Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004504`

染色体: Chr01 坐标: 63156204-63164130 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004504`
名称	SmilChr01G004504
描述	transcription elongation factor SPT6 homolog
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	63156204 - 63164130 / `+`

ID 对照

NCBI Gene ID	`LOC131003102`
GeneID	`131003102`
locus_tag	`-`
NCBI Name	`LOC131003102`
原始查询	`SmilChr01G004504`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	transcription elongation factor SPT6 homolog
产物	transcription elongation factor SPT6 homolog
Arabidopsis	`AT1G65440` (GTB1) global transcription factor group B1 [Source:NCBI gene (formerly Entrezgene);Acc:842855] identity=68.8; qcov=0.927; evalue=0; confidence=high
Rice	`Os05g0494900` - identity=72.1; qcov=0.137; evalue=2.15e-95; confidence=weak
GO	GO:0003677 (DNA binding); GO:0006368 (transcription elongation by RNA polymerase II); GO:0008023 (transcription elongation factor complex); GO:0031491 (nucleosome binding); GO:0032968 (positive regulation of transcription elongation by RNA polymerase II); GO:0034728 (nucleosome organization); GO:0042393 (histone binding); GO:0042789 (mRNA transcription by RNA polymerase II); GO:0140673 (transcription elongation-coupled chromatin remodeling)
KEGG	-
Pfam	PF14632 (SPT6_acidic); PF14633 (SH2_2); PF14635 (HHH_7); PF14639 (YqgF); PF14641 (HTH_44); PF17674 (HHH_9); PF21710 (Spt6_S1); PF22706 (Tex_central_region)
InterPro	-
eggNOG	-
NR	GeneID:131003102

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057785560.1`
2	Nucleoplasm	核质	1.00000	`XP_057785560.1`
3	Nuclear speckle	核斑点	0.20000	`XP_057785560.1`
4	Chromosome	染色体	0.00000	`XP_057785560.1`
5	Centromere	着丝粒	0.00000	`XP_057785560.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:63157794`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A11,B112,B31,B47,D1
`Chr1:63158054`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B110,B132,B139,C46,D6
`Chr1:63158550`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C27
`Chr1:63158828`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B2,C32
`Chr1:63158853`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A11,B112
`Chr1:63159827`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A6,B7,B97,C83
`Chr1:63160385`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A18,B5
`Chr1:63160568`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B31,B47,D1
`Chr1:63161572`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B50,D11
`Chr1:63161647`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B139
`Chr1:63161870`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C5
`Chr1:63161876`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C64

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057785560.1

1625 aa

812

1625

SPT6_acidic

HTH_44

Tex_central_region

YqgF

HHH_7

HHH_9

Spt6_S1

SH2_2

PF14632 SPT6_acidic 36-125 aa PF14641 HTH_44 306-424 aa PF22706 Tex_central_region 533-702 aa PF14639 YqgF 736-893 aa PF14635 HHH_7 897-998 aa PF17674 HHH_9 1013-1100 aa PF21710 Spt6_S1 1112-1200 aa PF14633 SH2_2 1216-1432 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057785560.1`	Pfam	`PF14632`	SPT6_acidic	Family	36	125	6.2e-16	59.3	Acidic N-terminal SPT6
`XP_057785560.1`	Pfam	`PF14641`	HTH_44	Domain	306	424	7.9e-13	49.6	Helix-turn-helix DNA-binding domain of SPT6
`XP_057785560.1`	Pfam	`PF22706`	Tex_central_region	Domain	533	702	2.5e-07	31.6	Tex central region-like
`XP_057785560.1`	Pfam	`PF14639`	YqgF	Domain	736	893	1.2e-15	58.3	Holliday-junction resolvase-like of SPT6
`XP_057785560.1`	Pfam	`PF14635`	HHH_7	Domain	897	998	5.4e-20	72.4	Helix-hairpin-helix motif
`XP_057785560.1`	Pfam	`PF17674`	HHH_9	Domain	1013	1100	8.2e-07	30.5	HHH domain
`XP_057785560.1`	Pfam	`PF21710`	Spt6_S1	Domain	1112	1200	8.8e-09	36.3	Spt6, S1/OB domain
`XP_057785560.1`	Pfam	`PF14633`	SH2_2	Domain	1216	1432	1.1e-68	231.5	SH2 domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057929577.1
CTCATAATAATATATTTTAAAAAAACACAAACAAGTGCGCTTAACCCATACATATACACACAACACATATCACTCATATGCAAACACACACTGGGTGTGTGACTGTGTGTGATTGGTTCCTCCTTCTGTATATTGAGGAGTGAAAATCAGAGGGTTTCCGGCTTTCCGTGTACTAGGGTTTGCCACCAGTTTCATTTTCTCCACACTCACGGACAAATTGTGTCCGTAAATTATAACTACGCCGCTTCTAGGGTTTCGCC...

CDS

1 records

下载 CDS FASTA

LOC131003102
ATGGCTGGCAAAAATGTGATCTCCGACGATGACGATGAGATCGGAGTCGAAGAAGAAGAAGAAAGAGACGAGGAGCCTTATGGAGACCGAGGTGGTGATCGTGGCGATGACGATGAAGATGAAGAAGACGATGAGGAAGGACAGGATGAATATGAAAAAGATGGATTTATAGTGGACGATGTTGAGGACGAAGAGGACGAGGAAGAAGATCGAGTTGATAGCGATGAGGAGCAGAAGAAAAAGAAAAGAAAGAAAAGGGA...

Protein

1 records

下载 Protein FASTA

XP_057785560.1
MAGKNVISDDDDEIGVEEEEERDEEPYGDRGGDRGDDDEDEEDDEEGQDEYEKDGFIVDDVEDEEDEEEDRVDSDEEQKKKKRKKREQFMLDEDDYELLQESNISVNRPKLESKKFKRLKKARRDAEEEPSGFADEEEFDGSGKGGRTAEEKLKRSLFGDDDGQPLEDIAEEDEQLEEEEDADIGDEDEMADFIVDEEEVDEHGAPVRRKKPKKSRQRPGISSSALQEAHEIFGDVEDLLRLRKIDVRDRFGETSERSLE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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