Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G001585`

染色体: Chr04 坐标: 26342507-26355706 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G001585`
名称	SmilChr04G001585
描述	clathrin heavy chain 1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	26342507 - 26355706 / `+`

ID 对照

NCBI Gene ID	`LOC131020018`
GeneID	`131020018`
locus_tag	`-`
NCBI Name	`LOC131020018`
原始查询	`LOC131020018`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	clathrin heavy chain 1-like
产物	clathrin heavy chain 1-like
Arabidopsis	`AT3G11130` (AT3G11130) Clathrin, heavy chain [Source:NCBI gene (formerly Entrezgene);Acc:820284] identity=92.7; qcov=0.971; evalue=0; confidence=high
Rice	`Os11g0104900` - identity=92; qcov=0.971; evalue=0; confidence=high
GO	GO:0005198 (structural molecule activity); GO:0005794 (Golgi apparatus); GO:0005886 (plasma membrane); GO:0006886 (intracellular protein transport); GO:0006898 (receptor-mediated endocytosis); GO:0009506 (plasmodesma); GO:0009507 (chloroplast); GO:0030130 (clathrin coat of trans-Golgi network vesicle); GO:0030132 (clathrin coat of coated pit); GO:0032051 (clathrin light chain binding); GO:0071439 (clathrin complex)
KEGG	smil04142 (Lysosome biogenesis - Salvia miltiorrhiza (redroot sage)); smil04144 (Endocytosis - Salvia miltiorrhiza (redroot sage)); smil05100 (Bacterial invasion of epithelial cells - Salvia miltiorrhiza (redroot sage))
Pfam	PF00637 (Clathrin); PF01394 (Clathrin_propel); PF09268 (Clathrin-link); PF13838 (Clathrin_H_link)
InterPro	-
eggNOG	-
NR	GeneID:131020018

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	0.80000	`XP_057804631.1`
2	Cytosol	细胞质基质	0.80000	`XP_057804631.1`
3	Cytoplasmic vesicle	细胞质囊泡	0.60000	`XP_057804631.1`
4	Endocytic vesicle	Endocytic vesicle	0.60000	`XP_057804631.1`
5	Clathrin-coated vesicle	Clathrin-coated vesicle	0.60000	`XP_057804631.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:26344326`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr4:26344434`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D7
`Chr4:26344467`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C64
`Chr4:26344546`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B131
`Chr4:26346422`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B95
`Chr4:26346563`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:26346577`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B123,B14,B44,C67
`Chr4:26346625`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A13,B104,B25,C13
`Chr4:26346848`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B33
`Chr4:26346865`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D3
`Chr4:26346992`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B42,B43
`Chr4:26347321`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B91,D10

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804631.1

1731 aa

866

1731

Clathrin_propel

Clathrin-link

Clathrin_H_link

Clathrin

PF01394 Clathrin_propel 20-55 aa PF01394 Clathrin_propel 155-197 aa PF09268 Clathrin-link 344-367 aa PF13838 Clathrin_H_link 369-434 aa PF00637 Clathrin 557-659 aa PF00637 Clathrin 726-866 aa PF00637 Clathrin 875-1006 aa PF00637 Clathrin 1018-1156 aa PF00637 Clathrin 1169-1306 aa PF00637 Clathrin 1313-1457 aa PF00637 Clathrin 1463-1604 aa

