Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000020`

染色体: Chr04 坐标: 244269-247576 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000020`
名称	SmilChr04G000020
描述	heat shock cognate protein 80
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	244269 - 247576 / `+`

ID 对照

NCBI Gene ID	`LOC131022831`
GeneID	`131022831`
locus_tag	`-`
NCBI Name	`LOC131022831`
原始查询	`LOC131022831`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	heat shock cognate protein 80
产物	heat shock cognate protein 80
Arabidopsis	`AT5G56000` (Hsp81.4) HEAT SHOCK PROTEIN 81.4 [Source:NCBI gene (formerly Entrezgene);Acc:835698] identity=91.6; qcov=0.999; evalue=0; confidence=high
Rice	`Os09g0482100` (OsHSP82) - identity=89.6; qcov=0.999; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0005829 (cytosol); GO:0005886 (plasma membrane); GO:0006457 (protein folding); GO:0016887 (ATP hydrolysis activity); GO:0032991 (protein-containing complex); GO:0034605 (cellular response to heat); GO:0048471 (perinuclear region of cytoplasm); GO:0050821 (protein stabilization); GO:0051082 (GO:0051082); GO:0140662 (ATP-dependent protein folding chaperone)
KEGG	smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage)); smil04626 (Plant-pathogen interaction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00183 (HSP90); PF02518 (HATPase_c); PF13589 (HATPase_c_3)
InterPro	-
eggNOG	-
NR	GeneID:131022831

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057808341.1`
2	Cytosol	细胞质基质	1.00000	`XP_057808341.1`
3	Nucleus	细胞核	0.40000	`XP_057808341.1`
4	Melanosome	Melanosome	0.40000	`XP_057808341.1`
5	Nucleoplasm	核质	0.20000	`XP_057808341.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:244551`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B76,C12
`Chr4:245459`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B62
`Chr4:245463`	`AAC`	`A`	2bp_deletion	frameshift_variant	220	A1,A10,A11,A13,A14,A15,A16,A18,A19,A2,A20,A21,A22,A23,A25,A3,A4,A5,A6,A7,A8,B1,B10,B101,B102,B103,B106,B107,B108,B11,B110,B111,B112,B113,B114,B115,B117,B118,B12,B120,B121,B122,B123,B124,B126,B128,B129,B13,B131,B132,B133,B134,B135,B136,B137,B138,B14,B15,B16,B17,B18,B19,B2,B21,B23,B24,B25,B26,B27,B28,B3,B30,B31,B33,B34,B36,B37,B38,B39,B4,B40,B41,B42,B43,B44,B45,B46,B47,B48,B49,B5,B51,B52,B53,B55,B56,B57,B59,B6,B60,B61,B62,B63,B64,B65,B66,B67,B68,B69,B71,B73,B74,B75,B76,B77,B78,B80,B81,B82,B83,B84,B85,B86,B87,B88,B89,B9,B90,B91,B92,B94,B95,B96,B97,B99,C1,C10,C11,C12,C14,C15,C16,C17,C18,C2,C20,C21,C22,C23,C24,C25,C26,C27,C28,C29,C3,C31,C33,C34,C35,C36,C37,C38,C39,C4,C40,C42,C44,C45,C46,C47,C48,C49,C5,C50,C51,C52,C54,C55,C56,C57,C58,C59,C6,C60,C61,C62,C63,C64,C66,C67,C68,C69,C7,C70,C71,C72,C73,C74,C75,C76,C78,C8,C80,C82,C84,C85,C87,C9,D1,D10,D11,D2,D3,D4,D5,D6,D7,D8,D9
`Chr4:245472`	`T`	`TGA`	2bp_insertion	stop_gained,frameshift_variant	219	A1,A10,A11,A13,A14,A15,A16,A18,A19,A2,A20,A21,A22,A23,A25,A3,A4,A5,A6,A7,A8,B1,B10,B101,B102,B103,B106,B107,B11,B110,B111,B112,B113,B114,B115,B117,B118,B12,B120,B121,B122,B123,B124,B126,B128,B129,B13,B131,B132,B133,B134,B135,B136,B137,B138,B14,B15,B16,B17,B18,B19,B2,B21,B23,B24,B25,B26,B27,B28,B3,B30,B31,B33,B34,B36,B37,B38,B39,B4,B40,B41,B42,B43,B44,B45,B46,B47,B48,B49,B5,B51,B52,B53,B55,B56,B57,B59,B6,B60,B61,B62,B63,B64,B65,B66,B67,B68,B69,B71,B73,B74,B75,B76,B77,B78,B80,B81,B82,B83,B84,B85,B86,B87,B88,B89,B9,B90,B91,B92,B94,B95,B96,B97,B99,C1,C10,C11,C12,C14,C15,C16,C17,C18,C2,C20,C21,C22,C23,C24,C25,C26,C27,C28,C29,C3,C31,C33,C34,C35,C36,C37,C38,C39,C4,C40,C42,C44,C45,C46,C47,C48,C49,C5,C50,C51,C52,C54,C55,C56,C57,C58,C59,C6,C60,C61,C62,C63,C64,C66,C67,C68,C69,C7,C70,C71,C72,C73,C74,C75,C76,C78,C8,C80,C82,C84,C85,C87,C9,D1,D10,D11,D2,D3,D4,D5,D6,D7,D8,D9
`Chr4:245831`	`GGT`	`G`	2bp_deletion	frameshift_variant	2	B1,B135
`Chr4:245831`	`GGT`	`G`	2bp_deletion	CDS_variant	2	B1,B135
`Chr4:245834`	`C`	`CCA`	2bp_insertion	frameshift_variant	2	B1,B135
`Chr4:245834`	`C`	`CCA`	2bp_insertion	CDS_variant	2	B1,B135
`Chr4:245876`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B2
`Chr4:245879`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B107,B93
`Chr4:245981`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B100,B2,D9
`Chr4:246391`	`TAG`	`T`	2bp_deletion	frameshift_variant	26	A8,B100,B111,B118,B122,B131,B133,B14,B57,B74,B76,B80,B93,B97,C25,C3,C34,C38,C42,C45,C49,C6,C66,C7,C70,C72

