Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004992`

染色体: Chr01 坐标: 67952208-67955835 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004992`
名称	SmilChr01G004992
描述	D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	67952208 - 67955835 / `+`

ID 对照

NCBI Gene ID	`LOC131005323`
GeneID	`131005323`
locus_tag	`-`
NCBI Name	`LOC131005323`
原始查询	`SmilChr01G004992`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like
产物	D-3-phosphoglycerate dehydrogenase 3%2C chloroplastic-like
Arabidopsis	`AT4G34200` (EDA9) D-3-phosphoglycerate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:829568] identity=80.5; qcov=0.97; evalue=0; confidence=high
Rice	`Os04g0650800` - identity=84.3; qcov=0.908; evalue=0; confidence=high
GO	GO:0004617 (phosphoglycerate dehydrogenase activity); GO:0006564 (L-serine biosynthetic process); GO:0009570 (chloroplast stroma); GO:0051287 (NAD binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00389 (2-Hacid_dh); PF01842 (ACT); PF02826 (2-Hacid_dh_C); PF07991 (KARI_N); PF19304 (PGDH_inter)
InterPro	-
eggNOG	-
NR	GeneID:131005323

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057788215.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057788215.1`
3	Nucleus	细胞核	0.00000	`XP_057788215.1`
4	Chromosome	染色体	0.00000	`XP_057788215.1`
5	Centromere	着丝粒	0.00000	`XP_057788215.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:67952362`	`A`	`AC`	1bp_insertion	frameshift_variant	2	A23,B24
`Chr1:67952362`	`A`	`AC`	1bp_insertion	CDS_variant	2	A23,B24
`Chr1:67952365`	`CG`	`C`	1bp_deletion	frameshift_variant	2	A23,B24
`Chr1:67952365`	`CG`	`C`	1bp_deletion	CDS_variant	2	A23,B24
`Chr1:67952393`	`TC`	`T`	1bp_deletion	frameshift_variant	1	B76
`Chr1:67952393`	`TC`	`T`	1bp_deletion	CDS_variant	1	B76
`Chr1:67952429`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B59
`Chr1:67952429`	`AC`	`A`	1bp_deletion	CDS_variant	1	B59
`Chr1:67952441`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C1,C43
`Chr1:67952512`	`GC`	`G`	1bp_deletion	frameshift_variant	1	C52
`Chr1:67952512`	`GC`	`G`	1bp_deletion	CDS_variant	1	C52
`Chr1:67952566`	`GC`	`G`	1bp_deletion	frameshift_variant	2	A1,C12

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788215.1

598 aa

299

598

2-Hacid_dh

2-Hacid_dh_C

KARI_N

PGDH_inter

ACT

PF00389 2-Hacid_dh 59-368 aa PF02826 2-Hacid_dh_C 161-336 aa PF07991 KARI_N 193-353 aa PF19304 PGDH_inter 379-485 aa PF01842 ACT 527-586 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788215.1`	Pfam	`PF00389`	2-Hacid_dh	Domain	59	368	2.2e-32	112.3	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
`XP_057788215.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	161	336	8.2e-64	214.9	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
`XP_057788215.1`	Pfam	`PF07991`	KARI_N	Family	193	353	3.3e-06	27.5	Acetohydroxy acid isomeroreductase, NADPH-binding domain
`XP_057788215.1`	Pfam	`PF19304`	PGDH_inter	Domain	379	485	3.2e-15	57.0	D-3-phosphoglycerate dehydrogenase intervening domain
`XP_057788215.1`	Pfam	`PF01842`	ACT	Domain	527	586	1.1e-08	35.4	ACT domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057932232.1
AGCATAACCCCCTGCTTCAGTGTGCAGAGCCGCACTCATCAGTCATCCCTCACACCCCCAGCCCATCTTAGCAAACACCACCATCCCCACACCGTTTCTGAAATGGCGGCGTCAGCTTCGTCGACAAGACCTCAAACTCTCGTCGCCGTCCACCACCCGCCTCATGGCTGCGCCAGCGCCCCCTCTCCGCCACGTTCGGCATCAGCAGCTCTCCCTCCGCCACACCGCGACCAGCCCCGCCGCTTCATAGTCCTCTCCAT...

CDS

1 records

下载 CDS FASTA

LOC131005323
ATGGCGGCGTCAGCTTCGTCGACAAGACCTCAAACTCTCGTCGCCGTCCACCACCCGCCTCATGGCTGCGCCAGCGCCCCCTCTCCGCCACGTTCGGCATCAGCAGCTCTCCCTCCGCCACACCGCGACCAGCCCCGCCGCTTCATAGTCCTCTCCATGGACGCGAAGCCGACGATTCTCGTGTCGGAGAAACTGGGAGAGGCGGTGAACCTCCTCAAGGAGTTCGCCAACGTCGATTGCTCGTACAACCTCAGCCCGAG...

Protein

1 records

下载 Protein FASTA

XP_057788215.1
MAASASSTRPQTLVAVHHPPHGCASAPSPPRSASAALPPPHRDQPRRFIVLSMDAKPTILVSEKLGEAGXNLLKEFANVDCSYNLSPRSSAPRFSLCDALIVRSGTKVNREVFESSAGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNIAQADASVKAGKWERNKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGVELVSFDEAISTADFISLHMPLT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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