Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G005924`

染色体: Chr01 坐标: 75045950-75047871 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G005924`
名称	SmilChr01G005924
描述	probable E3 ubiquitin-protein ligase ARI8
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	75045950 - 75047871 / `+`

ID 对照

NCBI Gene ID	`LOC131006201`
GeneID	`131006201`
locus_tag	`-`
NCBI Name	`LOC131006201`
原始查询	`SmilChr01G005924`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable E3 ubiquitin-protein ligase ARI8
产物	probable E3 ubiquitin-protein ligase ARI8
Arabidopsis	`AT1G65430` (ARI8) IBR domain-containing protein [Source:NCBI gene (formerly Entrezgene);Acc:842854] identity=47.4; qcov=0.936; evalue=7.69e-159; confidence=high
Rice	`Os08g0540300` (P0666G10.134) - identity=42.5; qcov=1; evalue=3.67e-143; confidence=medium
GO	GO:0000151 (ubiquitin ligase complex); GO:0000209 (protein polyubiquitination); GO:0005737 (cytoplasm); GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0008270 (zinc ion binding); GO:0031624 (ubiquitin conjugating enzyme binding); GO:0032436 (positive regulation of proteasomal ubiquitin-dependent protein catabolic process); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF01485 (IBR); PF13923 (zf-C3HC4_2); PF19422 (Ariadne); PF22191 (IBR_1); PF22605 (IBR_2)
InterPro	-
eggNOG	-
NR	GeneID:131006201

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057789363.1`
2	Chromosome	染色体	0.00000	`XP_057789363.1`
3	Centromere	着丝粒	0.00000	`XP_057789363.1`
4	Chromatin	染色质	0.00000	`XP_057789363.1`
5	Telomere	端粒	0.00000	`XP_057789363.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:75046097`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B78,C76
`Chr1:75046123`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr1:75046139`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B88
`Chr1:75046152`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	C19,C28,C63,C75
`Chr1:75046247`	`GT`	`G`	1bp_deletion	frameshift_variant	13	A6,B140,B24,B39,B41,B62,C31,C42,C52,C67,C84,D6,D9
`Chr1:75046289`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C63,C75
`Chr1:75046301`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C63,C75
`Chr1:75046307`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C63,D10
`Chr1:75046309`	`G`	`GC`	1bp_insertion	frameshift_variant	36	A1,A16,A4,B1,B108,B113,B120,B125,B134,B23,B36,B40,B46,B47,B52,B65,B66,B69,B77,C11,C19,C20,C28,C33,C62,C63,C65,C68,C69,C72,C78,C79,C83,C84,D10,D4
`Chr1:75046332`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B41,C42,C53,C75
`Chr1:75046345`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C6
`Chr1:75046378`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C76

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057789363.1

534 aa

267

534

zf-C3HC4_2

zf-C3HC4

IBR

IBR_2

IBR_1

Ariadne

PF13923 zf-C3HC4_2 108-138 aa PF00097 zf-C3HC4 108-143 aa PF01485 IBR 177-241 aa PF22605 IBR_2 264-300 aa PF22191 IBR_1 265-301 aa PF19422 Ariadne 332-476 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057789363.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	108	138	1.8e-06	28.3	Zinc finger, C3HC4 type (RING finger)
`XP_057789363.1`	Pfam	`PF00097`	zf-C3HC4	Domain	108	143	0.0002	21.9	Zinc finger, C3HC4 type (RING finger)
`XP_057789363.1`	Pfam	`PF01485`	IBR	Domain	177	241	5e-20	72.1	IBR domain, a half RING-finger domain
`XP_057789363.1`	Pfam	`PF22605`	IBR_2	Domain	264	300	2.3e-08	34.8	IBR domain
`XP_057789363.1`	Pfam	`PF22191`	IBR_1	Domain	265	301	3.1e-09	37.3	IBR domain
`XP_057789363.1`	Pfam	`PF19422`	Ariadne	Domain	332	476	5e-11	43.6	Ariadne domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057933380.1
CGCCAAAGATTCCATGGATTCTGAAGGCGAGGGTTTCTACAGCAGCAGTAGTGATACGGCGGCGGATGACAGCTTCGCTGATTACGCCGCCGTCAGCCGCCGCCAGAAACCCTACAAAATCCTAACAGAGGGCGACATCCAGCAACTCCTCGATGACGATATCTCCACAGTTTCCGACGTTCTCTCCGTCTCGAGAGGCGCCGCCTGCACCTTCCTCTGCCAGAATAATTGGAATCTCAGCTCCGTCTACGACAAATTTT...

CDS

1 records

下载 CDS FASTA

LOC131006201
ATGGATTCTGAAGGCGAGGGTTTCTACAGCAGCAGTAGTGATACGGCGGCGGATGACAGCTTCGCTGATTACGCCGCCGTCAGCCGCCGCCAGAAACCCTACAAAATCCTAACAGAGGGCGACATCCAGCAACTCCTCGATGACGATATCTCCACAGTTTCCGACGTTCTCTCCGTCTCGAGAGGCGCCGCCTGCACCTTCCTCTGCCAGAATAATTGGAATCTCAGCTCCGTCTACGACAAATTTTTCGCCACCGACGA...

Protein

1 records

下载 Protein FASTA

XP_057789363.1
MDSEGEGFYSSSSDTAADDSFADYAAVSRRQKPYKILTEGDIQQLLDDDISTVSDVLSVSRGAACTFLCQNNWNLSSVYDKFFATDDRNHQTAASSSSSQRELGQNLCKICYDEISPQNTVSAACGHPFCADCWKTYVAAAIDDGAGCLTLRCPEPGCGVAVGVDLIESLASTDGKEKYHRYLRQSYVEASRRREWCPAPGCNFAVEFDGGGGGGGYDVTCGCSHKFCWNCGEEHHRPVGCETVASWSEKNNSEAENTQW...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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