Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004108`

染色体: Chr01 坐标: 59592529-59599790 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004108`
名称	SmilChr01G004108
描述	histone acetyltransferase GCN5
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	59592529 - 59599790 / `+`

ID 对照

NCBI Gene ID	`LOC130999516`
GeneID	`130999516`
locus_tag	`-`
NCBI Name	`LOC130999516`
原始查询	`SmilChr01G004108`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	histone acetyltransferase GCN5
产物	histone acetyltransferase GCN5
Arabidopsis	`AT3G54610` (HAG1) histone acetyltransferase of the GNAT family 1 [Source:NCBI gene (formerly Entrezgene);Acc:824626] identity=68; qcov=1.04; evalue=0; confidence=high
Rice	`Os10g0415900` (OsHAG702) - identity=66.2; qcov=0.967; evalue=0; confidence=high
GO	GO:0000123 (histone acetyltransferase complex); GO:0005515 (protein binding); GO:0006338 (chromatin remodeling); GO:0010484 (histone H3 acetyltransferase activity); GO:0043966 (GO:0043966); GO:0045944 (positive regulation of transcription by RNA polymerase II)
KEGG	smil03250 (Viral life cycle - HIV-1 - Salvia miltiorrhiza (redroot sage))
Pfam	PF00439 (Bromodomain); PF00583 (Acetyltransf_1); PF13508 (Acetyltransf_7); PF13673 (Acetyltransf_10)
InterPro	-
eggNOG	-
NR	GeneID:130999516

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057781043.1`
2	Chromosome	染色体	0.00000	`XP_057781043.1`
3	Centromere	着丝粒	0.00000	`XP_057781043.1`
4	Chromatin	染色质	0.00000	`XP_057781043.1`
5	Telomere	端粒	0.00000	`XP_057781043.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:59592803`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B118,C19
`Chr1:59592857`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C25,C46,C63
`Chr1:59592872`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B85
`Chr1:59592938`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B124,C61,C78
`Chr1:59593125`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B35
`Chr1:59593125`	`AC`	`A`	1bp_deletion	CDS_variant	1	B35
`Chr1:59593128`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B19,B35
`Chr1:59593163`	`TGA`	`T`	2bp_deletion	frameshift_variant	1	C2
`Chr1:59593163`	`TGA`	`T`	2bp_deletion	CDS_variant	1	C2
`Chr1:59593228`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B19,C43,C9,D4
`Chr1:59594363`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C25
`Chr1:59594620`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B45,C72

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781043.1

548 aa

274

548

Acetyltransf_1

Acetyltransf_10

Acetyltransf_7

Bromodomain

PF00583 Acetyltransf_1 236-321 aa PF13673 Acetyltransf_10 239-323 aa PF13508 Acetyltransf_7 243-322 aa PF00439 Bromodomain 444-525 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781043.1`	Pfam	`PF00583`	Acetyltransf_1	Family	236	321	1.2e-12	48.8	Acetyltransferase (GNAT) family
`XP_057781043.1`	Pfam	`PF13673`	Acetyltransf_10	Domain	239	323	3.1e-06	27.9	Acetyltransferase (GNAT) domain
`XP_057781043.1`	Pfam	`PF13508`	Acetyltransf_7	Domain	243	322	8.5e-07	30.0	Acetyltransferase (GNAT) domain
`XP_057781043.1`	Pfam	`PF00439`	Bromodomain	Domain	444	525	4.7e-22	78.5	Bromodomain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009093533.1
TGAAAAACATTGCAGTACTTTAGTTTAACCAGATACTAATATTTAACCGAAGTAGCAAAAAGCAATCATAAAATAGTTAGGGTAAATTGAATTGAACACATCCAATTTTGATTCATCTCTCCCAATTTCCCCCTTTTCTCTTGAAAAATATTCAATTCGAAAACTCAACTGTGGTTGTATAACGCCGAGATTCAGCAATGGACGGGCATTCGTCGCATTTGACGGCGCCGGTCCGTTCACGGAGCTCTCAGTCTCCGTCG...

XM_057925060.1
TTCAAAAAACAAAACTTATGGAATATTTCGAGTTTAAAGGGACCCAATTAAGTGATCATGTCTGATCCAAATTGAAAAACATTGCAGTACTTTAGTTTAACCAGATACTAATATTTAACCGAAGTAGCAAAAAGCAATCATAAAATAGTTAGGGTAAATTGAATTGAACACATCCAATTTTGATTCATCTCTCCCAATTTCCCCCTTTTCTCTTGAAAAATATTCAATTCGAAAACTCAACTGTGGTTGTATAACGCCGA...

CDS

1 records

下载 CDS FASTA

LOC130999516
ATGGACGGGCATTCGTCGCATTTGACGGCGCCGGTCCGTTCACGGAGCTCTCAGTCTCCGTCGCCATCCCACTCCGCGTCGGCTTCTGCCACCTCTTCCATCCACAAGCGCAAATTGCAGCCGGAAGACCACGCGCCGCCGTTTCCGCCGTCGTTCTCCGACACGCGCGACGGCCCGCTGACGTCGAACGACGACCTGGAGAGCAACAGCGTCCGCGGCGCCGACTCTGACTCCGACGAGGAGTCGGAGGAGGTCGTCGA...

Protein

1 records

下载 Protein FASTA

XP_057781043.1
MDGHSSHLTAPVRSRSSQSPSPSHSASASATSSIHKRKLQPEDHAPPFPPSFSDTRDGPLTSNDDLESNSVRGADSDSDEESEEVVDEEEEEYDNSMRNFTASRLESSNTAGPAARNTKIKAENSVKVEPSDAVKEGNINNSISGAAAATGANGSVPGIVVKEDTVKSIFTDNIQTSGAYSAREESLKREEEAGSLKFVCASNDGVDKHMIWLIGLKNIFARQLPNMPREYIVRLLMDRNHKSVMVIRRNTVVGGITYRP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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