Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G001950`

染色体: Chr01 坐标: 34721183-34724427 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G001950`
名称	SmilChr01G001950
描述	receptor-like kinase TMK3
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	34721183 - 34724427 / `+`

ID 对照

NCBI Gene ID	`LOC131022109`
GeneID	`131022109`
locus_tag	`-`
NCBI Name	`LOC131022109`
原始查询	`SmilChr01G001950`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	receptor-like kinase TMK3
产物	receptor-like kinase TMK3
Arabidopsis	`AT2G01820` (AT2G01820) Leucine-rich repeat protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:814713] identity=45.4; qcov=1; evalue=0; confidence=high
Rice	`Os04g0685900` (OsRLCK174) - identity=48; qcov=1.03; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	-
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2)
InterPro	-
eggNOG	-
NR	GeneID:131022109

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057807494.1`
2	Nucleus	细胞核	0.00000	`XP_057807494.1`
3	Chromosome	染色体	0.00000	`XP_057807494.1`
4	Centromere	着丝粒	0.00000	`XP_057807494.1`
5	Chromatin	染色质	0.00000	`XP_057807494.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:34721727`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr1:34721730`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B129
`Chr1:34721778`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B125,B90,B92,D6
`Chr1:34721790`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:34721940`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:34722423`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr1:34722442`	`G`	`GA`	1bp_insertion	frameshift_variant	172	A1,A10,A18,A19,A2,A20,A22,A23,A25,A3,A4,A6,A7,A8,A9,B100,B102,B103,B104,B105,B106,B107,B108,B109,B110,B112,B113,B114,B115,B117,B118,B119,B122,B124,B125,B13,B132,B133,B136,B137,B138,B139,B140,B15,B16,B17,B18,B19,B20,B21,B22,B23,B24,B25,B27,B28,B29,B3,B30,B31,B32,B33,B34,B36,B37,B38,B4,B40,B41,B42,B43,B44,B45,B46,B48,B50,B52,B53,B54,B55,B56,B57,B59,B61,B62,B63,B64,B65,B68,B70,B71,B73,B74,B75,B79,B8,B80,B81,B82,B85,B87,B88,B89,B90,B92,B94,B96,B97,B98,B99,C10,C11,C12,C14,C15,C16,C18,C2,C21,C22,C24,C26,C27,C28,C3,C32,C35,C36,C37,C39,C4,C40,C41,C42,C43,C47,C5,C51,C53,C55,C57,C58,C61,C63,C64,C65,C66,C68,C69,C7,C71,C72,C73,C74,C75,C76,C78,C8,C81,C82,C83,C85,C86,C87,C9,D1,D10,D2,D4,D5,D8,D9
`Chr1:34722445`	`AG`	`A`	1bp_deletion	frameshift_variant	171	A1,A10,A18,A19,A2,A20,A22,A23,A25,A3,A4,A6,A7,A8,A9,B100,B102,B103,B104,B105,B106,B107,B108,B109,B110,B112,B113,B114,B115,B117,B118,B119,B122,B124,B125,B13,B132,B133,B136,B137,B138,B139,B140,B15,B16,B17,B18,B19,B20,B21,B22,B23,B24,B25,B27,B28,B29,B3,B30,B31,B32,B33,B34,B36,B37,B4,B40,B41,B42,B43,B44,B45,B46,B48,B5,B50,B52,B53,B54,B55,B56,B57,B59,B61,B62,B63,B64,B65,B68,B70,B71,B73,B74,B75,B79,B8,B80,B81,B82,B85,B87,B88,B89,B90,B92,B94,B96,B97,B98,B99,C10,C11,C12,C14,C15,C16,C18,C2,C21,C22,C24,C26,C27,C28,C3,C32,C35,C36,C37,C39,C4,C40,C41,C42,C43,C47,C51,C53,C55,C57,C58,C61,C63,C64,C65,C66,C68,C69,C7,C71,C72,C73,C74,C75,C76,C78,C8,C81,C82,C83,C85,C86,C87,C9,D1,D10,D2,D4,D5,D8,D9
`Chr1:34722579`	`T`	`TA`	1bp_insertion	frameshift_variant	172	A1,A10,A11,A18,A19,A2,A20,A21,A22,A23,A25,A3,A4,A6,A7,A8,A9,B102,B103,B104,B105,B106,B107,B108,B109,B110,B112,B113,B114,B115,B117,B118,B119,B122,B124,B125,B13,B133,B136,B137,B138,B139,B140,B15,B16,B17,B18,B19,B20,B21,B22,B23,B24,B25,B27,B28,B29,B3,B30,B31,B32,B33,B35,B36,B37,B4,B40,B41,B42,B43,B44,B45,B46,B48,B5,B50,B52,B53,B54,B55,B56,B57,B59,B61,B62,B63,B64,B65,B68,B70,B71,B73,B74,B75,B79,B8,B80,B81,B82,B85,B87,B88,B89,B90,B92,B94,B96,B97,B98,B99,C10,C11,C12,C14,C15,C16,C18,C2,C21,C22,C24,C26,C27,C28,C3,C32,C35,C36,C37,C39,C4,C40,C41,C42,C43,C47,C48,C51,C53,C55,C57,C58,C61,C63,C64,C65,C66,C68,C69,C7,C71,C72,C73,C74,C75,C76,C78,C8,C81,C82,C83,C85,C86,C87,C9,D1,D10,D2,D4,D5,D8,D9
`Chr1:34722581`	`GA`	`G`	1bp_deletion	frameshift_variant	172	A1,A10,A11,A18,A19,A2,A20,A21,A22,A23,A25,A3,A4,A6,A7,A8,A9,B102,B103,B104,B105,B106,B107,B108,B109,B110,B112,B113,B114,B115,B117,B118,B119,B122,B124,B125,B13,B133,B136,B137,B138,B139,B140,B15,B16,B17,B18,B19,B20,B21,B22,B23,B24,B25,B27,B28,B29,B3,B30,B31,B32,B33,B35,B36,B37,B4,B40,B41,B42,B43,B44,B45,B46,B48,B5,B50,B52,B53,B54,B55,B56,B57,B59,B61,B62,B63,B64,B65,B68,B70,B71,B73,B74,B75,B79,B8,B80,B81,B82,B85,B87,B88,B89,B90,B92,B94,B96,B97,B98,B99,C10,C11,C12,C14,C15,C16,C18,C2,C21,C22,C24,C26,C27,C28,C3,C32,C35,C36,C37,C39,C4,C40,C41,C42,C43,C47,C48,C51,C53,C55,C57,C58,C61,C63,C64,C65,C66,C68,C69,C7,C71,C72,C73,C74,C75,C76,C78,C8,C81,C82,C83,C85,C86,C87,C9,D1,D10,D2,D4,D5,D8,D9
`Chr1:34722614`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B81,C20,C75
`Chr1:34722644`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807494.1

