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中文 EN

Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。
示例

当前解析结果

SmilChr05G004379

染色体: Chr05 坐标: 57303683-57309397 链方向: + 类型: protein_coding

基本信息

统一新 Gene IDSmilChr05G004379
名称SmilChr05G004379
描述histidine kinase 3
染色体 / SeqIDChr05 / NC_080391.1
坐标与链方向57303683 - 57309397 / +

ID 对照

NCBI Gene IDLOC131025428
GeneID131025428
locus_tag-
NCBI NameLOC131025428
原始查询LOC131025428

查看完整 ID 对照表

功能注释

来源GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述histidine kinase 3
产物histidine kinase 3
ArabidopsisAT1G27320 (HK3)
histidine kinase 3 [Source:NCBI gene (formerly Entrezgene);Acc:839621]
identity=63.9; qcov=1.02; evalue=0; confidence=high
RiceOs01g0923700 (HK3)
-
identity=61.1; qcov=0.938; evalue=0; confidence=high
GOGO:0000155 (phosphorelay sensor kinase activity); GO:0000160 (phosphorelay signal transduction system); GO:0016310 (phosphorylation)
KEGGsmil04075 (Plant hormone signal transduction - Salvia miltiorrhiza (redroot sage))
PfamPF00072 (Response_reg); PF00512 (HisKA); PF02518 (HATPase_c); PF03924 (CHASE); PF24896 (Receiver_CRE1)
InterPro-
eggNOG-
NRGeneID:131025428

打开注释模块

亚细胞定位 Top 5

Rank定位位置中文ScoreProtein ID
1 Endoplasmic reticulum 内质网 1.00000 XP_057811181.1
2 Endoplasmic reticulum membrane 内质网膜 0.80000 XP_057811181.1
3 Nucleus 细胞核 0.00000 XP_057811181.1
4 Chromosome 染色体 0.00000 XP_057811181.1
5 Centromere 着丝粒 0.00000 XP_057811181.1

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置 REF ALT 类型 影响 携带材料数 材料
Chr5:57304735 TG T 1bp_deletion frameshift_variant 1 B18
Chr5:57304735 TG T 1bp_deletion CDS_variant 1 B18
Chr5:57304778 G A EMS_canonical_SNV CDS_variant 1 B138
Chr5:57305615 C T EMS_canonical_SNV CDS_variant 1 B67
Chr5:57305925 G A EMS_canonical_SNV CDS_variant 1 D9
Chr5:57307191 G A EMS_canonical_SNV CDS_variant 1 B36
Chr5:57307797 C T EMS_canonical_SNV CDS_variant 1 B114
Chr5:57307932 C T EMS_canonical_SNV CDS_variant 1 C60
Chr5:57308206 G A EMS_canonical_SNV CDS_variant 5 A2,B101,B138,B80,C61
Chr5:57308364 C T EMS_canonical_SNV CDS_variant 4 A1,B26,B76,C77
Chr5:57308373 C T EMS_canonical_SNV CDS_variant 1 C51
Chr5:57308564 G A EMS_canonical_SNV CDS_variant 1 C38

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057811181.1
1027 aa
N
1
514
1027
CHASE
HisKA
HATPase_c
Receiver_CRE1
Response_reg
C
PF03924 CHASE 159-355 aa PF00512 HisKA 443-508 aa PF02518 HATPase_c 630-707 aa PF24896 Receiver_CRE1 732-856 aa PF00072 Response_reg 883-953 aa
XP_057811183.1
1027 aa
N
1
514
1027
CHASE
HisKA
HATPase_c
Receiver_CRE1
Response_reg
C
PF03924 CHASE 159-355 aa PF00512 HisKA 443-508 aa PF02518 HATPase_c 630-707 aa PF24896 Receiver_CRE1 732-856 aa PF00072 Response_reg 883-953 aa
XP_057811184.1
1009 aa
N
1
504
1009
CHASE
HisKA
HATPase_c
Receiver_CRE1
Response_reg
C
PF03924 CHASE 141-337 aa PF00512 HisKA 425-490 aa PF02518 HATPase_c 612-689 aa PF24896 Receiver_CRE1 714-838 aa PF00072 Response_reg 865-935 aa
Protein ID 来源 结构域编号 结构域名称 类型 起始 aa 终止 aa E-value Score 说明
XP_057811181.1 Pfam PF03924 CHASE Domain 159 355 1.6e-37 129.8 CHASE domain
XP_057811181.1 Pfam PF00512 HisKA Domain 443 508 3.8e-22 78.8 His Kinase A (phospho-acceptor) domain
XP_057811181.1 Pfam PF02518 HATPase_c Domain 630 707 4.9e-23 82.4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
XP_057811181.1 Pfam PF24896 Receiver_CRE1 Domain 732 856 1.8e-40 139.0 AHK4/CRE1/WOL first receiver domain
XP_057811181.1 Pfam PF00072 Response_reg Domain 883 953 1.2e-20 74.4 Response regulator receiver domain
XP_057811183.1 Pfam PF03924 CHASE Domain 159 355 1.6e-37 129.8 CHASE domain
XP_057811183.1 Pfam PF00512 HisKA Domain 443 508 3.8e-22 78.8 His Kinase A (phospho-acceptor) domain
XP_057811183.1 Pfam PF02518 HATPase_c Domain 630 707 4.9e-23 82.4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
XP_057811183.1 Pfam PF24896 Receiver_CRE1 Domain 732 856 1.8e-40 139.0 AHK4/CRE1/WOL first receiver domain
XP_057811183.1 Pfam PF00072 Response_reg Domain 883 953 1.2e-20 74.4 Response regulator receiver domain
XP_057811184.1 Pfam PF03924 CHASE Domain 141 337 1.6e-37 129.9 CHASE domain
XP_057811184.1 Pfam PF00512 HisKA Domain 425 490 3.7e-22 78.8 His Kinase A (phospho-acceptor) domain
XP_057811184.1 Pfam PF02518 HATPase_c Domain 612 689 4.7e-23 82.5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
XP_057811184.1 Pfam PF24896 Receiver_CRE1 Domain 714 838 1.7e-40 139.1 AHK4/CRE1/WOL first receiver domain
XP_057811184.1 Pfam PF00072 Response_reg Domain 865 935 1.1e-20 74.5 Response regulator receiver domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

