Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000860`

染色体: Chr04 坐标: 10905330-10911318 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000860`
名称	SmilChr04G000860
描述	ubiquitin-activating enzyme E1 1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	10905330 - 10911318 / `-`

ID 对照

NCBI Gene ID	`LOC131022691`
GeneID	`131022691`
locus_tag	`-`
NCBI Name	`LOC131022691`
原始查询	`LOC131022691`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ubiquitin-activating enzyme E1 1-like
产物	ubiquitin-activating enzyme E1 1-like
Arabidopsis	`AT5G06460` (UBA 2) ubiquitin activating enzyme 2 [Source:NCBI gene (formerly Entrezgene);Acc:830534] identity=77.8; qcov=0.977; evalue=0; confidence=high
Rice	`Os11g0106400` - identity=76.8; qcov=0.978; evalue=0; confidence=high
GO	GO:0004839 (ubiquitin activating enzyme activity); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0006974 (DNA damage response); GO:0016567 (protein ubiquitination)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00899 (ThiF); PF09358 (E1_UFD); PF10585 (UBA_E1_SCCH); PF16190 (E1_FCCH); PF16191 (E1_4HB)
InterPro	-
eggNOG	-
NR	GeneID:131022691

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057808185.1`
2	Cytosol	细胞质基质	1.00000	`XP_057808185.1`
3	Nucleus	细胞核	0.60000	`XP_057808186.1`
4	Chromosome	染色体	0.00000	`XP_057808185.1`
5	Centromere	着丝粒	0.00000	`XP_057808185.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:10905553`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C39,C75
`Chr4:10905558`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr4:10905567`	`G`	`GGC`	2bp_insertion	frameshift_variant	18	A18,A23,B127,B128,B140,B17,B3,B37,B51,B69,B70,B84,C21,C27,C36,C45,D7,D8
`Chr4:10905569`	`CGG`	`C`	2bp_deletion	frameshift_variant	18	A18,A23,B127,B128,B140,B17,B3,B37,B51,B69,B70,B84,C21,C27,C36,C45,D7,D8
`Chr4:10905636`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B17,B64
`Chr4:10905685`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B66,C79
`Chr4:10905700`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:10905798`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C23
`Chr4:10905826`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C23
`Chr4:10905862`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B110,C15,C25
`Chr4:10906050`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:10906670`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C23

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808185.1

1112 aa

556

1112

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

PF00899 ThiF 79-456 aa PF16190 E1_FCCH 253-323 aa PF16191 E1_4HB 324-394 aa PF00899 ThiF 476-1004 aa PF10585 UBA_E1_SCCH 663-744 aa PF10585 UBA_E1_SCCH 759-947 aa PF09358 E1_UFD 1018-1107 aa

XP_057808186.1

1081 aa

540

1081

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

PF00899 ThiF 79-456 aa PF16190 E1_FCCH 253-323 aa PF16191 E1_4HB 324-394 aa PF00899 ThiF 476-973 aa PF10585 UBA_E1_SCCH 663-916 aa PF09358 E1_UFD 987-1076 aa

XP_057808187.1

1066 aa

533

1066

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

PF00899 ThiF 33-410 aa PF16190 E1_FCCH 207-277 aa PF16191 E1_4HB 278-348 aa PF00899 ThiF 430-958 aa PF10585 UBA_E1_SCCH 617-698 aa PF10585 UBA_E1_SCCH 713-901 aa PF09358 E1_UFD 972-1061 aa

XP_057808188.1

1066 aa

533

1066

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

XP_057808189.1

1035 aa

518

1035

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

PF00899 ThiF 33-410 aa PF16190 E1_FCCH 207-277 aa PF16191 E1_4HB 278-348 aa PF00899 ThiF 430-927 aa PF10585 UBA_E1_SCCH 617-870 aa PF09358 E1_UFD 941-1030 aa

