Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G003470`

染色体: Chr05 坐标: 46094185-46094930 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G003470`
名称	SmilChr05G003470
描述	receptor homology region, transmembrane domain- and RING domain-containing protein 4-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	46094185 - 46094930 / `-`

ID 对照

NCBI Gene ID	`LOC131024561`
GeneID	`131024561`
locus_tag	`-`
NCBI Name	`LOC131024561`
原始查询	`LOC131024561`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	receptor homology region, transmembrane domain- and RING domain-containing protein 4-like
产物	receptor homology region%2C transmembrane domain- and RING domain-containing protein 4-like
Arabidopsis	`AT1G26800` (AT1G26800) RING/U-box superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:839223] identity=44; qcov=0.396; evalue=9.11e-13; confidence=low
Rice	`Os12g0140200` - identity=48.6; qcov=0.33; evalue=1.1e-15; confidence=low
GO	GO:0005737 (cytoplasm); GO:0008270 (zinc ion binding); GO:0016567 (protein ubiquitination); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF17123 (zf-RING_11)
InterPro	-
eggNOG	-
NR	GeneID:131024561

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057810059.1`
2	Cytoplasm	细胞质	0.80000	`XP_057810059.1`
3	Cytosol	细胞质基质	0.20000	`XP_057810059.1`
4	Chromosome	染色体	0.00000	`XP_057810059.1`
5	Centromere	着丝粒	0.00000	`XP_057810059.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:46094277`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B33
`Chr5:46094322`	`C`	`T`	EMS_canonical_SNV	stop_gained	61	A14,A16,A2,A21,A25,A7,A8,B10,B110,B113,B122,B125,B129,B131,B138,B16,B17,B19,B20,B28,B40,B50,B52,B53,B55,B56,B59,B6,B67,B71,B8,B81,B85,B9,B90,B91,B92,C10,C12,C14,C16,C18,C26,C41,C43,C53,C57,C58,C60,C61,C62,C64,C66,C67,C7,C72,C75,C85,C86,D10,D9
`Chr5:46094340`	`GT`	`G`	1bp_deletion	frameshift_variant	18	A24,A6,A8,B110,B19,B22,B40,B52,B60,B63,B9,C10,C26,C41,C75,C86,D10,D9
`Chr5:46094352`	`AT`	`A`	1bp_deletion	frameshift_variant	20	A20,A24,A6,A8,B110,B19,B22,B40,B52,B60,B63,B9,B99,C10,C26,C41,C75,C86,D10,D9
`Chr5:46094356`	`GA`	`G`	1bp_deletion	frameshift_variant	20	A20,A24,A6,A8,B110,B19,B22,B40,B52,B60,B63,B9,B99,C10,C26,C41,C75,C86,D10,D9
`Chr5:46094360`	`A`	`AG`	1bp_insertion	frameshift_variant	20	A20,A24,A6,A8,B110,B19,B22,B40,B52,B60,B63,B9,B99,C10,C26,C41,C75,C86,D10,D9
`Chr5:46094376`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C70
`Chr5:46094634`	`A`	`AT`	1bp_insertion	frameshift_variant	8	A21,B113,B125,B16,B49,C53,C57,C7
`Chr5:46094637`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr5:46094640`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B71
`Chr5:46094661`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B16,B8
`Chr5:46094675`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B8,D7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810059.1

212 aa

106

212

zf-RING_2

zf-RING_11

zf-C3HC4

zf-C3HC4_2

PF13639 zf-RING_2 167-206 aa PF17123 zf-RING_11 168-192 aa PF00097 zf-C3HC4 168-205 aa PF13923 zf-C3HC4_2 168-205 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810059.1`	Pfam	`PF13639`	zf-RING_2	Domain	167	206	3.2e-10	40.8	Ring finger domain
`XP_057810059.1`	Pfam	`PF17123`	zf-RING_11	Domain	168	192	9e-07	29.2	RING-like zinc finger
`XP_057810059.1`	Pfam	`PF00097`	zf-C3HC4	Domain	168	205	2.3e-06	28.1	Zinc finger, C3HC4 type (RING finger)
`XP_057810059.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	168	205	1.1e-06	29.0	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057954076.1
CTTTCTCAAAAAATCCTAAACACAATGAGCATGAATTACGAGAGCGTTAGTTCGACCTCAATGGAAGTAATCGAAAGTGCATTCCGGTCCACCATGTTCCCTCATGTGAAGATCAAATTCCAACTTTCCATACACACCCAAACTTCCAACTATGTTGTAAACCCAGATTCCCCAATGGACCCACACTTTCTTGAATCCCTCCCTACCATCGACTACAACACCGCCGCCCAACTCACCGTTGAAGAATCCTTGTCGCGCGA...

CDS

1 records

下载 CDS FASTA

LOC131024561
ATGAGCATGAATTACGAGAGCGTTAGTTCGACCTCAATGGAAGTAATCGAAAGTGCATTCCGGTCCACCATGTTCCCTCATGTGAAGATCAAATTCCAACTTTCCATACACACCCAAACTTCCAACTATGTTGTAAACCCAGATTCCCCAATGGACCCACACTTTCTTGAATCCCTCCCTACCATCGACTACAACACCGCCGCCCAACTCACCGTTGAAGAATCCTTGTCGCGCGACCATGTACGGGAGGTGCTCGTAGA...

Protein

1 records

下载 Protein FASTA

XP_057810059.1
MSMNYESVSSTSMEVIESAFRSTMFPHVKIKFQLSIHTQTSNYVVNPDSPMDPHFLESLPTIDYNTAAQLTVEESLSRDHVREVLVEAIGDRLPDFERRHLITFAWAEVYKSFTAETLRKYTILSLHFKINIRRRHLYAVETDYPRMVPAADSSFPLLEKCEAEERCCCICLEEVGGGLRMPCSHVFHDGCIIKWLRTSHYCPLCRYQMPVD

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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