Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003462`

染色体: Chr01 坐标: 53203843-53208512 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003462`
名称	SmilChr01G003462
描述	probable prolyl 4-hydroxylase 3
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	53203843 - 53208512 / `+`

ID 对照

NCBI Gene ID	`LOC130993070`
GeneID	`130993070`
locus_tag	`-`
NCBI Name	`LOC130993070`
原始查询	`SmilChr01G003462`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable prolyl 4-hydroxylase 3
产物	probable prolyl 4-hydroxylase 3
Arabidopsis	`AT1G20270` (AT1G20270) 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:838615] identity=74.3; qcov=1.01; evalue=1.2e-164; confidence=high
Rice	`Os10g0497800` - identity=81.7; qcov=0.758; evalue=1.93e-128; confidence=high
GO	GO:0004656 (procollagen-proline 4-dioxygenase activity); GO:0005506 (iron ion binding); GO:0005783 (endoplasmic reticulum); GO:0018401 (peptidyl-proline hydroxylation to 4-hydroxy-L-proline); GO:0031418 (L-ascorbic acid binding)
KEGG	smil00330 (Arginine and proline metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF03171 (2OG-FeII_Oxy); PF13640 (2OG-FeII_Oxy_3)
InterPro	-
eggNOG	-
NR	GeneID:130993070

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	1.00000	`XP_057773778.1`
2	Nucleus	细胞核	0.00000	`XP_057773778.1`
3	Chromosome	染色体	0.00000	`XP_057773778.1`
4	Centromere	着丝粒	0.00000	`XP_057773778.1`
5	Chromatin	染色质	0.00000	`XP_057773778.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:53204180`	`TG`	`T`	1bp_deletion	frameshift_variant	1	B26
`Chr1:53204180`	`TG`	`T`	1bp_deletion	CDS_variant	1	B26
`Chr1:53204330`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C56
`Chr1:53206144`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B32

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773778.1

289 aa

144

289

2OG-FeII_Oxy

2OG-FeII_Oxy_3

PF03171 2OG-FeII_Oxy 166-283 aa PF13640 2OG-FeII_Oxy_3 168-283 aa

XP_057773785.1

289 aa

144

289

2OG-FeII_Oxy

2OG-FeII_Oxy_3

PF03171 2OG-FeII_Oxy 166-283 aa PF13640 2OG-FeII_Oxy_3 168-283 aa

XP_057773791.1

289 aa

144

289

2OG-FeII_Oxy

2OG-FeII_Oxy_3

PF03171 2OG-FeII_Oxy 166-283 aa PF13640 2OG-FeII_Oxy_3 168-283 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773778.1`	Pfam	`PF03171`	2OG-FeII_Oxy	Domain	166	283	5.3e-09	37.0	2OG-Fe(II) oxygenase superfamily
`XP_057773778.1`	Pfam	`PF13640`	2OG-FeII_Oxy_3	Domain	168	283	4.3e-19	70.0	2OG-Fe(II) oxygenase superfamily
`XP_057773785.1`	Pfam	`PF03171`	2OG-FeII_Oxy	Domain	166	283	5.3e-09	37.0	2OG-Fe(II) oxygenase superfamily
`XP_057773785.1`	Pfam	`PF13640`	2OG-FeII_Oxy_3	Domain	168	283	4.3e-19	70.0	2OG-Fe(II) oxygenase superfamily
`XP_057773791.1`	Pfam	`PF03171`	2OG-FeII_Oxy	Domain	166	283	5.3e-09	37.0	2OG-Fe(II) oxygenase superfamily
`XP_057773791.1`	Pfam	`PF13640`	2OG-FeII_Oxy_3	Domain	168	283	4.3e-19	70.0	2OG-Fe(II) oxygenase superfamily

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057917802.1
AAAACTACTGCGTGCGTTTTCGCAATTTGACGGCTTCCGATTCAACTCCTCCTCACGTATTGAATTTCTCCATTTTCAGATAATTTCAAATTCTAAATGCTACAAAACAAAACAGCCTAGAGGAATTCGATAAATCGTTTGCCCATTAATTGGGGTTGTAATTCAATTCAGTTTCAGCTCACAGAAAAACGAAAATGGCGAAGGGGCGAGGAAATCGGCACCAGGGCAAGAGATCGTCTACTGTAGTTTTGGTGCTCTCG...

XM_057917795.1
TGCGTTTTCGCAATTTGACGGCTTCCGATTCAACTCCTCCTCACGTATTGAATTTCTCCATTTTCAGATAATTTCAAATTCTAAATGCTACAAAACAAAACAGCCTAGAGGAATTCGATAAATCGTTTGCCCATTAATTGGGGTTGTAATTCAATTCAGTTTCAGCTCACAGAAAAACGAAAATGGCGAAGGGGCGAGGAAATCGGCACCAGGGCAAGAGATCGTCTACTGTAGTTTTGGTGCTCTCGATGCTATTAATG...

CDS

3 records

下载 CDS FASTA

LOC130993070
ATGGCGAAGGGGCGAGGAAATCGGCACCAGGGCAAGAGATCGTCTACTGTAGTTTTGGTGCTCTCGATGCTATTAATGCTATCAGTCGTGCTGCTGATGCTTCTCGGTCTAGGAATTCTCTCTCTCCCCATTGGCTCCGATGATGGATTGTCAGCGATCGGAGATCACATCAAATTGAAACGCTTAAAAATAGACGTAAAAAACGAAGGAAATGGATTGGGGGAGAGAACGGAGCAGTGGAGTGAGATCCTGTCGTGGGA...

Protein

3 records

下载 Protein FASTA

XP_057773778.1
MAKGRGNRHQGKRSSTVVLVLSMLLMLSVVLLMLLGLGILSLPIGSDDGLSAIGDHIKLKRLKIDVKNEGNGLGERTEQWSEILSWEPRAFLYHNFLSKEECEYLINLAKPHMVKSTVVDSKTGKSKDSRVRTSSGTFLRRGRDKVIRNIEKRIADYTFIPAEHGEGLQILHYEVGQKYEPHYDYFLDEFNTKNGGQRIATVLMYLSDVEEGGETIFPAAKGNFSSSLGLSECGKQGLAVKPKMGDALLFWSMRPDASLD...

XP_057773785.1
MAKGRGNRHQGKRSSTVVLVLSMLLMLSVVLLMLLGLGILSLPIGSDDGLSAIGDHIKLKRLKIDVKNEGNGLGERTEQWSEILSWEPRAFLYHNFLSKEECEYLINLAKPHMVKSTVVDSKTGKSKDSRVRTSSGTFLRRGRDKVIRNIEKRIADYTFIPAEHGEGLQILHYEVGQKYEPHYDYFLDEFNTKNGGQRIATVLMYLSDVEEGGETIFPAAKGNFSSSLGLSECGKQGLAVKPKMGDALLFWSMRPDASLD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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