Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003803`

染色体: Chr04 坐标: 54194316-54196224 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003803`
名称	SmilChr04G003803
描述	glyoxylate/hydroxypyruvate reductase HPR3-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	54194316 - 54196224 / `+`

ID 对照

NCBI Gene ID	`LOC131020696`
GeneID	`131020696`
locus_tag	`-`
NCBI Name	`LOC131020696`
原始查询	`LOC131020696`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	glyoxylate/hydroxypyruvate reductase HPR3-like
产物	glyoxylate/hydroxypyruvate reductase HPR3-like
Arabidopsis	`AT2G45630` (AT2G45630) D-isomer specific 2-hydroxyacid dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:819171] identity=55.2; qcov=0.959; evalue=8.77e-124; confidence=high
Rice	`Os04g0107200` - identity=56; qcov=0.893; evalue=2.6e-104; confidence=high
GO	GO:0005829 (cytosol); GO:0016618 (hydroxypyruvate reductase [NAD(P)H] activity); GO:0030267 (glyoxylate reductase (NADPH) activity); GO:0051287 (NAD binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00389 (2-Hacid_dh); PF02826 (2-Hacid_dh_C); PF03446 (NAD_binding_2)
InterPro	-
eggNOG	-
NR	GeneID:131020696

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057805667.1`
2	Cytoplasm	细胞质	0.60000	`XP_057805667.1`
3	Mitochondrion	线粒体	0.20000	`XP_057805667.1`
4	Mitochondrion matrix	线粒体基质	0.20000	`XP_057805667.1`
5	Nucleus	细胞核	0.00000	`XP_057805667.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:54194468`	`CA`	`C`	1bp_deletion	frameshift_variant	133	A11,A16,A18,A19,A21,A25,A3,A4,A6,A7,A8,A9,B1,B106,B107,B108,B109,B11,B110,B111,B112,B115,B118,B119,B120,B122,B123,B125,B126,B127,B129,B135,B136,B137,B138,B140,B16,B17,B18,B19,B2,B22,B26,B29,B3,B30,B33,B34,B35,B36,B45,B49,B51,B52,B54,B55,B56,B58,B61,B62,B63,B64,B65,B66,B68,B73,B76,B77,B78,B79,B80,B86,B87,B9,B91,B95,B96,B97,B99,C10,C11,C12,C15,C17,C19,C24,C26,C27,C29,C3,C31,C32,C34,C39,C4,C40,C41,C42,C44,C46,C48,C5,C50,C52,C56,C57,C59,C6,C61,C63,C68,C69,C7,C70,C72,C74,C75,C76,C77,C78,C81,C82,C83,C85,C86,C87,C9,D10,D2,D3,D6,D7,D9
`Chr4:54194650`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B133
`Chr4:54194802`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A25,B107
`Chr4:54194841`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B1,B129,B136,B68
`Chr4:54194888`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C6
`Chr4:54194928`	`CT`	`C`	1bp_deletion	frameshift_variant	100	A10,A13,A19,A25,A3,A5,A6,B1,B10,B100,B102,B103,B11,B113,B114,B115,B119,B121,B122,B123,B129,B136,B14,B140,B16,B24,B25,B26,B27,B29,B3,B30,B39,B4,B41,B42,B43,B45,B46,B48,B5,B52,B6,B61,B64,B66,B67,B68,B70,B72,B73,B75,B78,B80,B81,B84,B85,B90,B92,B95,B97,B99,C10,C13,C17,C2,C21,C22,C24,C28,C3,C33,C34,C38,C39,C40,C41,C44,C48,C52,C53,C54,C55,C56,C62,C64,C65,C66,C67,C75,C76,C79,C81,C83,C86,C87,D4,D7,D8,D9
`Chr4:54195700`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B41
`Chr4:54195718`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C35
`Chr4:54195727`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr4:54195728`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B68
`Chr4:54195742`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C35
`Chr4:54195821`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B127,B29,B54

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805667.1

338 aa

169

338

2-Hacid_dh

2-Hacid_dh_C

NAD_binding_2

PF00389 2-Hacid_dh 58-334 aa PF02826 2-Hacid_dh_C 130-304 aa PF03446 NAD_binding_2 169-264 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805667.1`	Pfam	`PF00389`	2-Hacid_dh	Domain	58	334	3.4e-17	63.1	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
`XP_057805667.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	130	304	2e-50	171.3	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057805667.1`	Pfam	`PF03446`	NAD_binding_2	Domain	169	264	5.9e-05	23.9	NAD binding domain of 6-phosphogluconate dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057949684.1
AATACATAATAAAATTAAAGTACTAGATTATCCATGCATTATAGTTGCAGCTGTTGTGGAATGAATCTCCTCATATGTTTAGCTTCTAATTTCTACTCCTAATTTCACAAAGCCCTAATCCGACTATATCAGAACCCCCATGCGATTAGTTCCAAAAAAAAATATGGGTGAAAATCAGCCGTCCTCCGCCGCTCAGCAGTCGCCGGAAATCATAATCCTCGGCCCGCCGTCCGTTTTCCGAGTATACGAGAAAGAATTTA...

CDS

1 records

下载 CDS FASTA

LOC131020696
ATGCGATTAGTTCCAAAAAAAAATATGGGTGAAAATCAGCCGTCCTCCGCCGCTCAGCAGTCGCCGGAAATCATAATCCTCGGCCCGCCGTCCGTTTTCCGAGTATACGAGAAAGAATTTAGTTCGAGATTCCGAGTTTTGAGGCCATGGGAATCGCAGGTGCCCCTGCCCCAATTCCTAGCTGCCCGGGCCCACGGCACGCGGGCCGCCGTCTGCAGCGGCGATTTCCAGCTCTCCGCCGCGGTTCTCGGCAATTTACC...

Protein

1 records

下载 Protein FASTA

XP_057805667.1
MRLVPKKNMGENQPSSAAQQSPEIIILGPPSVFRVYEKEFSSRFRVLRPWESQVPLPQFLAARAHGTRAAVCSGDFQLSAAVLGNLPSLRLVFTTSAGLNHIDLTECRRRGIAVAYAGNFFSADVADLAVGLLLDVLRKVSAGNRFVKNRLWPHPPDSFPLGSKLGGKRVGIVGLGSIGVEVAKRLEAFGCTISYCSRKKKPLAPYTSYPDIHELASNSDVLVLCCALTEQTRHMINREVMLALGKGGVIVNIARGAVID...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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