Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G003839`

染色体: Chr05 坐标: 51841199-51845766 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G003839`
名称	SmilChr05G003839
描述	3beta-hydroxysteroid-dehydrogenase/decarboxylase-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	51841199 - 51845766 / `+`

ID 对照

NCBI Gene ID	`LOC131024937`
GeneID	`131024937`
locus_tag	`-`
NCBI Name	`LOC131024937`
原始查询	`LOC131024937`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	3beta-hydroxysteroid-dehydrogenase/decarboxylase-like
产物	3beta-hydroxysteroid-dehydrogenase/decarboxylase-like
Arabidopsis	`AT2G26260` (3BETAHSD/D2) 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 [Source:NCBI gene (formerly Entrezgene);Acc:817166] identity=69.5; qcov=0.99; evalue=0; confidence=high
Rice	`Os03g0405000` - identity=66.4; qcov=0.98; evalue=0; confidence=high
GO	GO:0003854 (3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity); GO:0006694 (steroid biosynthetic process)
KEGG	smil00100 (Steroid biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF02719 (Polysacc_synt_2); PF04321 (RmlD_sub_bind); PF05368 (NmrA); PF07993 (NAD_binding_4); PF13460 (NAD_binding_10); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131024937

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057810484.1`
2	Endoplasmic reticulum membrane	内质网膜	0.40000	`XP_057810484.1`
3	Nucleus	细胞核	0.00000	`XP_057810484.1`
4	Chromosome	染色体	0.00000	`XP_057810484.1`
5	Centromere	着丝粒	0.00000	`XP_057810484.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:51841331`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A15
`Chr5:51841377`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B28
`Chr5:51842124`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B16
`Chr5:51843080`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C9
`Chr5:51843400`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C72
`Chr5:51843410`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A6,B105,B15
`Chr5:51843501`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C72
`Chr5:51843507`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A23,B104,B107,B93,D11
`Chr5:51843536`	`CA`	`C`	1bp_deletion	frameshift_variant	5	A23,B104,B107,B93,D11
`Chr5:51843536`	`CA`	`C`	1bp_deletion	CDS_variant	5	A23,B104,B107,B93,D11
`Chr5:51843990`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C36
`Chr5:51844001`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B101,B49,C2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810484.1

410 aa

205

410

Polysacc_synt_2

NmrA

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

NAD_binding_10

PF02719 Polysacc_synt_2 9-129 aa PF05368 NmrA 9-129 aa PF01370 Epimerase 9-239 aa PF01073 3Beta_HSD 9-284 aa PF16363 GDP_Man_Dehyd 10-349 aa PF07993 NAD_binding_4 11-229 aa PF04321 RmlD_sub_bind 43-282 aa PF13460 NAD_binding_10 56-133 aa