6 records

下载 cDNA FASTA
XR_009102170.1
TCCTTTACTAGCAGACATTTCTACCACCATATTCCCCTCATCTTACTTTCACAGATTCTTGTTGCATAGTGTCCATATTAATCTAAGCTTTTCTCTTTTCTTTTTTCTCCCCCTCTTTCCCTCTTAGATGCTTTTGCTCTCTTTCTTTTTTTTTCTTTTTTATTTTTTATTTTCTCGTAGTGGGAACATTATTTACTGCAGCAATCATTAATCTTTCAAACATATTATTACCTCAGTTGCTGTCCAGAGCTCCAAATAGT...
XR_009102171.1
CTAGCAGACATTTCTACCACCATATTCCCCTCATCTTACTTTCACAGATTCTTGTTGCATAGTGTCCATATTAATCTAAGCTTTTCTCTTTTCTTTTTTCTCCCCCTCTTTCCCTCTTAGATGCTTTTGCTCTCTTTCTTTTTTTTTCTTTTTTATTTTTTATTTTCTCGTAGTGGGAACATTATTTACTGCAGCAATCATTAATCTTTCAAACATATTATTACCTCAGTTGCTGTCCAGAGCTCCAAATAGTTGGCTCA...

CDS

3 records

下载 CDS FASTA
LOC131025428
ATGAACTTACTTCACGTAGTTGGATTTGGGTTGAAGGTGGGCCATCTTCTTTTGATGCTTTGCTGCTGGTTTCTGTCTCTGATCTCTTTGAATTGGCTGAGTAATGGAAAAATCATGACCACCAAGAATAGTTTGCTTGGTGATGGAGGGAAGATATGGATGAAACTGTGGGATCAGCTACCGGGCTGTGGTTCGAAGATCCATCACCAGTATTCACAGTATATATCCTTGAGGAGAGTGAGGAAGAATTGGTGGACCAA...
LOC131025428
ATGAACTTACTTCACGTAGTTGGATTTGGGTTGAAGGTGGGCCATCTTCTTTTGATGCTTTGCTGCTGGTTTCTGTCTCTGATCTCTTTGAATTGGCTGAGTAATGGAAAAATCATGACCACCAAGAATAGTTTGCTTGGTGATGGAGGGAAGATATGGATGAAACTGTGGGATCAGCTACCGGGCTGTGGTTCGAAGATCCATCACCAGTATTCACAGTATATATCCTTGAGGAGAGTGAGGAAGAATTGGTGGACCAA...

Protein

3 records

下载 Protein FASTA
XP_057811181.1
MNLLHVVGFGLKVGHLLLMLCCWFLSLISLNWLSNGKIMTTKNSLLGDGGKIWMKLWDQLPGCGSKIHHQYSQYISLRRVRKNWWTKLLITWIVFGIITSLSVFWYMRSQAIEKRKETLASMCDERARMLQDQFNVSMNHIQAMSVIISIFHHDKNPSAIDQRTFARYTEKTSFERPLTSGVAYAVRVLDAEREQFEIQQGWTIKRMDKDEQTPVHEDEYDPEDLEPSPVQEEYAPVIFAQETVAHVISVDMLSGKEDRD...
XP_057811183.1
MNLLHVVGFGLKVGHLLLMLCCWFLSLISLNWLSNGKIMTTKNSLLGDGGKIWMKLWDQLPGCGSKIHHQYSQYISLRRVRKNWWTKLLITWIVFGIITSLSVFWYMRSQAIEKRKETLASMCDERARMLQDQFNVSMNHIQAMSVIISIFHHDKNPSAIDQRTFARYTEKTSFERPLTSGVAYAVRVLDAEREQFEIQQGWTIKRMDKDEQTPVHEDEYDPEDLEPSPVQEEYAPVIFAQETVAHVISVDMLSGKEDRD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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