742 aa PF00069 Pkinase 468-740 aa

XP_057803920.1

783 aa

392

783

GUB_WAK_bind

PK_Tyr_Ser-Thr

Pkinase

PF13947 GUB_WAK_bind 46-109 aa PF07714 PK_Tyr_Ser-Thr 456-732 aa PF00069 Pkinase 458-730 aa

XP_057803921.1

761 aa

380

761

GUB_WAK_bind

PK_Tyr_Ser-Thr

Pkinase

PF13947 GUB_WAK_bind 46-109 aa PF07714 PK_Tyr_Ser-Thr 434-710 aa PF00069 Pkinase 436-708 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057803919.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	46	109	4.3e-16	59.8	Wall-associated receptor kinase galacturonan-binding
`XP_057803919.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	466	742	7.6e-45	153.9	Protein tyrosine and serine/threonine kinase
`XP_057803919.1`	Pfam	`PF00069`	Pkinase	Domain	468	740	9.7e-46	157.0	Protein kinase domain
`XP_057803920.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	46	109	4.2e-16	59.8	Wall-associated receptor kinase galacturonan-binding
`XP_057803920.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	456	732	7.4e-45	154.0	Protein tyrosine and serine/threonine kinase
`XP_057803920.1`	Pfam	`PF00069`	Pkinase	Domain	458	730	9.5e-46	157.0	Protein kinase domain
`XP_057803921.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	46	109	4e-16	59.9	Wall-associated receptor kinase galacturonan-binding
`XP_057803921.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	434	710	7e-45	154.1	Protein tyrosine and serine/threonine kinase
`XP_057803921.1`	Pfam	`PF00069`	Pkinase	Domain	436	708	9e-46	157.1	Protein kinase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057947936.1
TAGTGTCTGGTTGAGTCATATATAGCTCCTCCAAAAAGAGTAGAATATGTATGCTGCTTGTGCAAAATCAATTAATTCCATCACATACCATGATCACTCAAAACCCCATCTTCCTCACCATTTCATCTCTCTTGATTCTCTCACTACTCAATAATTTGTTTCAAACTTGTGTTGCAAACTCTTATTGCAGTCCTTCTGCGTGTGGCATCTTTCCCAATATCAGCTCCCCTTTCCGCCTCAAGGGCCATCCAAAGAAGTGC...

XM_057947937.1
TAGTGTCTGGTTGAGTCATATATAGCTCCTCCAAAAAGAGTAGAATATGTATGCTGCTTGTGCAAAATCAATTAATTCCATCACATACCATGATCACTCAAAACCCCATCTTCCTCACCATTTCATCTCTCTTGATTCTCTCACTACTCAATAATTTGTTTCAAACTTGTGTTGCAAACTCTTATTGCAGTCCTTCTGCGTGTGGCATCTTTCCCAATATCAGCTCCCCTTTCCGCCTCAAGGGCCATCCAAAGAAGTGC...

CDS

3 records

下载 CDS FASTA

LOC131019393
ATGCTGCTTGTGCAAAATCAATTAATTCCATCACATACCATGATCACTCAAAACCCCATCTTCCTCACCATTTCATCTCTCTTGATTCTCTCACTACTCAATAATTTGTTTCAAACTTGTGTTGCAAACTCTTATTGCAGTCCTTCTGCGTGTGGCATCTTTCCCAATATCAGCTCCCCTTTCCGCCTCAAGGGCCATCCAAAGAAGTGCGGTGATGGCAGATTTGAGTTAGCCTGCGAAAACAATGTGACCTCCATCTC...

Protein

3 records

下载 Protein FASTA

XP_057803919.1
MLLVQNQLIPSHTMITQNPIFLTISSLLILSLLNNLFQTCVANSYCSPSACGIFPNISSPFRLKGHPKKCGDGRFELACENNVTSISLNSHKYYVKAINYSNSAIRLVDASINNHDICSFPTLFDFSIDPRFYFYVTRYSNSPINFISCPNQLTNSSLFTDITTQCASNSSHPRYAYIKVGHMTASELPYSCGVDLIVMTSWQEFKDFNNVSLSEIHQSLLYGLELYFCTQSWCGSSTKLNWENFKRQLFSNRLLLIPLA...

XP_057803920.1
MLLVQNQLIPSHTMITQNPIFLTISSLLILSLLNNLFQTCVANSYCSPSACGIFPNISSPFRLKGHPKKCGDGRFELACENNVTSISLNSHKYYVKAINYSNSAIRLVDASINNHDICSFPTLFDFSIDPRFYFYVTRYSNSPINFISCPNQLTNSSLFTDITTQCASNSSHPRYAYIKVGHMTASELPYSCGVDLIVMTSWQEFKDFNNVSLSEIHQSLLYGLELYFCTQSWCGSSTKLNWGLLLIPLALLVRGVESTK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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