Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G002391`

染色体: Chr01 坐标: 41176170-41179598 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G002391`
名称	SmilChr01G002391
描述	L-lactate dehydrogenase A-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	41176170 - 41179598 / `+`

ID 对照

NCBI Gene ID	`LOC131025029`
GeneID	`131025029`
locus_tag	`-`
NCBI Name	`LOC131025029`
原始查询	`SmilChr01G002391`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	L-lactate dehydrogenase A-like
产物	L-lactate dehydrogenase A-like
Arabidopsis	`AT4G17260` (AT4G17260) Lactate/malate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:827440] identity=78.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os02g0105400` (LDH) - identity=69.4; qcov=0.989; evalue=1.22e-168; confidence=high
GO	GO:0004459 (L-lactate dehydrogenase (NAD+) activity); GO:0005737 (cytoplasm); GO:0019752 (carboxylic acid metabolic process)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00056 (Ldh_1_N); PF02866 (Ldh_1_C)
InterPro	-
eggNOG	-
NR	GeneID:131025029

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057810598.1`
2	Cytosol	细胞质基质	0.80000	`XP_057810598.1`
3	Nucleus	细胞核	0.40000	`XP_057810598.1`
4	Chromosome	染色体	0.00000	`XP_057810598.1`
5	Centromere	着丝粒	0.00000	`XP_057810598.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:41176494`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A8,B126,B61,B65,C2
`Chr1:41176563`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr1:41176611`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B22,B41
`Chr1:41176628`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D8
`Chr1:41176683`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B3,C18
`Chr1:41176717`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr1:41176770`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B22,B41
`Chr1:41176800`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B22,B41
`Chr1:41176843`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C79
`Chr1:41176858`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C17,C20,C61
`Chr1:41176903`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C75
`Chr1:41179066`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B33,C25

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057810598.1

350 aa

175

350

Ldh_1_N

Ldh_1_C

PF00056 Ldh_1_N 38-177 aa PF02866 Ldh_1_C 180-343 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057810598.1`	Pfam	`PF00056`	Ldh_1_N	Domain	38	177	9.8e-45	152.8	lactate/malate dehydrogenase, NAD binding domain
`XP_057810598.1`	Pfam	`PF02866`	Ldh_1_C	Domain	180	343	1.1e-32	114.1	lactate/malate dehydrogenase, alpha/beta C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057954615.1
CATAAATTCGAGTAGATGCATTAAAAAAAAAAAAAGAAAAAAAAGGAGCATATTTAGGAGTAGGACCCGGGTCTTAGTTGGACCAATAGTAAAGAAGCAGGCCCATGGTAATGCCCATACCCACAGCAATGCCATTTTTTATCTCCCACAAATAGAAGTCTCCCAATACCGTTGACCGTTGAGAGCAAACCCCCATCACCACCACCACCACCACTTCTCCTCCGCCTCACACCACCACTTCACTTGTATATATATATATA...

CDS

1 records

下载 CDS FASTA

LOC131025029
ATGCATAAGGCGTCATCCTCCTCCGCCCTCGGCCCCGACGGCCTGGACCTCTCAAAAACCTTCTTCACCCCCATCGACGGCGGCGCCCCCACGTCCCCCACGAAGCGCAACACGAAGATCACGGTGGTGGGCGTGGGCAACGTGGGCATGGCCATCGCCCAGACCATCATCACCCAGGACCTCGCCGACGAGCTCACCCTCGTGGACGCCAAGGAGGACAAGCTCCGCGGCGAGGTCCTCGACCTCCAACACGCCGCCGC...

Protein

1 records

下载 Protein FASTA

XP_057810598.1
MHKASSSSALGPDGLDLSKTFFTPIDGGAPTSPTKRNTKITVVGVGNVGMAIAQTIITQDLADELTLVDAKEDKLRGEVLDLQHAAAFLPRVKINASLDYAETAHSDLCIVTAGARQNPGESRLNLLQRNVALFKHIVPPLAKYSPDCIILVVSNPVDLLTYVAWKLSGFPANRVLGSGTNLDSSRFRFLIADHLDVNAQDVQAYIVGEHGDSSVALWSSISVGGVPVLSFLERQQIPYEKKTLESIHKEVVQGAYEVIR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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