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808341.1

701 aa

350

701

HATPase_c

HATPase_c_3

HSP90

PF02518 HATPase_c 31-183 aa PF13589 HATPase_c_3 32-147 aa PF00183 HSP90 186-687 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808341.1`	Pfam	`PF02518`	HATPase_c	Domain	31	183	1.2e-07	32.9	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
`XP_057808341.1`	Pfam	`PF13589`	HATPase_c_3	Domain	32	147	1.2e-08	35.8	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
`XP_057808341.1`	Pfam	`PF00183`	HSP90	Family	186	687	5.6e-239	795.1	Hsp90 protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057952358.1
AAAAGAAAGAGATGGGGAAATCAAACCACGGAAGGATCTAGGATCTCAAAAAAAGAAAAAAAGAAAAATAAAAAAAGCAGAAGGATCTAGAAACCAAGTGGGTATAACTGCTATATAAAATCTCACTCGCTCGTGCTGCCTCATTGCCCTGCCCTCTCTGTTTACGCTCTGTCTCTTCACATTTCTTCAATCACAGTCGATATCTCTGTCACTGAAAATTTTTATTAGAGAGAGAAACCGAGCTTTGGAAATCATGACAA...

CDS

1 records

下载 CDS FASTA

LOC131022831
ATGACAATGGCGGAAACTGAGACGTTTGCCTTCCAGGCCGAGATCAATCAGCTTTTGAGTCTGATCATCAACACTTTCTACAGCAACAAGGAGATCTTTCTACGTGAATTGATCAGCAACTCCTCCGACGCTCTTGACAAGATCCGTTTTGAAAGCTTGACTGACAAAAGCAAGCTAGATGGTCAGCCAGAGCTATTCATCCATATTATTCCTGACAAGACCAATAACACTCTCTCTATCATAGATAGTGGTATTGGTAT...

Protein

1 records

下载 Protein FASTA

XP_057808341.1
MTMAETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIHIIPDKTNNTLSIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVADKVIVTTKHNDDEQYVWESQAGGSFTVTRDTSGEVLGRGTKITLHLKEDQLEYLEERRLKDLIKKHSEFISYPISLWVEKTTEKEISDDEDEEDKKDEEGKVEEVDEEKEKAEKKKKKIKEVSHEW...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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