Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003059`

染色体: Chr04 坐标: 47170546-47174455 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003059`
名称	SmilChr04G003059
描述	mannose-6-phosphate isomerase 2-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	47170546 - 47174455 / `+`

ID 对照

NCBI Gene ID	`LOC131023855`
GeneID	`131023855`
locus_tag	`-`
NCBI Name	`LOC131023855`
原始查询	`LOC131023855`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	mannose-6-phosphate isomerase 2-like
产物	mannose-6-phosphate isomerase 2-like
Arabidopsis	`AT1G67070` (DIN9) Mannose-6-phosphate isomerase, type I [Source:NCBI gene (formerly Entrezgene);Acc:843027] identity=61; qcov=0.978; evalue=6.9e-143; confidence=high
Rice	`Os01g0127900` - identity=60.1; qcov=0.988; evalue=2.25e-135; confidence=high
GO	GO:0004476 (mannose-6-phosphate isomerase activity); GO:0005829 (cytosol); GO:0005975 (carbohydrate metabolic process); GO:0008270 (zinc ion binding); GO:0009298 (GDP-mannose biosynthetic process)
KEGG	smil00051 (Fructose and mannose metabolism - Salvia miltiorrhiza (redroot sage)); smil00520 (Amino sugar and nucleotide sugar metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil01250 (Biosynthesis of nucleotide sugars - Salvia miltiorrhiza (redroot sage))
Pfam	PF01238 (PMI_typeI_C); PF20511 (PMI_typeI_cat); PF20512 (PMI_typeI_hel)
InterPro	-
eggNOG	-
NR	GeneID:131023855

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057809456.1`
2	Cytoplasm	细胞质	0.80000	`XP_057809456.1`
3	Nucleus	细胞核	0.00000	`XP_057809456.1`
4	Chromosome	染色体	0.00000	`XP_057809456.1`
5	Centromere	着丝粒	0.00000	`XP_057809456.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:47170929`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A8
`Chr4:47170938`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A16
`Chr4:47171033`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B119,B40,C22,C50
`Chr4:47171084`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B59

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057809456.1

435 aa

218

435

PMI_typeI_cat

PMI_typeI_hel

PMI_typeI_C

PF20511 PMI_typeI_cat 8-169 aa PF20512 PMI_typeI_hel 201-273 aa PF01238 PMI_typeI_C 351-391 aa

XP_057809457.1

325 aa

162

325

PMI_typeI_cat

PMI_typeI_hel

PMI_typeI_C

PF20511 PMI_typeI_cat 9-59 aa PF20512 PMI_typeI_hel 91-163 aa PF01238 PMI_typeI_C 241-281 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057809456.1`	Pfam	`PF20511`	PMI_typeI_cat	Domain	8	169	9.6e-47	159.4	Phosphomannose isomerase type I, catalytic domain
`XP_057809456.1`	Pfam	`PF20512`	PMI_typeI_hel	Domain	201	273	4.8e-13	50.1	Phosphomannose isomerase type I, helical insertion domain
`XP_057809456.1`	Pfam	`PF01238`	PMI_typeI_C	Domain	351	391	8.2e-06	26.6	Phosphomannose isomerase type I C-terminal
`XP_057809457.1`	Pfam	`PF20511`	PMI_typeI_cat	Domain	9	59	7.2e-21	75.5	Phosphomannose isomerase type I, catalytic domain
`XP_057809457.1`	Pfam	`PF20512`	PMI_typeI_hel	Domain	91	163	2.8e-13	50.9	Phosphomannose isomerase type I, helical insertion domain
`XP_057809457.1`	Pfam	`PF01238`	PMI_typeI_C	Domain	241	281	6.6e-06	26.9	Phosphomannose isomerase type I C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057953473.1
GTAATGTGGACCCAAAAACTGTGAAAACTACTCCCTCACTCTAACTGCCATTTCACAACGACCCCCACCGACGCATAAAGGCCGCCCCCGCCATCATCTCCCTCCCCAAATCCCCTCCGCCGTGGGTCGCGCCGCCGTAATTTCTAATTTTTTACGAACTTTTTTCCTTACAGAAAAAAGTACAGTAAAAATTAGAAAAAATCGAAATTTATTTCCCTCTCATCGTCGCCTTCAAAAAGCCAAACCCTCTGCCCAAATTT...

XM_057953474.1
ACTGCCATTTCACAACGACCCCCACCGACGCATAAAGGCCGCCCCCGCCATCATCTCCCTCCCCAAATCCCCTCCGCCGTGGGTCGCGCCGCCGTAATTTCTAATTTTTTACGAACTTTTTTCCTTACAGAAAAAAGTACAGTAAAAATTAGAAAAAATCGAAATTTATTTCCCTCTCATCGTCGCCTTCAAAAAGCCAAACCCTCTGCCCAAATTTCCTCCATGGGCGTACTGATCTTCCTCTCATTCCCTCTTCTTCT...

CDS

2 records

下载 CDS FASTA

LOC131023855
ATGGGTGCCGAATTTCCGGGAATTGTCAGGCTCAGATGCTCAGTGAAGAGGTACGAATGGGGCAAGGTTGGGGAAGAATCGGGTGTGGCGCGTCTATATGCCAATAATAGTGGGGAGGAGATCGACGGTGATGAGCCGTTCGCCGAATTCTGGATGGGGACCCACGAGTCGGGGCCTTCAACCGTTGTGGCCAACTGCCAAATGCGGAATGGTGGTGTGGAGAGGGAGGGCGGCCTCAAGCGGAATCACTATAATTTAGT...

LOC131023855
ATGGGGTCCCAATCTCCCCTTTCTCTTCAAGTTGCAAAGGCTCTGTCGATACAAGCTCATCCAGATAAGAGTTTAGCTGCAATCCTACATAAGCAACAGCCAGAAGTGTATAAGGATGATAATCACAAGCCTGAGATGGCTTTGGCGCTCACTGAGTTCGAGGCTCTGTGTGGTTTCGTTGGTCTCGAGGAAATTAAAACTGTTCTCCAAAATGTACCTGAGATCTCTGAAGTGGTTGGAACTGCATCGGCAAATCAAGT...

Protein

2 records

下载 Protein FASTA

XP_057809456.1
MGAEFPGIVRLRCSVKRYEWGKVGEESGVARLYANNSGEEIDGDEPFAEFWMGTHESGPSTVVANCQMRNGGVEREGGLKRNHYNLVSLKEWIEKNPSVLGDKVFQKWGPNLPFLFKVLSVAKALSIQAHPDKSLAAILHKQQPEVYKDDNHKPEMALALTEFEALCGFVGLEEIKTVLQNVPEISEVVGTASANQVLHLSKEAGEKKRKEVLQSLFTKLMSASKAVISDAVFKLISRLNIKSKVRGLTEKEELVLRLEK...

XP_057809457.1
MGSQSPLSLQVAKALSIQAHPDKSLAAILHKQQPEVYKDDNHKPEMALALTEFEALCGFVGLEEIKTVLQNVPEISEVVGTASANQVLHLSKEAGEKKRKEVLQSLFTKLMSASKAVISDAVFKLISRLNIKSKVRGLTEKEELVLRLEKQYPGDVGVIASFLFNYVKLNSGEALYLGANEPHAYLHGECVECMATSDNVVRAGLTPKKLDVQTLCSILTYKQGFPEILHGVPSNPYTVKYLPPFDEFEVDQCILPQGAS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器