XP_057808190.1

1035 aa

518

1035

ThiF

E1_FCCH

E1_4HB

ThiF

UBA_E1_SCCH

E1_UFD

PF00899 ThiF 33-410 aa PF16190 E1_FCCH 207-277 aa PF16191 E1_4HB 278-348 aa PF00899 ThiF 430-927 aa PF10585 UBA_E1_SCCH 617-870 aa PF09358 E1_UFD 941-1030 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808185.1`	Pfam	`PF00899`	ThiF	Domain	79	456	2.7e-87	292.6	ThiF family
`XP_057808185.1`	Pfam	`PF16190`	E1_FCCH	Domain	253	323	4.3e-29	101.1	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808185.1`	Pfam	`PF16191`	E1_4HB	Domain	324	394	4.6e-24	84.9	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808185.1`	Pfam	`PF00899`	ThiF	Domain	476	1004	2.7e-87	292.6	ThiF family
`XP_057808185.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	663	744	7.1e-81	272.5	Ubiquitin-activating enzyme, SCCH domain
`XP_057808185.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	759	947	7.1e-81	272.5	Ubiquitin-activating enzyme, SCCH domain
`XP_057808185.1`	Pfam	`PF09358`	E1_UFD	Domain	1018	1107	2.6e-25	89.6	Ubiquitin fold domain
`XP_057808186.1`	Pfam	`PF00899`	ThiF	Domain	79	456	1.9e-87	293.1	ThiF family
`XP_057808186.1`	Pfam	`PF16190`	E1_FCCH	Domain	253	323	4.1e-29	101.2	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808186.1`	Pfam	`PF16191`	E1_4HB	Domain	324	394	4.4e-24	85.0	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808186.1`	Pfam	`PF00899`	ThiF	Domain	476	973	1.9e-87	293.1	ThiF family
`XP_057808186.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	663	916	1.2e-85	288.1	Ubiquitin-activating enzyme, SCCH domain
`XP_057808186.1`	Pfam	`PF09358`	E1_UFD	Domain	987	1076	2.5e-25	89.6	Ubiquitin fold domain
`XP_057808187.1`	Pfam	`PF00899`	ThiF	Domain	33	410	2.2e-87	292.9	ThiF family
`XP_057808187.1`	Pfam	`PF16190`	E1_FCCH	Domain	207	277	4e-29	101.2	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808187.1`	Pfam	`PF16191`	E1_4HB	Domain	278	348	4.5e-24	85.0	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808187.1`	Pfam	`PF00899`	ThiF	Domain	430	958	2.2e-87	292.9	ThiF family
`XP_057808187.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	617	698	6.4e-81	272.7	Ubiquitin-activating enzyme, SCCH domain
`XP_057808187.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	713	901	6.4e-81	272.7	Ubiquitin-activating enzyme, SCCH domain
`XP_057808187.1`	Pfam	`PF09358`	E1_UFD	Domain	972	1061	2.4e-25	89.7	Ubiquitin fold domain
`XP_057808188.1`	Pfam	`PF00899`	ThiF	Domain	33	410	2.2e-87	292.9	ThiF family
`XP_057808188.1`	Pfam	`PF16190`	E1_FCCH	Domain	207	277	4e-29	101.2	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808188.1`	Pfam	`PF16191`	E1_4HB	Domain	278	348	4.5e-24	85.0	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808188.1`	Pfam	`PF00899`	ThiF	Domain	430	958	2.2e-87	292.9	ThiF family
`XP_057808188.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	617	698	6.4e-81	272.7	Ubiquitin-activating enzyme, SCCH domain
`XP_057808188.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	713	901	6.4e-81	272.7	Ubiquitin-activating enzyme, SCCH domain
`XP_057808188.1`	Pfam	`PF09358`	E1_UFD	Domain	972	1061	2.4e-25	89.7	Ubiquitin fold domain
`XP_057808189.1`	Pfam	`PF00899`	ThiF	Domain	33	410	1.5e-87	293.4	ThiF family
`XP_057808189.1`	Pfam	`PF16190`	E1_FCCH	Domain	207	277	3.8e-29	101.3	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808189.1`	Pfam	`PF16191`	E1_4HB	Domain	278	348	4.2e-24	85.0	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808189.1`	Pfam	`PF00899`	ThiF	Domain	430	927	1.5e-87	293.4	ThiF family
`XP_057808189.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	617	870	1.2e-85	288.2	Ubiquitin-activating enzyme, SCCH domain
`XP_057808189.1`	Pfam	`PF09358`	E1_UFD	Domain	941	1030	2.3e-25	89.8	Ubiquitin fold domain
`XP_057808190.1`	Pfam	`PF00899`	ThiF	Domain	33	410	1.5e-87	293.4	ThiF family
`XP_057808190.1`	Pfam	`PF16190`	E1_FCCH	Domain	207	277	3.8e-29	101.3	Ubiquitin-activating enzyme E1 FCCH domain
`XP_057808190.1`	Pfam	`PF16191`	E1_4HB	Domain	278	348	4.2e-24	85.0	Ubiquitin-activating enzyme E1 four-helix bundle
`XP_057808190.1`	Pfam	`PF00899`	ThiF	Domain	430	927	1.5e-87	293.4	ThiF family
`XP_057808190.1`	Pfam	`PF10585`	UBA_E1_SCCH	Domain	617	870	1.2e-85	288.2	Ubiquitin-activating enzyme, SCCH domain
`XP_057808190.1`	Pfam	`PF09358`	E1_UFD	Domain	941	1030	2.3e-25	89.8	Ubiquitin fold domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

