Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000558`

染色体: Chr04 坐标: 6229116-6230341 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000558`
名称	SmilChr04G000558
描述	D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	6229116 - 6230341 / `+`

ID 对照

NCBI Gene ID	`LOC131022440`
GeneID	`131022440`
locus_tag	`-`
NCBI Name	`LOC131022440`
原始查询	`LOC131022440`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like
产物	D-3-phosphoglycerate dehydrogenase 3%2C chloroplastic-like
Arabidopsis	`AT3G19480` (AT3G19480) D-3-phosphoglycerate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:821482] identity=85.1; qcov=0.808; evalue=0; confidence=high
Rice	`Os04g0650800` - identity=83.4; qcov=0.808; evalue=0; confidence=high
GO	GO:0004617 (phosphoglycerate dehydrogenase activity); GO:0009570 (chloroplast stroma); GO:0051287 (NAD binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00389 (2-Hacid_dh); PF02826 (2-Hacid_dh_C); PF07991 (KARI_N)
InterPro	-
eggNOG	-
NR	GeneID:131022440

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057807909.1`
2	Cytoplasm	细胞质	0.60000	`XP_057807909.1`
3	Nucleus	细胞核	0.00000	`XP_057807909.1`
4	Chromosome	染色体	0.00000	`XP_057807909.1`
5	Centromere	着丝粒	0.00000	`XP_057807909.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:6229192`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B123,B47,B52,B86
`Chr4:6229210`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B123,B22,B47,B52,B86
`Chr4:6229227`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B137,B140,C4,C48,C83
`Chr4:6229252`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B1,B78
`Chr4:6229270`	`GT`	`G`	1bp_deletion	frameshift_variant	57	A13,A14,A18,A19,A2,A20,A24,A6,B102,B111,B113,B117,B12,B121,B122,B130,B136,B138,B139,B17,B23,B32,B33,B52,B53,B55,B65,B66,B70,B73,B76,B78,B79,B94,B97,C19,C2,C27,C29,C31,C32,C35,C36,C37,C43,C46,C47,C51,C56,C68,C73,C8,C83,C84,C9,D10,D5
`Chr4:6229309`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C41
`Chr4:6229319`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B22
`Chr4:6229324`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B137,C4,C48,C83
`Chr4:6229332`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B137,C4,C48,C83
`Chr4:6229333`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B98
`Chr4:6229360`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B106
`Chr4:6229366`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B119

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807909.1

381 aa

190

381

2-Hacid_dh

2-Hacid_dh_C

KARI_N

PF00389 2-Hacid_dh 7-309 aa PF02826 2-Hacid_dh_C 109-284 aa PF07991 KARI_N 141-244 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807909.1`	Pfam	`PF00389`	2-Hacid_dh	Domain	7	309	4.8e-35	120.9	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
`XP_057807909.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	109	284	3.2e-61	206.5	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057807909.1`	Pfam	`PF07991`	KARI_N	Family	141	244	1e-06	29.1	Acetohydroxy acid isomeroreductase, NADPH-binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057951926.1
CCTCTTCTCTATCTCTCTCCCTCCGCCACCACCGCGACCAGCCCCGCCGCTTCATCGTCCTCTCCATGGACGCGAAGCCGACGATTCTCGTGTCGGAGAAACTGGGAGAGGCCGGGTTGAACCTCCTCAAGGAGTTCGCCAACGTCGATTGCTCGTACAACCTCAGCCCCGAGGAGCTCTGCACCAAGATCTCGCTCTGCGACGCGCTGATTGTGAGGAGCGGGACTAAAGTGAATCGCGAGGTGTTTGAGTCCTCCGCC...

CDS

1 records

下载 CDS FASTA

LOC131022440
ATGGACGCGAAGCCGACGATTCTCGTGTCGGAGAAACTGGGAGAGGCCGGGTTGAACCTCCTCAAGGAGTTCGCCAACGTCGATTGCTCGTACAACCTCAGCCCCGAGGAGCTCTGCACCAAGATCTCGCTCTGCGACGCGCTGATTGTGAGGAGCGGGACTAAAGTGAATCGCGAGGTGTTTGAGTCCTCCGCCGGGAGGCTCAAGGTCGTCGGAAGGGCTGGCGTCGGGATCGATAACGTGGATCTGGCGGCGGCGAC...

Protein

1 records

下载 Protein FASTA

XP_057807909.1
MDAKPTILVSEKLGEAGLNLLKEFANVDCSYNLSPEELCTKISLCDALIVRSGTKVNREVFESSAGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKAGKWERNKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGVELVSFDEAISTADFISLHMPLTAATSKILNDESKGKMKKGVRVINVARGGVIDEEALVRAIDAGIVAQVALDVF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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