862 aa

431

862

LRRNT_2

LRR_1

LRRNT_2

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 17-51 aa PF00560 LRR_1 177-197 aa PF00560 LRR_1 227-248 aa PF00560 LRR_1 250-272 aa PF08263 LRRNT_2 313-352 aa PF00069 Pkinase 541-809 aa PF07714 PK_Tyr_Ser-Thr 542-746 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807494.1`	Pfam	`PF08263`	LRRNT_2	Family	17	51	7.4e-06	26.9	Leucine rich repeat N-terminal domain
`XP_057807494.1`	Pfam	`PF00560`	LRR_1	Repeat	177	197	1.6e-16	57.5	Leucine Rich Repeat
`XP_057807494.1`	Pfam	`PF00560`	LRR_1	Repeat	227	248	1.6e-16	57.5	Leucine Rich Repeat
`XP_057807494.1`	Pfam	`PF00560`	LRR_1	Repeat	250	272	1.6e-16	57.5	Leucine Rich Repeat
`XP_057807494.1`	Pfam	`PF08263`	LRRNT_2	Family	313	352	7.4e-06	26.9	Leucine rich repeat N-terminal domain
`XP_057807494.1`	Pfam	`PF00069`	Pkinase	Domain	541	809	5.7e-42	144.6	Protein kinase domain
`XP_057807494.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	542	746	3.1e-40	138.8	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057951511.1
AATTCTTAAAAATCTCAAGAAAGATCAGAACAACTCAAACGAGAAATGGGGAGAGGTGCAGTGATGACGACAGAATTTATGTTCAAATCGAGTTTAGGGTTTGAGCATTCAAACTGTCACCACTCAAAACCCCCAAACAAGAAACGGAAACCATGCAAATTCTCCCGCATCTCATCCTTTTCTCAATTTATTGCCTAAACAAAATTAATAATCCATAATAAAACCCTACCAATCCGTTTTTGGAAGAAATCTGCATGCAT...

CDS

1 records

下载 CDS FASTA

LOC131022109
ATGCAACAGCTCATCACTCATCACTCATCACTCATCACCACCAAGATTCTGAGTGATTTCAGAAACGGTTTGGAAAATCCAGATCTTCTGAAATGGCCTAAAACCGGCAACGATCCATGCGGGCCCCTGATCTGGCCCCACATTGGCTGCTCCAACGGCAGAGTGATCTCGATCCAAGTTTCGGGCCTCGGGCTGACGGGCCCGTTGCCCCCGAATCTGAATCAGCTAAGCGAGCTCAAGAATCTTAGCTTGCAGAAGAA...

Protein

1 records

下载 Protein FASTA

XP_057807494.1
MQQLITHHSSLITTKILSDFRNGLENPDLLKWPKTGNDPCGPLIWPHIGCSNGRVISIQVSGLGLTGPLPPNLNQLSELKNLSLQKNYFNGNLPSFSGLSNLQHAYLNSNEFETIPLDFFHGLSNVMVIALDYNPLNQSSGWALPHDLAECTRLVNFSCSFCNIIGEIPLFFGKLSSLNSLRLSSNRLSGGIPSSFHGSLLQILWLNDQENGGMNGSISVVGSMVLLTQLWLHGNQFTGPIPDTIGYLASLRELNVNGNQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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