Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G001654`

染色体: Chr01 坐标: 30601165-30605084 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G001654`
名称	SmilChr01G001654
描述	leucine-rich repeat receptor-like protein kinase PEPR2
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	30601165 - 30605084 / `-`

ID 对照

NCBI Gene ID	`LOC131019668`
GeneID	`131019668`
locus_tag	`-`
NCBI Name	`LOC131019668`
原始查询	`LOC131019668`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	leucine-rich repeat receptor-like protein kinase PEPR2
产物	leucine-rich repeat receptor-like protein kinase PEPR2
Arabidopsis	`AT1G73080` (PEPR1) PEP1 receptor 1 [Source:NCBI gene (formerly Entrezgene);Acc:843639] identity=37; qcov=0.966; evalue=0; confidence=medium
Rice	`Os10g0155700` - identity=46; qcov=0.814; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	smil00230 (Purine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:131019668

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057804245.1`
2	Nucleus	细胞核	0.00000	`XP_057804245.1`
3	Chromosome	染色体	0.00000	`XP_057804245.1`
4	Centromere	着丝粒	0.00000	`XP_057804245.1`
5	Chromatin	染色质	0.00000	`XP_057804245.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:30601358`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B40
`Chr1:30601881`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A25
`Chr1:30601884`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B93
`Chr1:30602027`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B40
`Chr1:30602115`	`A`	`AT`	1bp_insertion	frameshift_variant	4	A10,A25,B122,D9
`Chr1:30602115`	`A`	`AT`	1bp_insertion	CDS_variant	4	A10,A25,B122,D9
`Chr1:30602322`	`A`	`AAT`	2bp_insertion	frameshift_variant	23	A1,A19,A25,B107,B115,B119,B13,B132,B18,B2,B23,B34,B37,B42,B43,B5,B7,C1,C31,C41,C70,C74,D8
`Chr1:30602323`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C74
`Chr1:30602323`	`TC`	`T`	1bp_deletion	CDS_variant	1	C74
`Chr1:30602326`	`TCG`	`T`	2bp_deletion	frameshift_variant	23	A1,A19,A25,B107,B115,B119,B13,B132,B18,B2,B23,B34,B37,B42,B43,B5,B7,C1,C31,C41,C70,C74,D8
`Chr1:30602339`	`G`	`A`	EMS_canonical_SNV	stop_gained	104	A10,A11,A13,A14,A15,A16,A18,A19,A2,A24,A25,A4,A6,A7,A9,B10,B100,B105,B107,B109,B11,B110,B111,B113,B114,B115,B118,B119,B12,B120,B122,B127,B128,B129,B13,B132,B134,B136,B15,B16,B18,B2,B20,B23,B29,B3,B30,B33,B34,B35,B37,B42,B43,B45,B48,B51,B62,B63,B65,B67,B68,B7,B70,B71,B76,B8,B81,B83,B86,B87,B9,B90,C1,C11,C13,C14,C2,C21,C23,C24,C25,C28,C3,C32,C33,C41,C42,C45,C5,C54,C55,C58,C62,C65,C66,C70,C71,C74,C76,C81,D10,D11,D6,D8
`Chr1:30602354`	`CCT`	`C`	2bp_deletion	frameshift_variant	19	A13,A8,B10,B100,B110,B122,B128,B136,B16,B33,B70,C14,C2,C23,C3,C58,C66,C74,D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804245.1

1135 aa

568

1135

LRRNT_2

LRR_1

LRR_8

LRR_1

LRR_8

LRR_1

LRR_8

LRR_1

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 27-62 aa PF00560 LRR_1 169-188 aa PF13855 LRR_8 241-299 aa PF00560 LRR_1 265-287 aa PF00560 LRR_1 289-311 aa PF00560 LRR_1 313-335 aa PF00560 LRR_1 337-359 aa PF00560 LRR_1 507-528 aa PF13855 LRR_8 533-590 aa PF00560 LRR_1 555-577 aa PF00560 LRR_1 579-599 aa PF13855 LRR_8 627-686 aa PF00560 LRR_1 677-697 aa PF00560 LRR_1 700-717 aa PF00560 LRR_1 725-743 aa PF00069 Pkinase 847-1114 aa PF07714 PK_Tyr_Ser-Thr 850-1116 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804245.1`	Pfam	`PF08263`	LRRNT_2	Family	27	62	4.9e-07	30.6	Leucine rich repeat N-terminal domain
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	169	188	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF13855`	LRR_8	Repeat	241	299	1.6e-54	182.2	Leucine rich repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	265	287	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	289	311	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	313	335	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	337	359	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	507	528	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF13855`	LRR_8	Repeat	533	590	1.6e-54	182.2	Leucine rich repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	555	577	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	579	599	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF13855`	LRR_8	Repeat	627	686	1.6e-54	182.2	Leucine rich repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	677	697	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	700	717	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00560`	LRR_1	Repeat	725	743	2e-63	197.2	Leucine Rich Repeat
`XP_057804245.1`	Pfam	`PF00069`	Pkinase	Domain	847	1114	1.5e-45	156.4	Protein kinase domain
`XP_057804245.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	850	1116	1.4e-38	133.4	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057948262.1
AATATAAAATTGACAAGATGCCGCACATGGGCAGCTTATAAAGTTATTCTAATGTGGTAGTGGGTAGTTATCACTTGAGCAGCTCTTCTTGGACCGACAGCATTACTATTTACTACAACAAACATATGCCCATTTTCTCAACTCAAAGCAGCCTAGCTTCTAAAATATTCAAAACCACACATGTAGCCGCGCTTCTTCATCACATGATCCATTACCATTTTTGCCAAAAACAATCCAACACAACACTCGAATTCTAAATC...

CDS

1 records

下载 CDS FASTA

LOC131019668
ATGTTACCATTTCTGTTTTTTTGTTATGTTCTGCTCCTTGTCCCAATCCCATCTGCTTCGCAGCCTCAAGCTGCGCTGCAGCTTCTCCGCTTTCGAAACAGTCTGCCGGAGGCCTCAAAATCTCTCCTGCAATGGAACCAAACCACCTCATCCTCTGCTCACTGCACCTGGCCTGGTGTTTCTTGCTACTCAAACGAAACAGATTTTCGTGTGGAGAGGTTGAAGCTAACGGGCTTCGGCCTCACTGGGGTTCTAGAGGA...

Protein

1 records

下载 Protein FASTA

XP_057804245.1
MLPFLFFCYVLLLVPIPSASQPQAALQLLRFRNSLPEASKSLLQWNQTTSSSAHCTWPGVSCYSNETDFRVERLKLTGFGLTGVLEESFPYLCELPDLILVDLQGNNFSGSVPAVLGNCSHLNHVNLKSNNLSGPIPPHLFKPGKLIALNLGRNKLSGTIPPEVGLCRRLEYLSLEENSFTGGIPTELFTISSLIYLSLNLNKLNGSLPDLPSPCSLVELQLTENSFHGGLPSSIRNCHDLQVLIASFNHLGGVMQQDIF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器