当前解析结果
SmilChr04G000422| 统一新 Gene ID | SmilChr04G000422 |
|---|---|
| 名称 | SmilChr04G000422 |
| 描述 | DNA topoisomerase 2-like |
| 染色体 / SeqID | Chr04 / NC_080390.1 |
| 坐标与链方向 | 4481287 - 4487990 / - |
| NCBI Gene ID | LOC131022308 |
|---|---|
| GeneID | 131022308 |
| locus_tag | - |
| NCBI Name | LOC131022308 |
| 原始查询 | LOC131022308 |
| 来源 | GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog |
|---|---|
| 描述 | DNA topoisomerase 2-like |
| 产物 | DNA topoisomerase 2-like |
| Arabidopsis | AT3G23890 (TOPII)topoisomerase II [Source:NCBI gene (formerly Entrezgene);Acc:821972] identity=58.9; qcov=1.02; evalue=0; confidence=high |
| Rice | Os02g0699700- identity=70.4; qcov=0.635; evalue=0; confidence=high |
| GO | GO:0000712 (resolution of meiotic recombination intermediates); GO:0000819 (sister chromatid segregation); GO:0003677 (DNA binding); GO:0003918 (DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0006265 (DNA topological change) |
| KEGG | - |
| Pfam | PF00204 (DNA_gyraseB); PF00521 (DNA_topoisoIV); PF01751 (Toprim); PF02518 (HATPase_c); PF16898 (TOPRIM_C) |
| InterPro | - |
| eggNOG | - |
| NR | GeneID:131022308 |
| Rank | 定位位置 | 中文 | Score | Protein ID |
|---|---|---|---|---|
| 1 | Nucleus | 细胞核 | 1.00000 | XP_057807739.1 |
| 2 | Nucleolus | 核仁 | 0.60000 | XP_057807739.1 |
| 3 | Chromosome | 染色体 | 0.40000 | XP_057807739.1 |
| 4 | Centromere | 着丝粒 | 0.00000 | XP_057807739.1 |
| 5 | Chromatin | 染色质 | 0.00000 | XP_057807739.1 |
下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。
| 位置 | REF | ALT | 类型 | 影响 | 携带材料数 | 材料 |
|---|---|---|---|---|---|---|
Chr4:4481426 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | C66 |
Chr4:4481510 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | B44 |
Chr4:4481818 |
TTG |
T |
2bp_deletion | frameshift_variant | 25 | A10,A20,A24,B102,B123,B125,B131,B25,B28,B31,B40,B55,B60,B72,B89,B98,C33,C42,C55,C64,C66,C67,C75,C83,D4 |
Chr4:4481825 |
TG |
T |
1bp_deletion | frameshift_variant | 25 | A10,A20,A24,B102,B123,B125,B131,B25,B28,B31,B40,B55,B60,B72,B89,B98,C33,C42,C55,C64,C66,C67,C75,C83,D4 |
Chr4:4481829 |
T |
TCC |
2bp_insertion | frameshift_variant | 25 | A10,A20,A24,B102,B123,B125,B131,B25,B28,B31,B40,B55,B60,B72,B89,B98,C33,C42,C55,C64,C66,C67,C75,C83,D4 |
Chr4:4481878 |
CA |
C |
1bp_deletion | frameshift_variant | 20 | A4,B114,B118,B130,B132,B140,B19,B78,B98,C1,C19,C31,C4,C45,C46,C53,C56,C59,C74,D2 |
Chr4:4482251 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | D8 |
Chr4:4482306 |
TG |
T |
1bp_deletion | frameshift_variant | 1 | D7 |
Chr4:4482306 |
TG |
T |
1bp_deletion | CDS_variant | 1 | D7 |
Chr4:4482415 |
C |
T |
EMS_canonical_SNV | CDS_variant | 3 | B12,B38,C52 |
Chr4:4482422 |
G |
A |
EMS_canonical_SNV | CDS_variant | 3 | B12,B38,C52 |
Chr4:4482434 |
C |
T |
EMS_canonical_SNV | CDS_variant | 3 | B12,B38,C52 |
结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。
XP_057807739.1PF02518
HATPase_c 82-177 aa
PF00204
DNA_gyraseB 298-431 aa
PF01751
Toprim 460-562 aa
PF16898
TOPRIM_C 578-706 aa
PF00521
DNA_topoisoIV 709-1166 aa
| Protein ID | 来源 | 结构域编号 | 结构域名称 | 类型 | 起始 aa | 终止 aa | E-value | Score | 说明 |
|---|---|---|---|---|---|---|---|---|---|
XP_057807739.1 |
Pfam | PF02518 |
HATPase_c | Domain | 82 | 177 | 2.1e-08 | 35.3 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
XP_057807739.1 |
Pfam | PF00204 |
DNA_gyraseB | Domain | 298 | 431 | 1.1e-23 | 84.3 | DNA gyrase B |
XP_057807739.1 |
Pfam | PF01751 |
Toprim | Family | 460 | 562 | 1.2e-08 | 35.7 | Toprim domain |
XP_057807739.1 |
Pfam | PF16898 |
TOPRIM_C | Family | 578 | 706 | 1.6e-50 | 171.3 | C-terminal associated domain of TOPRIM |
XP_057807739.1 |
Pfam | PF00521 |
DNA_topoisoIV | Domain | 709 | 1166 | 3.5e-116 | 389.3 | DNA gyrase/topoisomerase IV, subunit A |
每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。
1 records
下载 cDNA FASTA1 records
下载 CDS FASTA1 records
下载 Protein FASTAupstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。