Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002833`

染色体: Chr04 坐标: 44441393-44446798 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002833`
名称	SmilChr04G002833
描述	NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	44441393 - 44446798 / `+`

ID 对照

NCBI Gene ID	`LOC131021904`
GeneID	`131021904`
locus_tag	`-`
NCBI Name	`LOC131021904`
原始查询	`LOC131021904`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial
产物	NADH dehydrogenase [ubiquinone] iron-sulfur protein 1%2C mitochondrial
Arabidopsis	`AT5G37510` (EMB1467) NADH-ubiquinone dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:833729] identity=78.7; qcov=1; evalue=0; confidence=high
Rice	`Os03g0713400` - identity=82.5; qcov=0.952; evalue=0; confidence=high
GO	GO:0008137 (NADH dehydrogenase (ubiquinone) activity); GO:0016020 (membrane); GO:0042773 (ATP synthesis coupled electron transport); GO:0051536 (iron-sulfur cluster binding)
KEGG	smil00190 (Oxidative phosphorylation - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF00111 (Fer2); PF00384 (Molybdopterin); PF09326 (NADH_dhqG_C); PF10588 (NADH-G_4Fe-4S_3); PF13510 (Fer2_4); PF22117 (Fer4_Nqo3); PF22151 (Fer4_NDSU1)
InterPro	-
eggNOG	-
NR	GeneID:131021904

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057807223.1`
2	Mitochondrion inner membrane	线粒体内膜	0.80000	`XP_057807223.1`
3	Mitochondrion membrane	线粒体膜	0.60000	`XP_057807223.1`
4	Nucleus	细胞核	0.00000	`XP_057807223.1`
5	Chromosome	染色体	0.00000	`XP_057807223.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:44441664`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B10
`Chr4:44441771`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B114,D7
`Chr4:44441773`	`GA`	`G`	1bp_deletion	frameshift_variant	1	C48
`Chr4:44441773`	`GA`	`G`	1bp_deletion	CDS_variant	1	C48
`Chr4:44441775`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C48
`Chr4:44441775`	`TC`	`T`	1bp_deletion	CDS_variant	1	C48
`Chr4:44441778`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr4:44441807`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B129,B140,B22,B41
`Chr4:44441905`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B75
`Chr4:44442831`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B104,B38,B39,C13
`Chr4:44444014`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B10
`Chr4:44444589`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807223.1

745 aa

372

745

Fer2_4

Fer2

NADH-G_4Fe-4S_3

Fer4_Nqo3

Fer4_NDSU1

Molybdopterin

NADH_dhqG_C

PF13510 Fer2_4 71-147 aa PF00111 Fer2 76-125 aa PF10588 NADH-G_4Fe-4S_3 154-191 aa PF22117 Fer4_Nqo3 207-273 aa PF22151 Fer4_NDSU1 286-336 aa PF00384 Molybdopterin 342-662 aa PF09326 NADH_dhqG_C 692-738 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807223.1`	Pfam	`PF13510`	Fer2_4	Domain	71	147	5.1e-20	72.0	2Fe-2S iron-sulfur cluster binding domain
`XP_057807223.1`	Pfam	`PF00111`	Fer2	Domain	76	125	4.8e-06	27.1	2Fe-2S iron-sulfur cluster binding domain
`XP_057807223.1`	Pfam	`PF10588`	NADH-G_4Fe-4S_3	Domain	154	191	7.8e-17	61.2	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
`XP_057807223.1`	Pfam	`PF22117`	Fer4_Nqo3	Domain	207	273	4.5e-33	114.0	NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
`XP_057807223.1`	Pfam	`PF22151`	Fer4_NDSU1	Domain	286	336	8.3e-30	102.8	NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
`XP_057807223.1`	Pfam	`PF00384`	Molybdopterin	Domain	342	662	5.3e-107	358.6	Molybdopterin oxidoreductase
`XP_057807223.1`	Pfam	`PF09326`	NADH_dhqG_C	Family	692	738	2.8e-14	54.2	NADH-ubiquinone oxidoreductase subunit G, C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057951240.1
TTGAATTAAAGCTAGGATGCAAATTTGAAAGCAAGTTGAAATGGAAGTGGAATACTTGGCTATGGCCTATGCTATGTGTAATAAAATGAAAACGGGCAAAACCCGTTGAGTTGATCCATAAAGAATCCGGATCTTCCTTCCTCCCCCTTTGAAATTGTGGACAACACAAGCGCACACAGCACTCCCACACTCCTCAACTCGGTGTCTCCCATCGTTAATCGTCTCAAATGGGGCTGACTCACCTCGCTTCTCGGGCCATT...

CDS

1 records

下载 CDS FASTA

LOC131021904
ATGGGGCTGACTCACCTCGCTTCTCGGGCCATTCTCCGATCCGCCCGCCTCGCCGCCTCCAACTCCCGCCATCAGCTCCGCCGCGCCATCGTCACCACGCCGGAGCTCCACAACTCTGCTGAAGCAGCTGCGGCGGATGCCCAGCCCGAGCCAGATCTCCCCAAGAGGAACCCTGTGGCCGGCGCCCGTGTCCATTTCCCCAATCCGGATGACGCAATCGAGGTCTTCGTCGATGGCTACCCGGTCAAAATCCCTAAGGG...

Protein

1 records

下载 Protein FASTA

XP_057807223.1
MGLTHLASRAILRSARLAASNSRHQLRRAIVTTPELHNSAEAAAADAQPEPDLPKRNPVAGARVHFPNPDDAIEVFVDGYPVKIPKGLTVLQACMLAGVDIPRFCYHDRLSIAGNCRMCLVEVEKSPKPVASCAMPALPGMKIKTDTPLAKKAREGVMEFLLMNHPLDCPICDQGGECDLQDQSMAFGSDRGRFTETKRSVVDKNLGPLVKTVMTRCIQCTRCVRFASEIAGVPDLGMLGRGSGEEIGTYVEKLMTSELS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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