XP_057804632.1

1706 aa

853

1706

Clathrin_propel

Clathrin-link

Clathrin_H_link

Clathrin

PF01394 Clathrin_propel 20-55 aa PF01394 Clathrin_propel 155-197 aa PF09268 Clathrin-link 344-367 aa PF13838 Clathrin_H_link 369-434 aa PF00637 Clathrin 557-692 aa PF00637 Clathrin 701-841 aa PF00637 Clathrin 850-981 aa PF00637 Clathrin 993-1131 aa PF00637 Clathrin 1144-1281 aa PF00637 Clathrin 1288-1432 aa PF00637 Clathrin 1438-1579 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804631.1`	Pfam	`PF01394`	Clathrin_propel	Repeat	20	55	1.7e-33	113.8	Clathrin propeller repeat
`XP_057804631.1`	Pfam	`PF01394`	Clathrin_propel	Repeat	155	197	1.7e-33	113.8	Clathrin propeller repeat
`XP_057804631.1`	Pfam	`PF09268`	Clathrin-link	Repeat	344	367	7.6e-09	35.5	Clathrin, heavy-chain linker
`XP_057804631.1`	Pfam	`PF13838`	Clathrin_H_link	Repeat	369	434	9.5e-29	99.9	Clathrin-H-link
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	557	659	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	726	866	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	875	1006	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	1018	1156	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	1169	1306	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	1313	1457	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804631.1`	Pfam	`PF00637`	Clathrin	Repeat	1463	1604	1.9e-212	696.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF01394`	Clathrin_propel	Repeat	20	55	1.6e-33	113.9	Clathrin propeller repeat
`XP_057804632.1`	Pfam	`PF01394`	Clathrin_propel	Repeat	155	197	1.6e-33	113.9	Clathrin propeller repeat
`XP_057804632.1`	Pfam	`PF09268`	Clathrin-link	Repeat	344	367	7.4e-09	35.5	Clathrin, heavy-chain linker
`XP_057804632.1`	Pfam	`PF13838`	Clathrin_H_link	Repeat	369	434	9e-29	100.0	Clathrin-H-link
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	557	692	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	701	841	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	850	981	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	993	1131	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	1144	1281	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	1288	1432	1.6e-215	706.3	Region in Clathrin and VPS
`XP_057804632.1`	Pfam	`PF00637`	Clathrin	Repeat	1438	1579	1.6e-215	706.3	Region in Clathrin and VPS

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057948648.1
TTTAGATCTCCCTCCCTCACTATTTTTCATTTTCCGACTCAGCAAAATTCCATTTTCGCTGTCGCATTTGCGTCTATATATAATACTGTACACTTCTTTACTTAGTTTCTTCTGCCTTTAGAAGAACCCCCCCTCTCTCTCTCTCTAGATCTTCTGTTTCTCTTCGGTTAGAGGGTACGAGGGTTTCTCCTTGCTTTCCAGATCTCGAGAACATCTGTGATACGCCGTCGTCCTTGGCTTAGATCCGCAGCTTCGATCTC...

XM_057948649.1
TTAGATCTCCCTCCCTCACTATTTTTCATTTTCCGACTCAGCAAAATTCCATTTTCGCTGTCGCATTTGCGTCTATATATAATACTGTACACTTCTTTACTTAGTTTCTTCTGCCTTTAGAAGAACCCCCCCTCTCTCTCTCTCTAGATCTTCTGTTTCTCTTCGGTTAGAGGGTACGAGGGTTTCTCCTTGCTTTCCAGATCTCGAGAACATCTGTGATACGCCGTCGTCCTTGGCTTAGATCCGCAGCTTCGATCTCG...

CDS

2 records

下载 CDS FASTA

LOC131020018
ATGGCGGCTGCCAATGCTCCGATCACCATGAAAGAAGCGCTTACGTTGACTAGCTTAGGGATCAATCCCCAGTTCATTACTTTTACAAATGTGACGATGGAATCTGATAAGTACATCTGTGTTCGTGAGACTGCTCCACAAAACAGCGTGGTGATTATCGATATGAGCATGCCATCACAACCACTTCGGCGGCCCATTACAGCCGATTCAGCACTTATGAATCCAAATTCTAGAATTTTGGCATTGAAAGCTCAACTTCC...

Protein

2 records

下载 Protein FASTA

XP_057804631.1
MAAANAPITMKEALTLTSLGINPQFITFTNVTMESDKYICVRETAPQNSVVIIDMSMPSQPLRRPITADSALMNPNSRILALKAQLPGTTQDHLQIFNIEAKAKMKSHQMPEQVVFWKWITPKMLGLVTQSSVYHWSIEGDSEPVKMFDRTANLANNQIINYKCDPSEKWLVLIGIAPGSPERPQLVKGNMQLFSVDQQRSQALEAHAASFASFKIAGNDKDSILISFASKSSNAGQVTSKLHVIELGAQPGKPSFTKKQ...

XP_057804632.1
MAAANAPITMKEALTLTSLGINPQFITFTNVTMESDKYICVRETAPQNSVVIIDMSMPSQPLRRPITADSALMNPNSRILALKAQLPGTTQDHLQIFNIEAKAKMKSHQMPEQVVFWKWITPKMLGLVTQSSVYHWSIEGDSEPVKMFDRTANLANNQIINYKCDPSEKWLVLIGIAPGSPERPQLVKGNMQLFSVDQQRSQALEAHAASFASFKIAGNDKDSILISFASKSSNAGQVTSKLHVIELGAQPGKPSFTKKQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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