Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G001755`

染色体: Chr01 坐标: 32270976-32277758 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G001755`
名称	SmilChr01G001755
描述	pleiotropic drug resistance protein 2-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	32270976 - 32277758 / `-`

ID 对照

NCBI Gene ID	`LOC131020180`
GeneID	`131020180`
locus_tag	`-`
NCBI Name	`LOC131020180`
原始查询	`SmilChr01G001755`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pleiotropic drug resistance protein 2-like
产物	pleiotropic drug resistance protein 2-like
Arabidopsis	`AT2G36380` (ABCG34) pleiotropic drug resistance 6 [Source:NCBI gene (formerly Entrezgene);Acc:818211] identity=70.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os07g0522500` (ABCG43) - identity=61.6; qcov=1.01; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0016020 (membrane); GO:0016887 (ATP hydrolysis activity); GO:0140359 (ABC-type transporter activity)
KEGG	smil02010 (ABC transporters - Salvia miltiorrhiza (redroot sage))
Pfam	PF00005 (ABC_tran); PF01061 (ABC2_membrane); PF08370 (PDR_assoc); PF14510 (ABC_trans_N); PF19055 (ABC2_membrane_7)
InterPro	-
eggNOG	-
NR	GeneID:131020180

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057804858.1`
2	Nucleus	细胞核	0.00000	`XP_057804858.1`
3	Chromosome	染色体	0.00000	`XP_057804858.1`
4	Centromere	着丝粒	0.00000	`XP_057804858.1`
5	Chromatin	染色质	0.00000	`XP_057804858.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:32271580`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B122,B124,B41,B52
`Chr1:32271779`	`A`	`ATT`	2bp_insertion	stop_gained,frameshift_variant	1	B3
`Chr1:32271779`	`A`	`ATT`	2bp_insertion	CDS_variant	1	B3
`Chr1:32271781`	`T`	`TG`	1bp_insertion	frameshift_variant	1	B3
`Chr1:32271781`	`T`	`TG`	1bp_insertion	CDS_variant	1	B3
`Chr1:32271784`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B3
`Chr1:32271793`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B3,B78,D1
`Chr1:32271950`	`ATC`	`A`	2bp_deletion	frameshift_variant	1	B136
`Chr1:32271950`	`ATC`	`A`	2bp_deletion	CDS_variant	1	B136
`Chr1:32272382`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C49,C77
`Chr1:32272853`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	B15
`Chr1:32272853`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B15

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804858.1

1444 aa

722

1444

ABC_trans_N

ABC_tran

ABC2_membrane_7

ABC2_membrane

PDR_assoc

ABC_tran

ABC2_membrane_7

ABC2_membrane

PF14510 ABC_trans_N 107-156 aa PF00005 ABC_tran 182-363 aa PF19055 ABC2_membrane_7 397-448 aa PF01061 ABC2_membrane 518-730 aa PF08370 PDR_assoc 735-800 aa PF00005 ABC_tran 868-1020 aa PF19055 ABC2_membrane_7 1049-1114 aa PF01061 ABC2_membrane 1165-1379 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804858.1`	Pfam	`PF14510`	ABC_trans_N	Domain	107	156	5e-11	43.5	ABC-transporter N-terminal
`XP_057804858.1`	Pfam	`PF00005`	ABC_tran	Domain	182	363	5.4e-38	131.4	ABC transporter
`XP_057804858.1`	Pfam	`PF19055`	ABC2_membrane_7	Family	397	448	7.6e-15	55.4	ABC-2 type transporter
`XP_057804858.1`	Pfam	`PF01061`	ABC2_membrane	Domain	518	730	2.7e-98	328.4	ABC-2 type transporter
`XP_057804858.1`	Pfam	`PF08370`	PDR_assoc	Family	735	800	2.1e-27	95.3	Plant PDR ABC transporter associated
`XP_057804858.1`	Pfam	`PF00005`	ABC_tran	Domain	868	1020	5.4e-38	131.4	ABC transporter
`XP_057804858.1`	Pfam	`PF19055`	ABC2_membrane_7	Family	1049	1114	7.6e-15	55.4	ABC-2 type transporter
`XP_057804858.1`	Pfam	`PF01061`	ABC2_membrane	Domain	1165	1379	2.7e-98	328.4	ABC-2 type transporter

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057948875.1
ACACAGCATCCCATGCCAACCAAATGGAGGAAATTCAACGCAACTGTGAGAGAGTCTTCACACACACACACATATATATATACATGTTTGTATAGCTACGAAGAAAAAATATCCAACTCAAAACTCCAAAAACATAGTAAGAGAGAGAGAGAGAGAAGGGAGAAAAACTGCATGGCAACTTGATTTTCAATCTTTCACACTACAAAGAAATTACACACCACCGATTCTTTCATTCATTTAAACAACAAAAAATCTCTACA...

CDS

1 records

下载 CDS FASTA

LOC131020180
ATGGCGGCGGCGCTGGCGGGGGACGATCTGTCTCGGACGACGAGCAGCAAGCGGAGCTGGCGGCAGCAGAGCATAAGAGACGTGTGGCAGGGGCCGCCGGACGTGTTCATGAGGAGCAGCACGCGGCGGCAGGCGGAGGACGACGAGGAGGAGCTGCGGTGGGCTGCCATCGAGCGCCTCCCGACGTACGACCGCCTCCGCAAGGGCGTGCTGCAGCAGGTGGTCAGCAATGGCAGGATCGTCCACTCCGAAGTCGACGT...

Protein

1 records

下载 Protein FASTA

XP_057804858.1
MAAALAGDDLSRTTSSKRSWRQQSIRDVWQGPPDVFMRSSTRRQAEDDEEELRWAAIERLPTYDRLRKGVLQQVVSNGRIVHSEVDVANLGSQDKKQLMESILKVVEEDNEKFLQRLRNRTDRVGIEIPKIEVRFQNLSIEGDAYVGTRALPTLLNSTINTLEACLGMIRLSPSKKRMVQILRNVSGVVKPSRMTLLLGPPGSGKTTLLKALTGKPDDDMKVTGKITYCGHEFHEFVPQRTCAYISQHDLHYGEMTVRET...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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