Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002119`

染色体: Chr04 坐标: 34177739-34181453 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002119`
名称	SmilChr04G002119
描述	5-formyltetrahydrofolate cyclo-ligase, mitochondrial-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	34177739 - 34181453 / `-`

ID 对照

NCBI Gene ID	`LOC131021279`
GeneID	`131021279`
locus_tag	`-`
NCBI Name	`LOC131021279`
原始查询	`LOC131021279`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	5-formyltetrahydrofolate cyclo-ligase, mitochondrial-like
产物	5-formyltetrahydrofolate cyclo-ligase%2C mitochondrial-like
Arabidopsis	`AT5G13050` (5-FCL) 5-formyltetrahydrofolate cycloligase [Source:NCBI gene (formerly Entrezgene);Acc:831144] identity=65.7; qcov=0.9; evalue=2.71e-106; confidence=high
Rice	`Os07g0578600` - identity=63.8; qcov=0.851; evalue=6.22e-96; confidence=high
GO	GO:0005739 (mitochondrion); GO:0009396 (folic acid-containing compound biosynthetic process); GO:0030272 (5-formyltetrahydrofolate cyclo-ligase activity); GO:0035999 (tetrahydrofolate interconversion)
KEGG	smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil04981 (Folate transport and metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF01812 (5-FTHF_cyc-lig)
InterPro	-
eggNOG	-
NR	GeneID:131021279

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057806380.1`
2	Chloroplast	叶绿体	0.80000	`XP_057806380.1`
3	Mitochondrion matrix	线粒体基质	0.20000	`XP_057806380.1`
4	Nucleus	细胞核	0.00000	`XP_057806382.1`
5	Chromosome	染色体	0.00000	`XP_057806382.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:34177962`	`TG`	`T`	1bp_deletion	frameshift_variant	1	C6
`Chr4:34177962`	`TG`	`T`	1bp_deletion	CDS_variant	1	C6
`Chr4:34178248`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B110,B5
`Chr4:34179219`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B78,D4
`Chr4:34179681`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A22
`Chr4:34179693`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B41

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806380.1

283 aa

N

1

142

283

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 59-266 aa

XP_057806381.1

283 aa

N

1

142

283

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 59-266 aa

XP_057806382.1

269 aa

N

1

134

269

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 45-252 aa

XP_057806383.1

269 aa

N

1

134

269

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 45-252 aa

XP_057806384.1

269 aa

N

1

134

269

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 45-252 aa

XP_057806386.1

269 aa

N

1

134

269

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 45-252 aa

XP_057806387.1

269 aa

N

1

134

269

5-FTHF_cyc-lig

C

PF01812 5-FTHF_cyc-lig 45-252 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806380.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	59	266	7.7e-30	104.9	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806381.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	59	266	7.7e-30	104.9	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806382.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	45	252	6.6e-30	105.1	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806383.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	45	252	6.6e-30	105.1	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806384.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	45	252	6.6e-30	105.1	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806386.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	45	252	6.6e-30	105.1	5-formyltetrahydrofolate cyclo-ligase family
`XP_057806387.1`	Pfam	`PF01812`	5-FTHF_cyc-lig	Domain	45	252	6.6e-30	105.1	5-formyltetrahydrofolate cyclo-ligase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

7 records

下载 cDNA FASTA

XM_057950399.1
GTTTCAGAGAAAAGTCCTCGAATTGGGCCAATTACTAAATAAAAGCTTAGGCCTACTGCACGAAATGAATACTCGCGCCAGCCGCCGCCTTCTTCCGACGCAGCGTCGGTGACGCTTCCCCCGGCTCGCGTCAGCTCCACCCCGCTTCATTAAAGGTTTAATTAAAACAGCCCGCCGAGCGCCCCCCCCCCCCCCCCCCCCCCCCCAACACCGGTCAGACGATTCGGAATCTCAGATCAGGATAAGATTTGCAGAGCGGA...

XM_057950400.1
GTTTCAGAGAAAAGTCCTCGAATTGGGCCAATTACTAAATAAAAGCTTAGGCCTACTGCACGAAATGAATACTCGCGCCAGCCGCCGCCTTCTTCCGACGCAGCGTCGGTGACGCTTCCCCCGGCTCGCGTCAGCTCCACCCCGCTTCATTAAAGGTTTAATTAAAACAGCCCGCCGAGCGCCCCCCCCCCCCCCCCCCCCCCCCCAACACCGGTCAGACGATTCGGAATCTCAGATCAGGATAAGGTCGCCGCCTACAA...

CDS

7 records

下载 CDS FASTA

LOC131021279
ATGACGATAATAGGTCGCCGCCTACAAAGATTTGCAGAGCGGATGATACTGCAGCTCGCTTTACCAACCGCCGCAACGCCTGCTTTACCCACCACCTTATCCGGTCTGAATTTACGCTCCTCCGCTACCATGAGCGCCGGGGGTATCGCCGCCGCACCTCTAGACGCCGTTTTCAAGGAGAAAAAGGCGCTTCGCTCCAGAGTGAGAAAGGAACTCAAGTCAATGGACCCCGCGCTCAGATCTCAAGAAGATGATGCAAT...

LOC131021279
ATGACGATAATAGGTCGCCGCCTACAAAGATTTGCAGAGCGGATGATACTGCAGCTCGCTTTACCAACCGCCGCAACGCCTGCTTTACCCACCACCTTATCCGGTCTGAATTTACGCTCCTCCGCTACCATGAGCGCCGGGGGTATCGCCGCCGCACCTCTAGACGCCGTTTTCAAGGAGAAAAAGGCGCTTCGCTCCAGAGTGAGAAAGGAACTCAAGTCAATGGACCCCGCGCTCAGATCTCAAGAAGATGATGCAAT...

Protein

7 records

下载 Protein FASTA

XP_057806380.1
MTIIGRRLQRFAERMILQLALPTAATPALPTTLSGLNLRSSATMSAGGIAAAPLDAVFKEKKALRSRVRKELKSMDPALRSQEDDAIQRVVLEAPWFKSCTRLCAYISCAALREVDTSKVLSEILKNTAQDDHSQVRKKLYVPRVEDKNSFMRMLNITRMDDLIANSMDILEPQPCDAEGNEREDVMLADEPVDLFLLPGLAFDRSGRRIGRGGGYYDTFLTKYQELAKDRKWKKPLFVALSYSLQVLEDGVIPITPNDV...

XP_057806381.1
MTIIGRRLQRFAERMILQLALPTAATPALPTTLSGLNLRSSATMSAGGIAAAPLDAVFKEKKALRSRVRKELKSMDPALRSQEDDAIQRVVLEAPWFKSCTRLCAYISCAALREVDTSKVLSEILKNTAQDDHSQVRKKLYVPRVEDKNSFMRMLNITRMDDLIANSMDILEPQPCDAEGNEREDVMLADEPVDLFLLPGLAFDRSGRRIGRGGGYYDTFLTKYQELAKDRKWKKPLFVALSYSLQVLEDGVIPITPNDV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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