Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003888`

染色体: Chr01 坐标: 57198320-57204154 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003888`
名称	SmilChr01G003888
描述	2-isopropylmalate synthase A-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	57198320 - 57204154 / `+`

ID 对照

NCBI Gene ID	`LOC130997644`
GeneID	`130997644`
locus_tag	`-`
NCBI Name	`LOC130997644`
原始查询	`SmilChr01G003888`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	2-isopropylmalate synthase A-like
产物	2-isopropylmalate synthase A-like
Arabidopsis	`AT1G74040` (IMS1) 2-isopropylmalate synthase 1 [Source:NCBI gene (formerly Entrezgene);Acc:843742] identity=73.3; qcov=0.939; evalue=0; confidence=high
Rice	`Os11g0142500` (OsIPMS1) - identity=72.7; qcov=0.955; evalue=0; confidence=high
GO	GO:0003852 (2-isopropylmalate synthase activity); GO:0009098 (L-leucine biosynthetic process); GO:0009507 (chloroplast)
KEGG	smil00290 (Valine, leucine and isoleucine biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00682 (HMGL-like); PF08502 (LeuA_dimer); PF22617 (HCS_D2)
InterPro	-
eggNOG	-
NR	GeneID:130997644

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057779024.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057779024.1`
3	Nucleus	细胞核	0.00000	`XP_057779024.1`
4	Chromosome	染色体	0.00000	`XP_057779024.1`
5	Centromere	着丝粒	0.00000	`XP_057779024.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:57198582`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr1:57198667`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C40
`Chr1:57198680`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B69
`Chr1:57198685`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr1:57198700`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A22,C71
`Chr1:57198714`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C5
`Chr1:57198743`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C19,C4
`Chr1:57198813`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B56,B96,C25
`Chr1:57198818`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C5
`Chr1:57198846`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C56
`Chr1:57198870`	`AG`	`A`	1bp_deletion	frameshift_variant	1	C9
`Chr1:57198870`	`AG`	`A`	1bp_deletion	CDS_variant	1	C9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057779024.1

632 aa

316

632

HMGL-like

HCS_D2

LeuA_dimer

PF00682 HMGL-like 57-334 aa PF22617 HCS_D2 348-432 aa PF08502 LeuA_dimer 434-546 aa

XP_057779030.1

594 aa

297

594

HMGL-like

HCS_D2

LeuA_dimer

PF00682 HMGL-like 57-334 aa PF22617 HCS_D2 348-432 aa PF08502 LeuA_dimer 434-574 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057779024.1`	Pfam	`PF00682`	HMGL-like	Domain	57	334	3.9e-93	312.3	HMGL-like
`XP_057779024.1`	Pfam	`PF22617`	HCS_D2	Domain	348	432	5.2e-28	98.0	Homocitrate synthase post-HMGL domain-like
`XP_057779024.1`	Pfam	`PF08502`	LeuA_dimer	Domain	434	546	6.5e-25	88.3	LeuA allosteric (dimerisation) domain
`XP_057779030.1`	Pfam	`PF00682`	HMGL-like	Domain	57	334	3.4e-93	312.5	HMGL-like
`XP_057779030.1`	Pfam	`PF22617`	HCS_D2	Domain	348	432	4.2e-28	98.3	Homocitrate synthase post-HMGL domain-like
`XP_057779030.1`	Pfam	`PF08502`	LeuA_dimer	Domain	434	574	4.4e-31	108.2	LeuA allosteric (dimerisation) domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057923041.1
ATGGTGATCGATATTATTAGAAGATTAAAAAATCATGTTAAAATTGTAAAGCGATAAGAGTATATGACATGCGTGAGCGTCAAACTCAAACTCCTTCATCACCATTCACTACCACTTTTCAAACCCAAAATTCCTTCCTAAATTTTCCACATCAATGGCTGCTTCCATTTGCATTTCCCGCCACCCAATCCGAGCACCGCTCTCCGACTTATTCCCCCCAAACACAGTCCTCCTCCGCTTCACAAACCTCAGAACCGCCG...

XM_057923047.1
ATGGTGATCGATATTATTAGAAGATTAAAAAATCATGTTAAAATTGTAAAGCGATAAGAGTATATGACATGCGTGAGCGTCAAACTCAAACTCCTTCATCACCATTCACTACCACTTTTCAAACCCAAAATTCCTTCCTAAATTTTCCACATCAATGGCTGCTTCCATTTGCATTTCCCGCCACCCAATCCGAGCACCGCTCTCCGACTTATTCCCCCCAAACACAGTCCTCCTCCGCTTCACAAACCTCAGAACCGCCG...

CDS

2 records

下载 CDS FASTA

LOC130997644
ATGGCTGCTTCCATTTGCATTTCCCGCCACCCAATCCGAGCACCGCTCTCCGACTTATTCCCCCCAAACACAGTCCTCCTCCGCTTCACAAACCTCAGAACCGCCGCCGTCCGGTGCTCCCTCCGACGTCCGGACTACGTCCCCAACCACATCCCGGACCCCAGCTACGTCCGCGTCTTCGACACCACCCTTCGCGATGGCGAGCAGTCCCCCGGCGCCACCATGACCGCCGAGGAGAAGCTCGGCATCGCCCGCCAGCT...

Protein

2 records

下载 Protein FASTA

XP_057779024.1
MAASICISRHPIRAPLSDLFPPNTVLLRFTNLRTAAVRCSLRRPDYVPNHIPDPSYVRVFDTTLRDGEQSPGATMTAEEKLGIARQLARLGVDVIEAGFPASSSADFDAVRMIAAEVGSADADHVPVICGLARCNERDIAMAWEAVKDAKKPRIHTFIATSEIHMNYKLKMTPQQVVDKARSMVAYARSLGCDDVEFSPEDAGRSDREFLYTILGEVIRAGATTLNIPDTVGYTLPTEFGQLIADIKANTPGIENVIIST...

XP_057779030.1
MAASICISRHPIRAPLSDLFPPNTVLLRFTNLRTAAVRCSLRRPDYVPNHIPDPSYVRVFDTTLRDGEQSPGATMTAEEKLGIARQLARLGVDVIEAGFPASSSADFDAVRMIAAEVGSADADHVPVICGLARCNERDIAMAWEAVKDAKKPRIHTFIATSEIHMNYKLKMTPQQVVDKARSMVAYARSLGCDDVEFSPEDAGRSDREFLYTILGEVIRAGATTLNIPDTVGYTLPTEFGQLIADIKANTPGIENVIIST...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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