Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G005048`

染色体: Chr01 坐标: 68404875-68418008 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G005048`
名称	SmilChr01G005048
描述	phosphatidylinositol 4-kinase alpha 1
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	68404875 - 68418008 / `-`

ID 对照

NCBI Gene ID	`LOC131005340`
GeneID	`131005340`
locus_tag	`-`
NCBI Name	`LOC131005340`
原始查询	`SmilChr01G005048`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	phosphatidylinositol 4-kinase alpha 1
产物	phosphatidylinositol 4-kinase alpha 1
Arabidopsis	`AT1G49340` (ATPI4K ALPHA) Phosphatidylinositol 3- and 4-kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:841357] identity=71.6; qcov=1.02; evalue=0; confidence=high
Rice	`Os03g0711200` - identity=81.5; qcov=0.295; evalue=0; confidence=weak
GO	GO:0004430 (1-phosphatidylinositol 4-kinase activity); GO:0005737 (cytoplasm); GO:0005886 (plasma membrane); GO:0046854 (phosphatidylinositol phosphate biosynthetic process); GO:0048015 (phosphatidylinositol-mediated signaling)
KEGG	smil00562 (Inositol phosphate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil04070 (Phosphatidylinositol signaling system - Salvia miltiorrhiza (redroot sage))
Pfam	PF00454 (PI3_PI4_kinase); PF00613 (PI3Ka); PF19274 (PI4K_N)
InterPro	-
eggNOG	-
NR	GeneID:131005340

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	0.80000	`XP_057788237.1`
2	Cytosol	细胞质基质	0.80000	`XP_057788237.1`
3	Nucleus	细胞核	0.20000	`XP_057788237.1`
4	Golgi apparatus	高尔基体	0.20000	`XP_057788237.1`
5	Chromosome	染色体	0.00000	`XP_057788237.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:68405470`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr1:68406478`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B52,B8,C37
`Chr1:68407453`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B90,B92
`Chr1:68408181`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C31
`Chr1:68409517`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr1:68409745`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B50
`Chr1:68409772`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A22,C31
`Chr1:68410635`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B125,B63,B90
`Chr1:68410680`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B123
`Chr1:68410680`	`AC`	`A`	1bp_deletion	CDS_variant	1	B123
`Chr1:68410863`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C33
`Chr1:68412236`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C33

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788237.1

2029 aa

1014

2029

PI4K_N

PI3Ka

PI3_PI4_kinase

PF19274 PI4K_N 265-909 aa PF19274 PI4K_N 936-1467 aa PF00613 PI3Ka 1507-1634 aa PF00454 PI3_PI4_kinase 1769-1976 aa

XP_057788238.1

1999 aa

1000

1999

PI4K_N

PI3Ka

PI3_PI4_kinase

PF19274 PI4K_N 265-1437 aa PF00613 PI3Ka 1477-1604 aa PF00454 PI3_PI4_kinase 1739-1946 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788237.1`	Pfam	`PF19274`	PI4K_N	Repeat	265	909	0	2136.2	PI4-kinase N-terminal region
`XP_057788237.1`	Pfam	`PF19274`	PI4K_N	Repeat	936	1467	0	2136.2	PI4-kinase N-terminal region
`XP_057788237.1`	Pfam	`PF00613`	PI3Ka	Repeat	1507	1634	9e-22	78.1	Phosphoinositide 3-kinase family, accessory domain (PIK domain)
`XP_057788237.1`	Pfam	`PF00454`	PI3_PI4_kinase	Family	1769	1976	2e-36	126.9	Phosphatidylinositol 3- and 4-kinase
`XP_057788238.1`	Pfam	`PF19274`	PI4K_N	Repeat	265	1437	0	2160.0	PI4-kinase N-terminal region
`XP_057788238.1`	Pfam	`PF00613`	PI3Ka	Repeat	1477	1604	8.8e-22	78.2	Phosphoinositide 3-kinase family, accessory domain (PIK domain)
`XP_057788238.1`	Pfam	`PF00454`	PI3_PI4_kinase	Family	1739	1946	1.9e-36	126.9	Phosphatidylinositol 3- and 4-kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057932255.1
TAGAATTTGTTAACACAAAATTAATAAAAATTTCCGAAAATAAAAACAAGAAAAAAAGAAAAAGGCACAGACAAAAACAAAAAGATCTGAAAAAACGGAGGCGCGGTAATGTGTGCCCTCAACGCAGCACAAGTCGGGGCGAAGACGAAGAGCGACAGTCACCCTACGGCGCCGTTTCATCACCGGCATCGGTTCCCCCATCTCCGCTGCTGTTCATAAACCCTAATTTTGCCGGATTCCGTGCCGAAACTCGCCGCATT...

XM_057932254.1
TAGAATTTGTTAACACAAAATTAATAAAAATTTCCGAAAATAAAAACAAGAAAAAAAGAAAAAGGCACAGACAAAAACAAAAAGATCTGAAAAAACGGAGGCGCGGTAATGTGTGCCCTCAACGCAGCACAAGTCGGGGCGAAGACGAAGAGCGACAGTCACCCTACGGCGCCGTTTCATCACCGGCATCGGTTCCCCCATCTCCGCTGCTGTTCATAAACCCTAATTTTGCCGGATTCCGTGCCGAAACTCGCCGCATT...

CDS

2 records

下载 CDS FASTA

LOC131005340
ATGGAGTCGTTGGTGGAGCTCTGCGATTTAATCGCGCAGAATCCGGCTCAATTTCGTAATAAGATAGCGTGGATTTGCAGCCGCTGCCCGCCGGCGGAGTCGCTGATGATGGGATCGCCGACGGTTTCCAGGTCTCAACTCCATGCGATACTCGCGGTCGCGCGATTCCTCTCGAAATGCCCCAATTCGGAACACGAAACCCCCAAGTCGCTGATTCTCGCGTTTTACCGCTCAATTCCTTTGACCTTTAATCCCAAATT...

Protein

2 records

下载 Protein FASTA

XP_057788237.1
MESLVELCDLIAQNPAQFRNKIAWICSRCPPAESLMMGSPTVSRSQLHAILAVARFLSKCPNSEHETPKSLILAFYRSIPLTFNPKFWPQAFSPEAVSSFFNDFMSYISNAAELSPDFSTDVAGFTGEIVIQTITNADSSISRVFLNALCSNFPPIMLADANKLISVLLDRFDVGVPILSKDGILTPDAGSAQGSPLSGNYYQSPNVSADSSSSAASKDGIVANGGDSVSWKSNGDLSAAAAYKRNIKFFEDEPVESLEK...

XP_057788238.1
MESLVELCDLIAQNPAQFRNKIAWICSRCPPAESLMMGSPTVSRSQLHAILAVARFLSKCPNSEHETPKSLILAFYRSIPLTFNPKFWPQAFSPEAVSSFFNDFMSYISNAAELSPDFSTDVAGFTGEIVIQTITNADSSISRVFLNALCSNFPPIMLADANKLISVLLDRFDVGVPILSKDGILTPDAGSAQGSPLSGNYYQSPNVSADSSSSAASKDGIVANGGDSVSWKSNGDLSAAAAYKRNIKFFEDEPVESLEK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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