Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002412`

染色体: Chr04 坐标: 38746522-38749691 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002412`
名称	SmilChr04G002412
描述	probably inactive leucine-rich repeat receptor-like protein kinase IMK2
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	38746522 - 38749691 / `+`

ID 对照

NCBI Gene ID	`LOC131021540`
GeneID	`131021540`
locus_tag	`-`
NCBI Name	`LOC131021540`
原始查询	`LOC131021540`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probably inactive leucine-rich repeat receptor-like protein kinase IMK2
产物	probably inactive leucine-rich repeat receptor-like protein kinase IMK2
Arabidopsis	`AT3G51740` (IMK2) inflorescence meristem receptor-like kinase 2 [Source:NCBI gene (formerly Entrezgene);Acc:824337] identity=63; qcov=0.982; evalue=0; confidence=high
Rice	`Os12g0107700` - identity=59.3; qcov=0.895; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	-
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2); PF12799 (LRR_4); PF13516 (LRR_6); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:131021540

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057806757.1`
2	Nucleus	细胞核	0.00000	`XP_057806757.1`
3	Chromosome	染色体	0.00000	`XP_057806757.1`
4	Centromere	着丝粒	0.00000	`XP_057806757.1`
5	Chromatin	染色质	0.00000	`XP_057806757.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:38747200`	`TAA`	`T`	2bp_deletion	frameshift_variant	2	B51,B84
`Chr4:38747200`	`TAA`	`T`	2bp_deletion	CDS_variant	2	B51,B84
`Chr4:38747549`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B22,B53,B65
`Chr4:38747741`	`T`	`TTC`	2bp_insertion	frameshift_variant	2	B95,C82
`Chr4:38747741`	`T`	`TTC`	2bp_insertion	CDS_variant	2	B95,C82
`Chr4:38747742`	`CTG`	`C`	2bp_deletion	frameshift_variant	2	B95,C82
`Chr4:38747742`	`CTG`	`C`	2bp_deletion	CDS_variant	2	B95,C82
`Chr4:38747785`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B35,B36
`Chr4:38747860`	`T`	`TA`	1bp_insertion	frameshift_variant	4	B21,B3,B7,C70
`Chr4:38747860`	`T`	`TA`	1bp_insertion	CDS_variant	4	B21,B3,B7,C70
`Chr4:38747871`	`TCA`	`T`	2bp_deletion	frameshift_variant	3	B4,B7,C70
`Chr4:38747871`	`TCA`	`T`	2bp_deletion	CDS_variant	3	B4,B7,C70

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806757.1

784 aa

392

784

LRRNT_2

LRR_8

LRR_4

LRR_1

LRR_6

LRR_1

LRR_8

LRR_6

LRR_1

LRR_8

LRR_6

LRR_1

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 68-106 aa PF13855 LRR_8 134-193 aa PF12799 LRR_4 157-195 aa PF00560 LRR_1 158-180 aa PF13516 LRR_6 180-195 aa PF00560 LRR_1 183-203 aa PF00560 LRR_1 230-251 aa PF00560 LRR_1 253-275 aa PF13855 LRR_8 253-312 aa PF13516 LRR_6 277-289 aa PF00560 LRR_1 277-299 aa PF00560 LRR_1 301-323 aa PF13855 LRR_8 301-360 aa PF13516 LRR_6 323-339 aa PF00560 LRR_1 325-347 aa PF00560 LRR_1 349-369 aa PF00069 Pkinase 504-767 aa PF07714 PK_Tyr_Ser-Thr 505-769 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806757.1`	Pfam	`PF08263`	LRRNT_2	Family	68	106	2.5e-08	34.8	Leucine rich repeat N-terminal domain
`XP_057806757.1`	Pfam	`PF13855`	LRR_8	Repeat	134	193	2.6e-22	79.1	Leucine rich repeat
`XP_057806757.1`	Pfam	`PF12799`	LRR_4	Repeat	157	195	1.1e-19	70.7	Leucine Rich repeats (2 copies)
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	158	180	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF13516`	LRR_6	Repeat	180	195	1.2e-05	25.7	Leucine Rich repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	183	203	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	230	251	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	253	275	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF13855`	LRR_8	Repeat	253	312	2.6e-22	79.1	Leucine rich repeat
`XP_057806757.1`	Pfam	`PF13516`	LRR_6	Repeat	277	289	1.2e-05	25.7	Leucine Rich repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	277	299	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	301	323	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF13855`	LRR_8	Repeat	301	360	2.6e-22	79.1	Leucine rich repeat
`XP_057806757.1`	Pfam	`PF13516`	LRR_6	Repeat	323	339	1.2e-05	25.7	Leucine Rich repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	325	347	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF00560`	LRR_1	Repeat	349	369	1e-30	99.9	Leucine Rich Repeat
`XP_057806757.1`	Pfam	`PF00069`	Pkinase	Domain	504	767	1.7e-36	126.7	Protein kinase domain
`XP_057806757.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	505	769	7.5e-40	137.6	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057950774.1
AAAATGTGAAGAAATTTATTGAGGAAAATAATAAAGTTTGGAGGTGGAATAAGTCAAAGTTATTTAACGGTCGTCCGATCAATCACCAAACACAGAATATAGCTGTTATTGCCAATGAAGGACAGGTTTTTCAACCCCCAAAAACTAAAAAAAATAACCAACCTTAAAAAACATACAACTTCTGCAAACCAAGTAACTAGCCGTTGTGCTTTCAGACTAAGGAAAAAAGAAAAAGAAAAAAACATAACTAGCCGTTGCGA...

CDS

1 records

下载 CDS FASTA

LOC131021540
ATGATGGACGATCCAGTTCAATTGCGGCTCCATCATTTCAAAAATCTCTCGGCGGGAAATGCTGCATGGAGCTTGGGCTCAAACAAGAAGAGAGAGAAATGGAAGCCGGAGTTGGCCTTCCTCAGCCTCCTCCTCGCCCTCTTGTTTTCCGATTTCCGGCTCGTTTCCGGCGTCAAATGGGACGGCGTGATGGTGAGCCGAGCTGATTTCCAAGCCCTGCAGGCCATAAAAAAGGAATTGATCGACTTCAAAGGGGTGCT...

Protein

1 records

下载 Protein FASTA

XP_057806757.1
MMDDPVQLRLHHFKNLSAGNAAWSLGSNKKREKWKPELAFLSLLLALLFSDFRLVSGVKWDGVMVSRADFQALQAIKKELIDFKGVLRSWNDSGAGSCAGWIGIKCADGEVIAIQLPFKGLGGRISDRIGQLQSLRRLSLHDNVLVGPIPAALGFLPNLRGLYLFNNRLSGSVPQSISNCPLLQTLDLSNNQLTGVIPPNLANSTRFYRLNLSFNGISGSIPVSLSRSSSLNFLALQHNNLSGSLPDSWGSFQLKSLSLD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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