Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003278`

染色体: Chr04 坐标: 49467144-49471918 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003278`
名称	SmilChr04G003278
描述	acetolactate synthase 1, chloroplastic-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	49467144 - 49471918 / `-`

ID 对照

NCBI Gene ID	`LOC131020176`
GeneID	`131020176`
locus_tag	`-`
NCBI Name	`LOC131020176`
原始查询	`LOC131020176`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	acetolactate synthase 1, chloroplastic-like
产物	acetolactate synthase 1%2C chloroplastic-like
Arabidopsis	`AT3G48560` (CSR1) chlorsulfuron/imidazolinone resistant 1 [Source:NCBI gene (formerly Entrezgene);Acc:824015] identity=82.9; qcov=0.895; evalue=0; confidence=high
Rice	`Os02g0510200` (ALS) - identity=77.6; qcov=0.886; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0003984 (acetolactate synthase activity); GO:0005948 (acetolactate synthase complex); GO:0009097 (GO:0009097); GO:0009099 (L-valine biosynthetic process); GO:0030976 (thiamine pyrophosphate binding); GO:0050660 (flavin adenine dinucleotide binding)
KEGG	smil00290 (Valine, leucine and isoleucine biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00650 (Butanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00660 (C5-Branched dibasic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil00770 (Pantothenate and CoA biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00205 (TPP_enzyme_M); PF02775 (TPP_enzyme_C); PF02776 (TPP_enzyme_N)
InterPro	-
eggNOG	-
NR	GeneID:131020176

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057804849.1`
2	Chloroplast stroma	叶绿体基质	0.40000	`XP_057804849.1`
3	Mitochondrion	线粒体	0.20000	`XP_057804849.1`
4	Nucleus	细胞核	0.00000	`XP_057804849.1`
5	Chromosome	染色体	0.00000	`XP_057804849.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:49469776`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A3,B46
`Chr4:49469902`	`AGC`	`A`	2bp_deletion	frameshift_variant	1	B35
`Chr4:49469902`	`AGC`	`A`	2bp_deletion	CDS_variant	1	B35
`Chr4:49469948`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B100
`Chr4:49470035`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B44,C50
`Chr4:49470329`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B130,B63,C12,C53
`Chr4:49470344`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B131,B21,B54,C15
`Chr4:49470582`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr4:49470989`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C84
`Chr4:49471106`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B52
`Chr4:49471121`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A3,B46
`Chr4:49471178`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C84

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804849.1

659 aa

330

659

TPP_enzyme_N

TPP_enzyme_M

TPP_enzyme_C

PF02776 TPP_enzyme_N 83-193 aa PF00205 TPP_enzyme_M 274-408 aa PF02775 TPP_enzyme_C 473-628 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804849.1`	Pfam	`PF02776`	TPP_enzyme_N	Domain	83	193	3.3e-37	127.6	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
`XP_057804849.1`	Pfam	`PF00205`	TPP_enzyme_M	Domain	274	408	5.1e-42	143.5	Thiamine pyrophosphate enzyme, central domain
`XP_057804849.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	473	628	2.1e-51	174.4	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057948866.1
TTCTAGCTCGGCTTGCATCATCGAGCTTCCAGGCACGGCAGTGTGGTGGGACTCGCCGAGGGCCGGCTCGAGGCTCTCGGTCGACCCCGCTGGAGGCTCTCATGTGCAATGACCCACTACTCTCATCACCAATTAACCGCCACCACATAAAGTTGAGGTTGTTGAGAAACAACATAATTTGTTGATTAGGGGCATTTTCCGCCATTGGCGCCTCGATAAGATTTTGCCCCGCAAATCTAACGTACCTCCTTCTACTCCCC...

CDS

1 records

下载 CDS FASTA

LOC131020176
ATGGCGGCCTCCGCTCCGACCCCCACGTCCTTCAAACCCTCCCAGGAGCCTTCTGTGTCCAATTCGCCGAAGCTTCTTTCCAGATTCACCCTCCCTTTCCCTCACAATCCCCAAAAGCCGCCAGCCGCCCCCGCCATTTCCCTCCGCCGGCCCCTCCAAAATTTGAATGTGTTAACTTCTCCCGACAAACAAGTTCTCCAAGAGGAGGAGACGTTCGTCTCCCGGTTCGCTCCAGATGAACCTCGAAAGGGCTGCGACGT...

Protein

1 records

下载 Protein FASTA

XP_057804849.1
MAASAPTPTSFKPSQEPSVSNSPKLLSRFTLPFPHNPQKPPAAPAISLRRPLQNLNVLTSPDKQVLQEEETFVSRFAPDEPRKGCDVLVEALEREGVTDVFAYPGGASMEIHQALTRSNTIRNVLPRHEQGGVFAAEGYARASGRPGVCIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVLDVEDIPRIVREAFFIARSGRPGPVLIDVPKDIQQQMVVPNWDQPMRLGG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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