XP_057810485.1

410 aa

205

410

Polysacc_synt_2

NmrA

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

NAD_binding_10

XP_057810486.1

410 aa

205

410

Polysacc_synt_2

NmrA

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

NAD_binding_10

XP_057810487.1

410 aa

205

410

Polysacc_synt_2

NmrA

Epimerase

3Beta_HSD

GDP_Man_Dehyd

NAD_binding_4

RmlD_sub_bind

NAD_binding_10

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810484.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	2.7e-09	37.4	Polysaccharide biosynthesis protein
`XP_057810484.1`	Pfam	`PF05368`	NmrA	Family	9	129	3.7e-07	30.7	NmrA-like family
`XP_057810484.1`	Pfam	`PF01370`	Epimerase	Family	9	239	1.8e-38	133.0	NAD dependent epimerase/dehydratase family
`XP_057810484.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	284	1.3e-78	264.6	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057810484.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	349	3.3e-21	76.8	GDP-mannose 4,6 dehydratase
`XP_057810484.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.2e-13	50.2	Male sterility protein
`XP_057810484.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	43	282	5.4e-13	49.4	RmlD substrate binding domain
`XP_057810484.1`	Pfam	`PF13460`	NAD_binding_10	Domain	56	133	7.4e-10	39.7	NAD(P)H-binding
`XP_057810485.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	2.7e-09	37.4	Polysaccharide biosynthesis protein
`XP_057810485.1`	Pfam	`PF05368`	NmrA	Family	9	129	3.7e-07	30.7	NmrA-like family
`XP_057810485.1`	Pfam	`PF01370`	Epimerase	Family	9	239	1.8e-38	133.0	NAD dependent epimerase/dehydratase family
`XP_057810485.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	284	1.3e-78	264.6	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057810485.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	349	3.3e-21	76.8	GDP-mannose 4,6 dehydratase
`XP_057810485.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.2e-13	50.2	Male sterility protein
`XP_057810485.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	43	282	5.4e-13	49.4	RmlD substrate binding domain
`XP_057810485.1`	Pfam	`PF13460`	NAD_binding_10	Domain	56	133	7.4e-10	39.7	NAD(P)H-binding
`XP_057810486.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	2.7e-09	37.4	Polysaccharide biosynthesis protein
`XP_057810486.1`	Pfam	`PF05368`	NmrA	Family	9	129	3.7e-07	30.7	NmrA-like family
`XP_057810486.1`	Pfam	`PF01370`	Epimerase	Family	9	239	1.8e-38	133.0	NAD dependent epimerase/dehydratase family
`XP_057810486.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	284	1.3e-78	264.6	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057810486.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	349	3.3e-21	76.8	GDP-mannose 4,6 dehydratase
`XP_057810486.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.2e-13	50.2	Male sterility protein
`XP_057810486.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	43	282	5.4e-13	49.4	RmlD substrate binding domain
`XP_057810486.1`	Pfam	`PF13460`	NAD_binding_10	Domain	56	133	7.4e-10	39.7	NAD(P)H-binding
`XP_057810487.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	9	129	2.7e-09	37.4	Polysaccharide biosynthesis protein
`XP_057810487.1`	Pfam	`PF05368`	NmrA	Family	9	129	3.7e-07	30.7	NmrA-like family
`XP_057810487.1`	Pfam	`PF01370`	Epimerase	Family	9	239	1.8e-38	133.0	NAD dependent epimerase/dehydratase family
`XP_057810487.1`	Pfam	`PF01073`	3Beta_HSD	Family	9	284	1.3e-78	264.6	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057810487.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	10	349	3.3e-21	76.8	GDP-mannose 4,6 dehydratase
`XP_057810487.1`	Pfam	`PF07993`	NAD_binding_4	Family	11	229	3.2e-13	50.2	Male sterility protein
`XP_057810487.1`	Pfam	`PF04321`	RmlD_sub_bind	Domain	43	282	5.4e-13	49.4	RmlD substrate binding domain
`XP_057810487.1`	Pfam	`PF13460`	NAD_binding_10	Domain	56	133	7.4e-10	39.7	NAD(P)H-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057954503.1
CGCATGCCACAGAAGAATCCTAACAGAATCTATTCCAACTCACATCTTCTGTTTCAGTATTCCATCACTGGTGACAAACGATGGTCGCCGGAGAGAGGTGGTGCGTGGTGACGGGCGGGAGAGGCTTCGCGGCGAGGCATCTGGTGGTTATGCTCATCCAACGCGGCGTTTATTCCGTGCGCATTTCCGATTTGGGGCCTACCATCGCGCTCGACGCCGACGAGGAGACCGGCGTTCTCGGCAGCGCATTCAAGTCCGGT...

XM_057954504.1
CGCATGCCACAGAAGAATCCTAACAGAATCTATTCCAACTCACATCTTCTGTTTCAGTATTCCATCACTGGTGACAAACGATGGTCGCCGGAGAGAGGTGGTGCGTGGTGACGGGCGGGAGAGGCTTCGCGGCGAGGCATCTGGTGGTTATGCTCATCCAACGCGGCGTTTATTCCGTGCGCATTTCCGATTTGGGGCCTACCATCGCGCTCGACGCCGACGAGGAGACCGGCGTTCTCGGCAGCGCATTCAAGTCCGGT...

CDS

4 records

下载 CDS FASTA

LOC131024937
ATGGTCGCCGGAGAGAGGTGGTGCGTGGTGACGGGCGGGAGAGGCTTCGCGGCGAGGCATCTGGTGGTTATGCTCATCCAACGCGGCGTTTATTCCGTGCGCATTTCCGATTTGGGGCCTACCATCGCGCTCGACGCCGACGAGGAGACCGGCGTTCTCGGCAGCGCATTCAAGTCCGGTCGCGCGCAGTATGTCACCGCAGATCTTCGCGACAAATCTCAAGTGCTCAGAGCTTTCAATGGAGCTGAAGTCGTGTTTCA...

Protein

4 records

下载 Protein FASTA

XP_057810484.1
MVAGERWCVVTGGRGFAARHLVVMLIQRGVYSVRISDLGPTIALDADEETGVLGSAFKSGRAQYVTADLRDKSQVLRAFNGAEVVFHMAAPDSSINNHQLQYSVNVQGTKNVIDACIEQKVKRLIYTSSPSVVFDGVHEIINGDESLPYPSTHNDSYSATKAEGEALVLKSNGSNGLLTCCIRPSSIFGPGDKLLVPSLIAAARAGKSKFIIGDGNNIYDFTYVENVAHAHICAEQALASEKSIAEKAGGQAYFITNMER...

XP_057810485.1
MVAGERWCVVTGGRGFAARHLVVMLIQRGVYSVRISDLGPTIALDADEETGVLGSAFKSGRAQYVTADLRDKSQVLRAFNGAEVVFHMAAPDSSINNHQLQYSVNVQGTKNVIDACIEQKVKRLIYTSSPSVVFDGVHEIINGDESLPYPSTHNDSYSATKAEGEALVLKSNGSNGLLTCCIRPSSIFGPGDKLLVPSLIAAARAGKSKFIIGDGNNIYDFTYVENVAHAHICAEQALASEKSIAEKAGGQAYFITNMER...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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