Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000829`

染色体: Chr04 坐标: 10448182-10451174 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000829`
名称	SmilChr04G000829
描述	pyruvate decarboxylase 2
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	10448182 - 10451174 / `+`

ID 对照

NCBI Gene ID	`LOC131022669`
GeneID	`131022669`
locus_tag	`-`
NCBI Name	`LOC131022669`
原始查询	`LOC131022669`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate decarboxylase 2
产物	pyruvate decarboxylase 2
Arabidopsis	`AT4G33070` (AT4G33070) Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Source:NCBI gene (formerly Entrezgene);Acc:829444] identity=84.6; qcov=1.01; evalue=0; confidence=high
Rice	`Os03g0293500` (pdc2*) - identity=82.3; qcov=1; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0016831 (carboxy-lyase activity); GO:0030976 (thiamine pyrophosphate binding)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00205 (TPP_enzyme_M); PF02775 (TPP_enzyme_C); PF02776 (TPP_enzyme_N)
InterPro	-
eggNOG	-
NR	GeneID:131022669

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057808169.1`
2	Cytoplasm	细胞质	0.80000	`XP_057808171.1`
3	Nucleus	细胞核	0.00000	`XP_057808169.1`
4	Chromosome	染色体	0.00000	`XP_057808169.1`
5	Centromere	着丝粒	0.00000	`XP_057808169.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:10448731`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A5,B48
`Chr4:10448876`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr4:10449128`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B85,B89
`Chr4:10449588`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B1,B58
`Chr4:10450013`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C43
`Chr4:10450048`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B115,B23
`Chr4:10450145`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr4:10450332`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B66,C79
`Chr4:10450362`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B35,B54
`Chr4:10450847`	`GCT`	`G`	2bp_deletion	frameshift_variant	6	A5,B1,B41,B48,B58,C84
`Chr4:10450852`	`T`	`TAC`	2bp_insertion	frameshift_variant	6	A5,B1,B41,B48,B58,C84
`Chr4:10451061`	`T`	`TC`	1bp_insertion	frameshift_variant	15	A23,B127,B140,B3,B37,B51,B69,B70,B84,C21,C27,C36,C65,D7,D8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808169.1

665 aa

332

665

TPP_enzyme_N

TPP_enzyme_M

TPP_enzyme_C

PF02776 TPP_enzyme_N 44-149 aa PF00205 TPP_enzyme_M 241-359 aa PF02775 TPP_enzyme_C 451-514 aa

XP_057808171.1

605 aa

302

605

TPP_enzyme_N

TPP_enzyme_M

TPP_enzyme_C

PF02776 TPP_enzyme_N 44-149 aa PF00205 TPP_enzyme_M 241-359 aa PF02775 TPP_enzyme_C 451-576 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808169.1`	Pfam	`PF02776`	TPP_enzyme_N	Domain	44	149	2.6e-28	98.9	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
`XP_057808169.1`	Pfam	`PF00205`	TPP_enzyme_M	Domain	241	359	2.4e-22	79.8	Thiamine pyrophosphate enzyme, central domain
`XP_057808169.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	451	514	2.6e-14	54.0	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
`XP_057808171.1`	Pfam	`PF02776`	TPP_enzyme_N	Domain	44	149	2.1e-28	99.2	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
`XP_057808171.1`	Pfam	`PF00205`	TPP_enzyme_M	Domain	241	359	1.9e-22	80.2	Thiamine pyrophosphate enzyme, central domain
`XP_057808171.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	451	576	6.8e-17	62.4	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057952188.1
CGGTCCAGTGGTCCACCGCCTTCTACATTGTTCCCCCATTTTTCAAACCCGAATCCGCCCCCCGTTTCTCTCTCTCTCTCTCTCCCAACTAGTACTATATAATATCTTCGCTCCTTTATTCTCACTCACTAATCACACAAAAATCTCTCAAAATCACAATCCACTTTCCACCCCCTTTTACCCATCAATTCAACAAGTAATTAACTACTGTGAATCACTCTCACAACATGGAAACCAAGGTAGGCTCGCTGGACTCCTGC...

XM_057952186.1
GTTCCCCCATTTTTCAAACCCGAATCCGCCCCCCGTTTCTCTCTCTCTCTCTCTCCCAACTAGTACTATATAATATCTTCGCTCCTTTATTCTCACTCACTAATCACACAAAAATCTCTCAAAATCACAATCCACTTTCCACCCCCTTTTACCCATCAATTCAACAAGTAATTAACTACTGTGAATCACTCTCACAACATGGAAACCAAGGTAGGCTCGCTGGACTCCTGCAGGGCCGCCACGTGTAACGACGTCGGCTG...

CDS

2 records

下载 CDS FASTA

LOC131022669
ATGGAAACCAAGGTAGGCTCGCTGGACTCCTGCAGGGCCGCCACGTGTAACGACGTCGGCTGCCTCCCCTCTAACGGCGCCGTCTCCGCTATCCAGTCCTCCTCCGTGCCGTTCAACTCCGCCGAGGCCACGCTCGGCCGCCACCTCGCCCGCCGCCTCGTGCAGATCGGCGCCAGCGACGTCTTCTCCGTCCCCGGCGACTTCAACCTCACGCTGCTCGACCACCTCATTGCGGAGCCGGGGCTCAACCTGGTCGGCTG...

Protein

2 records

下载 Protein FASTA

XP_057808169.1
METKVGSLDSCRAATCNDVGCLPSNGAVSAIQSSSVPFNSAEATLGRHLARRLVQIGASDVFSVPGDFNLTLLDHLIAEPGLNLVGCCNELNAGYAADGFARARGVGACVVTFTVGGLSVLNAIAGAYSENLPVICIVGGPNSNDYGTNRILHHTIGLPDFTQEMRCFQTVTCYQAVVNNLEDAHELIDTAISTALKESKPVYISVGCNLAAIPHPTFSREPVPFSLSPRLSNKMGLEAAVEAAAEFLNKAVKPVMVGGP...

XP_057808171.1
METKVGSLDSCRAATCNDVGCLPSNGAVSAIQSSSVPFNSAEATLGRHLARRLVQIGASDVFSVPGDFNLTLLDHLIAEPGLNLVGCCNELNAGYAADGFARARGVGACVVTFTVGGLSVLNAIAGAYSENLPVICIVGGPNSNDYGTNRILHHTIGLPDFTQEMRCFQTVTCYQAVVNNLEDAHELIDTAISTALKESKPVYISVGCNLAAIPHPTFSREPVPFSLSPRLSNKMGLEAAVEAAAEFLNKAVKPVMVGGP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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