Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003983`

染色体: Chr04 坐标: 55267589-55277119 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003983`
名称	SmilChr04G003983
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 1
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	55267589 - 55277119 / `+`

ID 对照

NCBI Gene ID	`LOC131020848`
GeneID	`131020848`
locus_tag	`-`
NCBI Name	`LOC131020848`
原始查询	`LOC131020848`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 1
产物	brefeldin A-inhibited guanine nucleotide-exchange protein 1
Arabidopsis	`AT4G38200` (AT4G38200) SEC7-like guanine nucleotide exchange family protein [Source:NCBI gene (formerly Entrezgene);Acc:829976] identity=66; qcov=1.01; evalue=0; confidence=high
Rice	`Os06g0622800` - identity=57.6; qcov=0.404; evalue=0; confidence=low
GO	GO:0005085 (guanyl-nucleotide exchange factor activity); GO:0005802 (trans-Golgi network); GO:0032012 (regulation of ARF protein signal transduction)
KEGG	smil04144 (Endocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF01369 (Sec7); PF09324 (Sec7-like_HDS); PF12783 (Sec7-like_HUS); PF16206 (Mon2_C); PF16213 (DCB); PF20252 (BIG2_C)
InterPro	-
eggNOG	-
NR	GeneID:131020848

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	0.80000	`XP_057805875.1`
2	Cytosol	细胞质基质	0.40000	`XP_057805875.1`
3	Trans-golgi network	Trans-golgi network	0.40000	`XP_057805875.1`
4	Nucleus	细胞核	0.00000	`XP_057805875.1`
5	Chromosome	染色体	0.00000	`XP_057805875.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:55268237`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B4
`Chr4:55268239`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B84
`Chr4:55268479`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B84,B95
`Chr4:55268482`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B44,B69,C17,C79
`Chr4:55268542`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B4
`Chr4:55268692`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B42
`Chr4:55268837`	`GA`	`G`	1bp_deletion	frameshift_variant	1	B43
`Chr4:55268837`	`GA`	`G`	1bp_deletion	CDS_variant	1	B43
`Chr4:55269646`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B44,B69,C17,C79
`Chr4:55271181`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B108,B118,C22,C56
`Chr4:55271263`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B82
`Chr4:55272184`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B58,C62

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805875.1

1698 aa

849

1698

DCB

Sec7-like_HUS

Sec7

Sec7-like_HDS

Mon2_C

BIG2_C

PF16213 DCB 21-201 aa PF12783 Sec7-like_HUS 287-445 aa PF01369 Sec7 554-735 aa PF09324 Sec7-like_HDS 1102-1184 aa PF16206 Mon2_C 1205-1331 aa PF20252 BIG2_C 1494-1689 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805875.1`	Pfam	`PF16213`	DCB	Repeat	21	201	7.6e-25	88.4	Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain
`XP_057805875.1`	Pfam	`PF12783`	Sec7-like_HUS	Repeat	287	445	2.2e-40	138.8	Mon2/Sec7/BIG1-like, HUS domain
`XP_057805875.1`	Pfam	`PF01369`	Sec7	Domain	554	735	1.2e-75	253.9	Sec7 domain
`XP_057805875.1`	Pfam	`PF09324`	Sec7-like_HDS	Domain	1102	1184	2e-34	118.0	Mon2/Sec7/BIG1-like, HDS
`XP_057805875.1`	Pfam	`PF16206`	Mon2_C	Repeat	1205	1331	8e-08	31.6	C-terminal region of Mon2 protein
`XP_057805875.1`	Pfam	`PF20252`	BIG2_C	Domain	1494	1689	4.8e-33	115.4	BIG2 C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057949892.1
GTTGGATTTGGTCCGATTTAATTAAGCAAAAGAAATTAAAAACGCACACGCAAATAAAAATAAAAATAAAAATAAAAAAAGACCGACGACAGAGAAGAAGAGAAATCGGAAAGCAATCGATCCGATTTAAGTGAGGAAGCAGTGGAATTGCTTCTGATTCACGACGACTGTTAATCGCCTGTGTCGGTCGCCACTGTCCTCGTCTCAGATTCGCTCCACTCAAATCCACCTGCTTCGAGCTCGAGATTTAGGGAATTATC...

CDS

1 records

下载 CDS FASTA

LOC131020848
ATGTCGGCGTCTCAAACCCTAGGCGGGGCTTCCCGCTGCGGGTGGGTGCTGGGGCCCTCGCTGGACAAGATCATCAAAAATGTGGCGTGGAGGAAGCACTCGCAGCTCGTTTCCGCCTGCAAATCTGTTCTCGACAAGCTCGAGGCTCTCGCCGACGAGCCCTCCGATCCGGCCTCCTGCACCCCTCTCTACGGCCTCTCTTCTTCCGATGCCGAATTCCTGCTCCAGCCACTCATCGCGGCGCTCGAATCGGGCTACCC...

Protein

1 records

下载 Protein FASTA

XP_057805875.1
MSASQTLGGASRCGWVLGPSLDKIIKNVAWRKHSQLVSACKSVLDKLEALADEPSDPASCTPLYGLSSSDAEFLLQPLIAALESGYPKVVEPALDCAFRLFSFGLVRGCEIREDASVIFRLIDSVCKCAAIADEAIELAVLKVLLSAVRSPCIDIRGDCLIYIVRSCYNVYLGGHSGTNQICAKAVLAQMMIVIFTRTEENSMLVDVKNVSVFELLEFADRNLNEGSSIHFAQTFINEIMECKDSPLIAKSPMELQNGSK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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