Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004444`

染色体: Chr01 坐标: 62559170-62565033 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004444`
名称	SmilChr01G004444
描述	nonsense-mediated mRNA decay factor SMG7-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	62559170 - 62565033 / `+`

ID 对照

NCBI Gene ID	`LOC131002733`
GeneID	`131002733`
locus_tag	`-`
NCBI Name	`LOC131002733`
原始查询	`SmilChr01G004444`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	nonsense-mediated mRNA decay factor SMG7-like
产物	nonsense-mediated mRNA decay factor SMG7-like
Arabidopsis	`AT5G19400` (SMG7) Telomerase activating protein Est1 [Source:NCBI gene (formerly Entrezgene);Acc:832060] identity=49; qcov=0.735; evalue=0; confidence=high
Rice	`Os08g0305300` - identity=52; qcov=0.715; evalue=0; confidence=high
GO	GO:0000184 (nuclear-transcribed mRNA catabolic process, nonsense-mediated decay); GO:0005515 (protein binding); GO:0005697 (telomerase holoenzyme complex); GO:0042162 (telomeric repeat DNA binding); GO:0070034 (telomerase RNA binding)
KEGG	smil03015 (mRNA surveillance pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF10373 (EST1_DNA_bind); PF10374 (EST1)
InterPro	-
eggNOG	-
NR	GeneID:131002733

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057785187.1`
2	Cytoplasm	细胞质	0.40000	`XP_057785187.1`
3	P-body	P-body	0.20000	`XP_057785187.1`
4	Chromosome	染色体	0.00000	`XP_057785187.1`
5	Centromere	着丝粒	0.00000	`XP_057785187.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:62560604`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B13,B38,B39,B53
`Chr1:62560749`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B66
`Chr1:62561043`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B26,C40
`Chr1:62561312`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B124,B126,B61
`Chr1:62561321`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B117,B124,B126,B61
`Chr1:62561324`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B117,B124,B126,B61
`Chr1:62561917`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A2,B26
`Chr1:62562088`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B18
`Chr1:62562280`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B4,C36,D6
`Chr1:62562393`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B137
`Chr1:62562483`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B9
`Chr1:62562706`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057785187.1

974 aa

487

974

EST1

EST1_DNA_bind

PF10374 EST1 70-193 aa PF10373 EST1_DNA_bind 207-540 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057785187.1`	Pfam	`PF10374`	EST1	Repeat	70	193	1.3e-18	68.4	Telomerase activating protein Est1
`XP_057785187.1`	Pfam	`PF10373`	EST1_DNA_bind	Repeat	207	540	1.5e-53	182.9	Est1 DNA/RNA binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009094393.1
TAAAGCCCGAAAACTAAAAGGTACTCTCTCTCTATCTCTCTAAATTTGATCTTTTTTTCTCCCTCCAGCTCTTCGAAGCTCATCGCCAGAAAACCCCTCTAATTTTCATCAAGAGAAACCCTAATTCTAATAATCATAGAGAAACACCGATTTATCGCCTTCGTTCTTTCATCTTTGTGTGTGTATATATACAATTAGGGGTTTGTTGGATTCAGGGAAGTAAAGCGGTGTTGCGAGATCTTGGCAGATCCGGCGTCGTT...

XM_057929204.1
TAAAGCCCGAAAACTAAAAGGTACTCTCTCTCTATCTCTCTAAATTTGATCTTTTTTTCTCCCTCCAGCTCTTCGAAGCTCATCGCCAGAAAACCCCTCTAATTTTCATCAAGAGAAACCCTAATTCTAATAATCATAGAGAAACACCGATTTATCGCCTTCGTTCTTTCATCTTTGTGTGTGTATATATACAATTAGGGGTTTGTTGGATTCAGGGAAGTAAAGCGGTGTTGCGAGATCTTGGCAGATCCGGCGTCGTT...

CDS

1 records

下载 CDS FASTA

LOC131002733
ATGATGACAATTCCGATGGAAAATGAAAAAGAAAGCTCCTCAAGGGAGCTTGTAGAGAATCTCTTCAATAAGAACATTGAATTGGAGAAAAATAGAAGGAAAGCAGCGCAGGCCAGAGTCCCTTCAGATCCTAATACATGGCAACATATGCGTGAGAATTATGAAGCTATTGTTCTTGAAGACCATGCCTTCTCTGAGCAACATGATATCGAATATGCTCTATGGCAACTGCATTACAGGAAGATTGAGGAGCTAAGGGC...

Protein

1 records

下载 Protein FASTA

XP_057785187.1
MMTIPMENEKESSSRELVENLFNKNIELEKNRRKAAQARVPSDPNTWQHMRENYEAIVLEDHAFSEQHDIEYALWQLHYRKIEELRALFNAALTSAGSAASQNGKGPGRSGSDRLAKIRSQFKTFLSEATGFYHDLMLKIRAKYGLPLEYFSDGNQISMSKDGNKSSEVKKWLISCHRCLIYLGDLARYKGLYGGEGDSKARDFTAASTHYMQASSLCPSNGNAHHQLAILAGYSNDELVSIYRYFRSLAVDNPFITARD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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