Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G005748`

染色体: Chr01 坐标: 73560705-73564959 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G005748`
名称	SmilChr01G005748
描述	DNA excision repair protein ERCC-1-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	73560705 - 73564959 / `+`

ID 对照

NCBI Gene ID	`LOC131005935`
GeneID	`131005935`
locus_tag	`-`
NCBI Name	`LOC131005935`
原始查询	`SmilChr01G005748`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA excision repair protein ERCC-1-like
产物	DNA excision repair protein ERCC-1-like
Arabidopsis	`AT3G05210` (ERCC1) nucleotide repair protein [Source:NCBI gene (formerly Entrezgene);Acc:819685] identity=65.8; qcov=0.94; evalue=2.44e-162; confidence=high
Rice	`Os10g0518900` (ERCC1) - identity=70.7; qcov=0.681; evalue=5.45e-136; confidence=high
GO	GO:0000110 (nucleotide-excision repair factor 1 complex); GO:0000710 (meiotic mismatch repair); GO:0003684 (damaged DNA binding); GO:0003697 (single-stranded DNA binding); GO:0005634 (nucleus); GO:0006289 (nucleotide-excision repair); GO:0006312 (mitotic recombination); GO:0070522 (ERCC4-ERCC1 complex); GO:0070914 (UV-damage excision repair)
KEGG	smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage)); smil03460 (Fanconi anemia pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF03834 (Rad10); PF12826 (HHH_2); PF14520 (HHH_5)
InterPro	-
eggNOG	-
NR	GeneID:131005935

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057789038.1`
2	Nucleoplasm	核质	1.00000	`XP_057789038.1`
3	Nuclear body	核内小体	0.80000	`XP_057789038.1`
4	Chromosome	染色体	0.00000	`XP_057789038.1`
5	Centromere	着丝粒	0.00000	`XP_057789038.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:73561174`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A3,B103,B43,C84
`Chr1:73561179`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C62
`Chr1:73561270`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A3,C84
`Chr1:73561298`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B118,B123,B45,B54,C62
`Chr1:73561310`	`T`	`TC`	1bp_insertion	frameshift_variant	14	A10,A20,B122,B36,B4,B52,B62,B8,B90,B92,C24,C49,C64,C66
`Chr1:73561325`	`T`	`TC`	1bp_insertion	frameshift_variant	14	A10,A20,B122,B36,B4,B52,B62,B8,B90,B92,C24,C49,C64,C66
`Chr1:73561327`	`A`	`AGC`	2bp_insertion	frameshift_variant	14	A10,A20,B122,B36,B4,B52,B62,B8,B90,B92,C24,C49,C64,C66
`Chr1:73563136`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B20,C44
`Chr1:73563208`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B20
`Chr1:73563350`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A23,B43
`Chr1:73563359`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C50
`Chr1:73563690`	`TCA`	`T`	2bp_deletion	frameshift_variant	1	B23

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057789038.1

386 aa

193

386

Rad10

HHH_5

HHH_2

PF03834 Rad10 103-223 aa PF14520 HHH_5 242-293 aa PF12826 HHH_2 245-299 aa

XP_057789039.1

386 aa

193

386

Rad10

HHH_5

HHH_2

PF03834 Rad10 103-223 aa PF14520 HHH_5 242-293 aa PF12826 HHH_2 245-299 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057789038.1`	Pfam	`PF03834`	Rad10	Domain	103	223	4.7e-50	169.1	Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
`XP_057789038.1`	Pfam	`PF14520`	HHH_5	Domain	242	293	7.7e-08	33.4	SAM-like Helix-hairpin-helix tandem
`XP_057789038.1`	Pfam	`PF12826`	HHH_2	Motif	245	299	1.4e-06	29.1	Helix-hairpin-helix motif
`XP_057789039.1`	Pfam	`PF03834`	Rad10	Domain	103	223	4.7e-50	169.1	Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
`XP_057789039.1`	Pfam	`PF14520`	HHH_5	Domain	242	293	7.7e-08	33.4	SAM-like Helix-hairpin-helix tandem
`XP_057789039.1`	Pfam	`PF12826`	HHH_2	Motif	245	299	1.4e-06	29.1	Helix-hairpin-helix motif

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057933056.1
AAGTTGGAAGAGTTTTACAGTTAATATTTAATATTGTTTCTCCCAATTCTCTCCTTGACCGCGTTTCTCCGCCGCCGTCTGGAGCATCGGTAAGCAAGCCGCCGCCGCCGCAGTGCGCATCATCCGTTCCGGCTAAATTGTTCCGCCATCACTTCTGCTCTTCCATTGAGGAAGTAGAAAGGAGGGATTTTGGAAAGGTGAATTAGGAGAGTGAGTTGTGAAGATGGAAAACAGAGGTGATCCTGAGCAGCAGAAACAGA...

XM_057933055.1
CAGTTAATATTTAATATTGTTTCTCCCAATTCTCTCCTTGACCGCGTTTCTCCGCCGCCGTCTGGAGCATCGGTAAGCAAGCCGCCGCCGCCGCAGTGCGCATCATCCGTTCCGGCTAAATTGTTCCGCCATCACTTCTGCTCTTCCATTGAGAAAGGAGGGATTTTGGAAAGGTGAATTAGGAGAGTGAGTTGTGAAGATGGAAAACAGAGGTGATCCTGAGCAGCAGAAACAGAATAATGCATCATTTGTTGTGAAAA...

CDS

2 records

下载 CDS FASTA

LOC131005935
ATGGAAAACAGAGGTGATCCTGAGCAGCAGAAACAGAATAATGCATCATTTGTTGTGAAAATACCTTCATATGAAGAGGTGGTTGAGAGCTCCCAACCTAAGTCGCAATCTTTATTCAAGCCTTCCTCCTCCTTTTCGCAAGCTTTCAATTTTATCAAAAACACTGAATTTTACACCACCCCGCCATCTGTACCGGTGGCCCAGTCCTCCAAAGATGCCCCTTCATCCTCTCAAGGATCTTATCCAAGGCAAACCATTCA...

Protein

2 records

下载 Protein FASTA

XP_057789038.1
MENRGDPEQQKQNNASFVVKIPSYEEVVESSQPKSQSLFKPSSSFSQAFNFIKNTEFYTTPPSVPVAQSSKDAPSSSQGSYPRQTIQSEAPSTSVSSAGANRNAIIVSHRQKGNPLLKHIRNVRWVFADVVCDYLLGQNACALYLSLRYHLLHPDYLYFRIRELQKNFKLRIVLCHVDVEDVVKPLLEVTKTALLHDCTLLCAWSLEECGRYLETIKVYENKPADLIQGQMDMDYISRLNHALTSIRHVNKTDVVTLGST...

XP_057789039.1
MENRGDPEQQKQNNASFVVKIPSYEEVVESSQPKSQSLFKPSSSFSQAFNFIKNTEFYTTPPSVPVAQSSKDAPSSSQGSYPRQTIQSEAPSTSVSSAGANRNAIIVSHRQKGNPLLKHIRNVRWVFADVVCDYLLGQNACALYLSLRYHLLHPDYLYFRIRELQKNFKLRIVLCHVDVEDVVKPLLEVTKTALLHDCTLLCAWSLEECGRYLETIKVYENKPADLIQGQMDMDYISRLNHALTSIRHVNKTDVVTLGST...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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