6 records

下载 cDNA FASTA

XM_057952207.1
GTCGATATGTCCGAGTGGTTAAGGAGACAGACTCGAAATCTGTTGGGCTTTGCCTGCGCAGGTTCGAATCCTGCTGTCGACGGAAACTTCCTTTTTTGTTTTGCGCCACCGCCAAACGCCGCCTTACAATACCAAACACCGAGCCTCATTTCTACCCAATTCCCTCTCCTCCAAGCCTAAAATATTTCGCCCCACCCCACATCTGTTCTCCCTTACCCAAACCCCCCTCAAACCCTAATCATCACTTCACACGGAAATAC...

XM_057952205.1
GTCGATATGTCCGAGTGGTTAAGGAGACAGACTCGAAATCTGTTGGGCTTTGCCTGCGCAGGTTCGAATCCTGCTGTCGACGGAAACTTCCTTTTTTGTTTTGCGCCACCGCCAAACGCCGCCTTACAATACCAAACACCGAGCCTCATTTCTACCCAATTCCCTCTCCTCCAAGCCTAAAATATTTCGCCCCACCCCACATCTGTTCTCCCTTACCCAAACCCCCCTCAAACCCTAATCATCACTTCACACGGAAATAC...

CDS

6 records

下载 CDS FASTA

LOC131022691
ATGGTGAATTCAAGCGGTTCACCGGAATTTATGCTTCCTGTGAAGAGAACCACAGCTGGAGCGGAGCTAGGATTGGTTGATTCTTCCGAGCCGACCAAGAAGCACTGCGCCAATTTAGCATCCGACGCCGCCTCGTCTATGGCAGGGGGAAGTAGTCTCAATGGCACTGTTGCCGTGGGCAACGGCAAATTGGCTATTGGCGGCGGCAATGTGTCGGAGATAGATGAGGATCTGCACAGCCGGCAGCTCGCCGTGTACGG...

Protein

6 records

下载 Protein FASTA

XP_057808185.1
MVNSSGSPEFMLPVKRTTAGAELGLVDSSEPTKKHCANLASDAASSMAGGSSLNGTVAVGNGKLAIGGGNVSEIDEDLHSRQLAVYGRETMRRLFASNILISGLQGLGAEIAKNLILAGVKSVSLHDVGTVELWDLSSNFIFSEEDIGKNRALASVTKLQELNNSVMISALTSEMTKEQLADFQAVVFTDISLEKAIEFDDYCHRHQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGKDPHTGIIASISNDNPALVAC...

XP_057808186.1
MVNSSGSPEFMLPVKRTTAGAELGLVDSSEPTKKHCANLASDAASSMAGGSSLNGTVAVGNGKLAIGGGNVSEIDEDLHSRQLAVYGRETMRRLFASNILISGLQGLGAEIAKNLILAGVKSVSLHDVGTVELWDLSSNFIFSEEDIGKNRALASVTKLQELNNSVMISALTSEMTKEQLADFQAVVFTDISLEKAIEFDDYCHRHQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGKDPHTGIIASISNDNPALVAC...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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