Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G000470`

染色体: Chr01 坐标: 9592626-9605359 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G000470`
名称	SmilChr01G000470
描述	E3 ubiquitin-protein ligase listerin
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	9592626 - 9605359 / `+`

ID 对照

NCBI Gene ID	`LOC131006531`
GeneID	`131006531`
locus_tag	`-`
NCBI Name	`LOC131006531`
原始查询	`SmilChr01G000470`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase listerin
产物	E3 ubiquitin-protein ligase listerin
Arabidopsis	`AT5G58410` (AT5G58410) HEAT/U-box domain-containing protein [Source:NCBI gene (formerly Entrezgene);Acc:835954] identity=47.6; qcov=1.03; evalue=0; confidence=high
Rice	`Os01g0977600` (P0020E09.22-1) - identity=42.2; qcov=1.05; evalue=0; confidence=medium
GO	GO:0005829 (cytosol); GO:0008270 (zinc ion binding); GO:0043023 (ribosomal large subunit binding); GO:0061630 (ubiquitin protein ligase activity); GO:0072344 (rescue of stalled cytosolic ribosome); GO:1990112 (RQC complex); GO:1990116 (ribosome-associated ubiquitin-dependent protein catabolic process)
KEGG	-
Pfam	PF13639 (zf-RING_2); PF22958 (Ltn1_1st); PF22999 (LTN1_E3_ligase_6th); PF23009 (UBC_like)
InterPro	-
eggNOG	-
NR	GeneID:131006531

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057789666.1`
2	Nucleus membrane	核膜	0.40000	`XP_057789666.1`
3	Cytoplasm	细胞质	0.20000	`XP_057789666.1`
4	Chromosome	染色体	0.00000	`XP_057789666.1`
5	Centromere	着丝粒	0.00000	`XP_057789666.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:9592996`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B126,D2
`Chr1:9593742`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A8,B19,B27,C56,C60
`Chr1:9593965`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D6
`Chr1:9595307`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B109,B120,B140,C24,C25
`Chr1:9595389`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B103
`Chr1:9596725`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	C49
`Chr1:9596725`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C49
`Chr1:9597474`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B71
`Chr1:9598738`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B71,C49
`Chr1:9598839`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A16,B29,C42
`Chr1:9598914`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C32,C68
`Chr1:9599755`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057789666.1

1864 aa

932

1864

Ltn1_1st

LTN1_E3_ligase_6th

UBC_like

zf-RING_2

PF22958 Ltn1_1st 59-383 aa PF22999 LTN1_E3_ligase_6th 1473-1714 aa PF23009 UBC_like 1724-1807 aa PF13639 zf-RING_2 1813-1861 aa

XP_057789667.1

1864 aa

932

1864

Ltn1_1st

LTN1_E3_ligase_6th

UBC_like

zf-RING_2

PF22958 Ltn1_1st 59-383 aa PF22999 LTN1_E3_ligase_6th 1473-1714 aa PF23009 UBC_like 1724-1807 aa PF13639 zf-RING_2 1813-1861 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057789666.1`	Pfam	`PF22958`	Ltn1_1st	Repeat	59	383	9.3e-91	305.3	E3 ubiquitin-protein ligase listerin, N-terminal domain
`XP_057789666.1`	Pfam	`PF22999`	LTN1_E3_ligase_6th	Repeat	1473	1714	9.5e-33	114.3	LTN1 family HEAT repeat region
`XP_057789666.1`	Pfam	`PF23009`	UBC_like	Domain	1724	1807	2.4e-28	98.6	Ubiquitin conjugating domain-like
`XP_057789666.1`	Pfam	`PF13639`	zf-RING_2	Domain	1813	1861	4.6e-07	30.7	Ring finger domain
`XP_057789667.1`	Pfam	`PF22958`	Ltn1_1st	Repeat	59	383	9.3e-91	305.3	E3 ubiquitin-protein ligase listerin, N-terminal domain
`XP_057789667.1`	Pfam	`PF22999`	LTN1_E3_ligase_6th	Repeat	1473	1714	9.5e-33	114.3	LTN1 family HEAT repeat region
`XP_057789667.1`	Pfam	`PF23009`	UBC_like	Domain	1724	1807	2.4e-28	98.6	Ubiquitin conjugating domain-like
`XP_057789667.1`	Pfam	`PF13639`	zf-RING_2	Domain	1813	1861	4.6e-07	30.7	Ring finger domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057933683.1
TCCTTTTGGAACAGCCCCCTCTTCTCTCTCCTCTCTTCTCCCTCCTTCAGCCAAAACCCAAAACCTCCATTAACAGAGCAGCTGATTTCAGCTCAAATTGAATCGTTGTTAGAAAAATCTTAGCTTTTCAGCTGATTCAATTCGAGTTGCAGAGAATGGGGAGAGCGAAGGGAGATGCTGCAAGAACCAAGTCTCGCCCCTCCAGCAGCAGCATGGCTGCTTCGCTGTTGCCGTCGGGCGCCACAGCGGTGGGGTTCGGA...

XM_057933684.1
TCCTTTTGGAACAGCCCCCTCTTCTCTCTCCTCTCTTCTCCCTCCTTCAGCCAAAACCCAAAACCTCCATTAACAGAGCAGCTGATTTCAGCTCAAATTGAATCGTTGTTAGAAAAATCTTAGCTTTTCAGCTGATTCAATTCGAGTTGCAGAGAATGGGGAGAGCGAAGGGAGATGCTGCAAGAACCAAGTCTCGCCCCTCCAGCAGCAGCATGGCTGCTTCGCTGTTGCCGTCGGGCGCCACAGCGGTGGGGTTCGGA...

CDS

2 records

下载 CDS FASTA

LOC131006531
ATGGGGAGAGCGAAGGGAGATGCTGCAAGAACCAAGTCTCGCCCCTCCAGCAGCAGCATGGCTGCTTCGCTGTTGCCGTCGGGCGCCACAGCGGTGGGGTTCGGAGGCTATGTCGGGAGTTCGCGGGTGGATTCATCAATTGCATCGACGCCTGATGCCACTCCTGTGTCGGATATTGATGGCGACCTGGCGCTGCACTTGAAGCGGCTTTCGCGCAAAGATCCCACCACTAAGCTTAAAGCGTTGACCTCACTTTCTCA...

Protein

2 records

下载 Protein FASTA

XP_057789666.1
MGRAKGDAARTKSRPSSSSMAASLLPSGATAVGFGGYVGSSRVDSSIASTPDATPVSDIDGDLALHLKRLSRKDPTTKLKALTSLSQLMEEKSTKELIIIIPQWAFEYKKLLLDYNREVRRATHDTMTNLVTVVGRDLAPHLKPLIGPWWFSQFDSIYEVSQAAKRSFQTAFPSQEKRVDALMFYSTEIFTYIEENLKLTPQSLSDKATASDELEEMHQQVLSSSLLAVTALYDIFFARSGSEYVTGESKYGVKARSIAL...

XP_057789667.1
MGRAKGDAARTKSRPSSSSMAASLLPSGATAVGFGGYVGSSRVDSSIASTPDATPVSDIDGDLALHLKRLSRKDPTTKLKALTSLSQLMEEKSTKELIIIIPQWAFEYKKLLLDYNREVRRATHDTMTNLVTVVGRDLAPHLKPLIGPWWFSQFDSIYEVSQAAKRSFQTAFPSQEKRVDALMFYSTEIFTYIEENLKLTPQSLSDKATASDELEEMHQQVLSSSLLAVTALYDIFFARSGSEYVTGESKYGVKARSIAL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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