Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G002549`

染色体: Chr01 坐标: 43593591-43603703 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G002549`
名称	SmilChr01G002549
描述	glyoxylate/hydroxypyruvate reductase HPR3
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	43593591 - 43603703 / `+`

ID 对照

NCBI Gene ID	`LOC131026344`
GeneID	`131026344`
locus_tag	`-`
NCBI Name	`LOC131026344`
原始查询	`LOC131026344`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	glyoxylate/hydroxypyruvate reductase HPR3
产物	glyoxylate/hydroxypyruvate reductase HPR3
Arabidopsis	`AT1G12550` (HPR3) D-isomer specific 2-hydroxyacid dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:837811] identity=54.4; qcov=0.952; evalue=5.74e-118; confidence=high
Rice	`Os04g0107200` - identity=56.1; qcov=0.789; evalue=2.76e-101; confidence=high
GO	GO:0005829 (cytosol); GO:0016618 (hydroxypyruvate reductase [NAD(P)H] activity); GO:0030267 (glyoxylate reductase (NADPH) activity); GO:0051287 (NAD binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00389 (2-Hacid_dh); PF02826 (2-Hacid_dh_C)
InterPro	-
eggNOG	-
NR	GeneID:131026344

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057812185.1`
2	Cytoplasm	细胞质	0.80000	`XP_057812185.1`
3	Peroxisome	过氧化物酶体	0.20000	`XP_057812185.1`
4	Nucleus	细胞核	0.00000	`XP_057812185.1`
5	Chromosome	染色体	0.00000	`XP_057812185.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:43593902`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A14,C83
`Chr1:43594020`	`TGC`	`T`	2bp_deletion	frameshift_variant	1	B60
`Chr1:43594020`	`TGC`	`T`	2bp_deletion	CDS_variant	1	B60
`Chr1:43594097`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C77
`Chr1:43594291`	`CA`	`C`	1bp_deletion	frameshift_variant	1	B130
`Chr1:43594291`	`CA`	`C`	1bp_deletion	CDS_variant	1	B130
`Chr1:43600731`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	D4,D5
`Chr1:43600749`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B138,B51,C22,C3
`Chr1:43600776`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C2,C77
`Chr1:43600783`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B102,B109
`Chr1:43600804`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:43600822`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A20,B72,C33,C41,C46

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057812185.1

332 aa

166

332

2-Hacid_dh

2-Hacid_dh_C

PF00389 2-Hacid_dh 56-325 aa PF02826 2-Hacid_dh_C 124-296 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057812185.1`	Pfam	`PF00389`	2-Hacid_dh	Domain	56	325	8.2e-15	55.4	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
`XP_057812185.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	124	296	3.3e-51	173.9	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009102250.1
GTATCCAAACCCATAGAAAATGTCGACTGCTGAATTAATAATCCATTACAAGTTTTGTGTGTATCCAAAATGTGAACTGACATGAGAATAAAAAAACATTGAAGATTCTGCCCAGAAAGGAAAAGACAAGATCAGCAAGTAGTTTTTTTTTCTTCCACCAATTAGGTAATCAGCCTTAAATCATAAATAATATTTTTGCTCACGAAACGCAATGCTATTCCCACGATCTTCTGCAACATGGCCGCCGCCGACGACGACGA...

XM_057956202.1
GTATCCAAACCCATAGAAAATGTCGACTGCTGAATTAATAATCCATTACAAGTTTTGTGTGTATCCAAAATGTGAACTGACATGAGAATAAAAAAACATTGAAGATTCTGCCCAGAAAGGAAAAGACAAGATCAGCAAGTAGTTTTTTTTTCTTCCACCAATTAGGTAATCAGCCTTAAATCATAAATAATATTTTTGCTCACGAAACGCAATGCTATTCCCACGATCTTCTGCAACATGGCCGCCGCCGACGACGACGA...

CDS

1 records

下载 CDS FASTA

LOC131026344
ATGGCCGCCGCCGACGACGACGAAGGCCACCAGCCCAAAGGAACGCCGCCACTGCTTATTCTCCACCACCTCCCGAATTTCAAGCTACCGATTTTCCCTCTCCTCCGCGCCAGATACACCGTCCTCGACCCGAGCGACGAACCACCCGACCCGTCATTCCCGACCCTCTCGAAGGCCGCGCGCCTCATGCTGTGCGCGGGGCCCACGCCCGTCACGGCCGACGACCTCGACAGGTACCCCGCCCTCGAGTGCGTGATCGG...

Protein

1 records

下载 Protein FASTA

XP_057812185.1
MAAADDDEGHQPKGTPPLLILHHLPNFKLPIFPLLRARYTVLDPSDEPPDPSFPTLSKAARLMLCAGPTPVTADDLDRYPALECVIGSSAGVNHFDLAACRRRGVRLTTAGDSFSDDVADYAVGLAIDVLRRVSAADRFVRAGSWPVRKEYGLGAKVSGKRVGIVGLGSIGSRVAKRFEAFGCSIAYTSTKMKPNVSYSYYADVAHLASNADILIVCSALTDETRHLINKDVMSALGKSGIIVNVGRGALVDEKCLVEMV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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