Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G003330`

染色体: Chr05 坐标: 43697088-43699154 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G003330`
名称	SmilChr05G003330
描述	6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	43697088 - 43699154 / `+`

ID 对照

NCBI Gene ID	`LOC131024677`
GeneID	`131024677`
locus_tag	`-`
NCBI Name	`LOC131024677`
原始查询	`LOC131024677`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like
产物	6-phosphogluconate dehydrogenase%2C decarboxylating 3%2C chloroplastic-like
Arabidopsis	`AT5G41670` (AT5G41670) 6-phosphogluconate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:834169] identity=83.6; qcov=1; evalue=0; confidence=high
Rice	`Os06g0111500` (Os6PGDH1) - identity=75.4; qcov=0.992; evalue=0; confidence=high
GO	GO:0004616 (phosphogluconate dehydrogenase (decarboxylating) activity); GO:0005829 (cytosol); GO:0006098 (pentose-phosphate shunt); GO:0008114 (phosphogluconate 2-dehydrogenase activity); GO:0009051 (pentose-phosphate shunt, oxidative branch); GO:0046177 (GO:0046177); GO:0050661 (NADP binding)
KEGG	smil00030 (Pentose phosphate pathway - Salvia miltiorrhiza (redroot sage)); smil00480 (Glutathione metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00393 (6PGD); PF03446 (NAD_binding_2)
InterPro	-
eggNOG	-
NR	GeneID:131024677

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057810173.1`
2	Cytoplasm	细胞质	0.80000	`XP_057810173.1`
3	Nucleus	细胞核	0.00000	`XP_057810173.1`
4	Chromosome	染色体	0.00000	`XP_057810173.1`
5	Centromere	着丝粒	0.00000	`XP_057810173.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:43697770`	`C`	`CT`	1bp_insertion	frameshift_variant	9	B103,B109,B65,C15,C18,C53,C58,C63,C78
`Chr5:43697797`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C53,C58
`Chr5:43697984`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B104,B82
`Chr5:43698038`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A11,A3
`Chr5:43698134`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C12,D4
`Chr5:43698166`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr5:43698314`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C82
`Chr5:43698725`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B33,C75
`Chr5:43698780`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C5

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810173.1

488 aa

244

488

NAD_binding_2

6PGD

PF03446 NAD_binding_2 8-179 aa PF00393 6PGD 184-479 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810173.1`	Pfam	`PF03446`	NAD_binding_2	Domain	8	179	1.2e-44	153.0	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057810173.1`	Pfam	`PF00393`	6PGD	Domain	184	479	8.3e-127	423.2	6-phosphogluconate dehydrogenase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057954190.1
CGATTGTGAATTGAAGAAGTTATGAATATTTTAGATGTGAAAGTTTGAATGTAATTGGTGAGTTGGGTGTCCCAATCTAAGATAGTTTAGGAGGCACCAAAAAGAGGGTGAGTCCCACTTAGCAGCAACCCCTAGAAGGAACGACGCCGTTTGGAGGCGCATAGATATAATCGCAGCCCGCAAAAGACAGCCCCTCGTTGCCACCTCAGGTCATCTCACCCTTTCACTCCCTCGACGGGTCCGCCTTATTCAAACCTCTG...

CDS

1 records

下载 CDS FASTA

LOC131024677
ATGGAGTCAGCAACGCTATCACAAATCGGTCTCGCGGGTTTAGCCGTGATGGGGCAGAACCTAGCCCTCAACATCGCCGAGAAAGGCTTCCCGATCTCCGTCTACAATCGCACCACCTCCAAAGTCGACGAAACCCTAGATCGCGCCCACCGCGAGGGCCAGCTGCCCCTCACCGGCCACTACTCGCCCAAGGATTTCGTCCTCTCCCTCCAGAAGCCCCGCTCCGTCATCATCCTCGTCAAGGCCGGGGCGCCCGTCGA...

Protein

1 records

下载 Protein FASTA

XP_057810173.1
MESATLSQIGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETLDRAHREGQLPLTGHYSPKDFVLSLQKPRSVIILVKAGAPVDQTIAALSAYMEPGDTIIDGGNEWYENTERRMVDASTNGLLYLGMGVSGGEDGARNGPSLMPGGSHRAYLNIHNILEKVAAQVDDGPCVTYIGEGGSGNFVKMVHNGIEYGDMQLISEAYDVLKNVGGLGNEELAEIFGEWNRGELESFLIEITSDIFKVEDDESGTGHLVDKI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器