Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G005248`

染色体: Chr01 坐标: 70011555-70016026 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G005248`
名称	SmilChr01G005248
描述	TATA-box-binding protein 2
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	70011555 - 70016026 / `+`

ID 对照

NCBI Gene ID	`LOC131005583`
GeneID	`131005583`
locus_tag	`-`
NCBI Name	`LOC131005583`
原始查询	`SmilChr01G005248`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	TATA-box-binding protein 2
产物	TATA-box-binding protein 2
Arabidopsis	`AT1G55520` (TBP2) TATA binding protein 2 [Source:NCBI gene (formerly Entrezgene);Acc:841999] identity=93; qcov=1; evalue=2.01e-137; confidence=high
Rice	`Os03g0657000` (OsTBP2) - identity=96.4; qcov=0.975; evalue=1.21e-141; confidence=high
GO	GO:0003677 (DNA binding); GO:0006352 (DNA-templated transcription initiation); GO:0016251 (RNA polymerase II general transcription initiation factor activity)
KEGG	smil03022 (Basal transcription factors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00352 (TBP)
InterPro	-
eggNOG	-
NR	GeneID:131005583

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057788573.1`
2	Cytoplasm	细胞质	1.00000	`XP_057788573.1`
3	Nucleoplasm	核质	1.00000	`XP_057788574.1`
4	Nucleolus	核仁	0.80000	`XP_057788574.1`
5	Cytosol	细胞质基质	0.60000	`XP_057788573.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:70013237`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B69
`Chr1:70013254`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B82,B92
`Chr1:70013291`	`GC`	`G`	1bp_deletion	frameshift_variant	38	A14,A19,A9,B10,B117,B127,B18,B28,B35,B38,B42,B43,B48,B5,B51,B55,B6,B68,B69,B82,B88,B94,C18,C22,C29,C32,C34,C43,C54,C61,C67,C81,C82,C87,D11,D3,D5,D8
`Chr1:70013582`	`C`	`T`	EMS_canonical_SNV	stop_gained	7	B10,B119,B60,B70,B91,C12,C43
`Chr1:70014320`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B123,B17,C1,D4
`Chr1:70014322`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B17,D4
`Chr1:70014353`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C3,D1,D10
`Chr1:70015339`	`T`	`TTG`	2bp_insertion	frameshift_variant	68	A15,A16,A20,A22,A9,B105,B108,B110,B111,B117,B123,B129,B133,B137,B18,B20,B22,B23,B25,B33,B35,B38,B41,B47,B49,B51,B52,B57,B58,B6,B61,B62,B67,B68,B69,B70,B74,B75,B80,B88,B94,B97,C12,C18,C19,C20,C30,C32,C42,C44,C51,C54,C6,C63,C65,C67,C71,C72,C74,C78,C80,C9,D1,D11,D2,D3,D5,D7
`Chr1:70015352`	`T`	`TA`	1bp_insertion	frameshift_variant	71	A15,A16,A20,A22,A9,B105,B108,B110,B111,B117,B123,B129,B133,B137,B14,B16,B18,B20,B22,B23,B25,B33,B35,B38,B41,B47,B49,B51,B52,B57,B58,B6,B61,B62,B67,B68,B69,B70,B74,B75,B80,B88,B94,B97,C12,C18,C19,C20,C30,C32,C42,C44,C51,C54,C55,C6,C63,C65,C67,C71,C72,C74,C78,C80,C9,D1,D11,D2,D3,D5,D7
`Chr1:70015406`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C26
`Chr1:70015418`	`A`	`AG`	1bp_insertion	frameshift_variant	1	C26
`Chr1:70015418`	`A`	`AG`	1bp_insertion	CDS_variant	1	C26

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788573.1

252 aa

126

252

TBP

PF00352 TBP 24-105 aa PF00352 TBP 113-196 aa

XP_057788574.1

201 aa

100

201

TBP

PF00352 TBP 24-105 aa PF00352 TBP 113-196 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788573.1`	Pfam	`PF00352`	TBP	Domain	24	105	1.5e-69	230.6	Transcription factor TFIID (or TATA-binding protein, TBP)
`XP_057788573.1`	Pfam	`PF00352`	TBP	Domain	113	196	1.5e-69	230.6	Transcription factor TFIID (or TATA-binding protein, TBP)
`XP_057788574.1`	Pfam	`PF00352`	TBP	Domain	24	105	6e-70	231.8	Transcription factor TFIID (or TATA-binding protein, TBP)
`XP_057788574.1`	Pfam	`PF00352`	TBP	Domain	113	196	6e-70	231.8	Transcription factor TFIID (or TATA-binding protein, TBP)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057932591.1
CATCAGCCCTCCAGATCCATAAGCTGTAGCCATCCCCTCTTTTCCCCACAGACATCGCAAACTCCCTTTCTTCTCTCTCCCTCTCTATAAACCTCGTCAATTGCGTATATATATAAGAGCGATCATATAAAAGACTCCTCCTTTCGAATTCTTACCGCTCTTATTCCAAATCATCTCTCGTGTTTCCTCGTCTCTCATCATCTGCTCAGCAACGACTGTATAAAAAACCCTAGATCATTCCTATTCACACCTTCAAGTAT...

XM_057932590.1
GATCCATAAGCTGTAGCCATCCCCTCTTTTCCCCACAGACATCGCAAACTCCCTTTCTTCTCTCTCCCTCTCTATAAACCTCGTCAATTGCGTATATATATAAGAGCGATCATATAAAAGACTCCTCCTTTCGAATTCTTACCGCTCTTATTCCAAATCATCTCTCGTGTTTCCTCGTCTCTCATCATCTGCTCAGCAACGACTGTATAAAAAACCCTAGATCATTCCTATTCACACCTTCAAGTATTGTGGAAGTTGGT...

CDS

2 records

下载 CDS FASTA

LOC131005583
ATGGCAGATCCTCAAGGTATGGAAGGGATCCAACCAGTTGATCTCTCCAAGCATCCCTCCGGAATTGTTCCAACTCTCCAGAATATTGTCTCGACAGTCAATTTGGACTGCAAATTAGATCTTAAAGCTATAGCATTGCAGGCTCGTAATGCAGAATACAATCCCAAGCGTTTTGCTGCTGTGATTATGAGGATTCGAGAACCAAAAACAACAGCACTAATATTTGCATCTGGAAAGATGGTGTGTACAGGAGCCAAGAG...

Protein

2 records

下载 Protein FASTA

XP_057788573.1
MADPQGMEGIQPVDLSKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEQQSKLAARKYARIIQKLGFPAKFKDFKIQNIVGSCDVKFPIRLEGLAYAHGAFSSYEPELFPGLIYRMKQPKIVLLIFVSGKIVLTGAKVRDETYTAFENIYPVLTEFRKVQQWYDHDGVVCFNFYYYIGDFAFITSMNGFMCALGAPPVHMSLTLDPLTGKLL

XP_057788574.1
MADPQGMEGIQPVDLSKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEQQSKLAARKYARIIQKLGFPAKFKDFKIQNIVGSCDVKFPIRLEGLAYAHGAFSSYEPELFPGLIYRMKQPKIVLLIFVSGKIVLTGAKVRDETYTAFENIYPVLTEFRKVQQ

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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