Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G002821`

染色体: Chr01 坐标: 46765440-46769409 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G002821`
名称	SmilChr01G002821
描述	replication protein A 70 kDa DNA-binding subunit A
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	46765440 - 46769409 / `-`

ID 对照

NCBI Gene ID	`LOC130987221`
GeneID	`130987221`
locus_tag	`-`
NCBI Name	`LOC130987221`
原始查询	`SmilChr01G002821`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	replication protein A 70 kDa DNA-binding subunit A
产物	replication protein A 70 kDa DNA-binding subunit A
Arabidopsis	`AT2G06510` (RPA1A) replication protein A 1A [Source:NCBI gene (formerly Entrezgene);Acc:815209] identity=68.2; qcov=1; evalue=0; confidence=high
Rice	`Os02g0776800` (RPA1A) - identity=60.4; qcov=1.02; evalue=0; confidence=high
GO	GO:0000724 (double-strand break repair via homologous recombination); GO:0003684 (damaged DNA binding); GO:0005634 (nucleus); GO:0005662 (DNA replication factor A complex); GO:0006260 (DNA replication); GO:0006268 (GO:0006268); GO:0006289 (nucleotide-excision repair); GO:0007004 (telomere maintenance via telomerase); GO:0043047 (single-stranded telomeric DNA binding); GO:0051321 (meiotic cell cycle)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage)); smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage)); smil03430 (Mismatch repair - Salvia miltiorrhiza (redroot sage)); smil03440 (Homologous recombination - Salvia miltiorrhiza (redroot sage)); smil03460 (Fanconi anemia pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF01336 (tRNA_anti-codon); PF04057 (Rep-A_N); PF08646 (Rep_fac-A_C); PF16900 (REPA_OB_2)
InterPro	-
eggNOG	-
NR	GeneID:130987221

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057766867.1`
2	Chromosome	染色体	0.40000	`XP_057766867.1`
3	Centromere	着丝粒	0.00000	`XP_057766867.1`
4	Chromatin	染色质	0.00000	`XP_057766867.1`
5	Telomere	端粒	0.00000	`XP_057766867.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:46766184`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B30,C16,C32,C68
`Chr1:46766334`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,D11
`Chr1:46766366`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C12
`Chr1:46766478`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:46766563`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:46766668`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B83,C46
`Chr1:46766716`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr1:46766871`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B86
`Chr1:46766892`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B14,B15,C26
`Chr1:46766945`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B137
`Chr1:46767012`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C40
`Chr1:46767289`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B83,C46

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057766867.1

638 aa

319

638

Rep-A_N

tRNA_anti-codon

REPA_OB_2

Rep_fac-A_C

PF04057 Rep-A_N 5-97 aa PF01336 tRNA_anti-codon 204-281 aa PF16900 REPA_OB_2 312-416 aa PF08646 Rep_fac-A_C 474-625 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057766867.1`	Pfam	`PF04057`	Rep-A_N	Domain	5	97	1.8e-29	102.5	Replication factor-A protein 1, N-terminal domain
`XP_057766867.1`	Pfam	`PF01336`	tRNA_anti-codon	Domain	204	281	2.1e-10	41.1	OB-fold nucleic acid binding domain
`XP_057766867.1`	Pfam	`PF16900`	REPA_OB_2	Domain	312	416	9.4e-28	96.8	Replication protein A OB domain
`XP_057766867.1`	Pfam	`PF08646`	Rep_fac-A_C	Domain	474	625	2.3e-51	174.2	Replication factor-A C terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057910884.1
CTATATAAAATGTCAAATTTATAATGCCGAATTTCGCTAAAATCACCTAATTTAAATAGATTTGATATAAGTGTTGTTAGCAATGGGCACATCCTCAAATGTGGGTAGGTCGGTTTGTTTGTTCTCCCCGCCTTGGCTCAAAATACCACCCCCAAACTCCTCGTATATATATAATCTGACCTCCTTTCTTGTTCGAAATTCTTCCACGATTTCCCCCTTCCCCACCCTCTCCATTTCAGTATACTTTCCTACGAAATCAC...

CDS

1 records

下载 CDS FASTA

LOC130987221
ATGCCGGTGAATTTGACGGCCAACGCTATTGCGGCAATAATCGGCGGAGACGTCAACGCGAAGCCGCTGGTGCAGGTGTTGGAAATCAAGCTCATCGGCTCCACGCAGGAGCGTTACCGCCTTATCATATCCGACGCGGTGGCTACTGAGCAAGCTATGCTCGCCTCGCAGCTCAATGACCGAGTTAAGACCGGCCGAATCCGCAAGGGATCCGTCATCCAGCTCATCGAATACATCTGCAGTCCCGTCCAGAACCGCAA...

Protein

1 records

下载 Protein FASTA

XP_057766867.1
MPVNLTANAIAAIIGGDVNAKPLVQVLEIKLIGSTQERYRLIISDAVATEQAMLASQLNDRVKTGRIRKGSVIQLIEYICSPVQNRKIIVVLNMETIIPDCDVIGNPMYSESDSVPGKPASSGPRPSINNSVSGAHNSSRTSYNNGKTSSSLNQGGMQSFHPTVQPPYQPPPNYKNHGAIMRNEAPARIIPIAALNPYQGRWAIKARVTAKGDLRRYNNARGDGKVFSFDLLDSDGGEIRVTCFNAVVDRFYDTIDVGKV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器