Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G006086`

染色体: Chr01 坐标: 76343863-76347883 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G006086`
名称	SmilChr01G006086
描述	DNA excision repair protein ERCC-1-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	76343863 - 76347883 / `+`

ID 对照

NCBI Gene ID	`LOC131006328`
GeneID	`131006328`
locus_tag	`-`
NCBI Name	`LOC131006328`
原始查询	`SmilChr01G006086`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA excision repair protein ERCC-1-like
产物	DNA excision repair protein ERCC-1-like
Arabidopsis	`AT3G05210` (ERCC1) nucleotide repair protein [Source:NCBI gene (formerly Entrezgene);Acc:819685] identity=65.9; qcov=0.883; evalue=3.38e-158; confidence=high
Rice	`Os10g0518900` (ERCC1) - identity=60; qcov=0.856; evalue=4.36e-131; confidence=high
GO	GO:0000110 (nucleotide-excision repair factor 1 complex); GO:0000710 (meiotic mismatch repair); GO:0003684 (damaged DNA binding); GO:0003697 (single-stranded DNA binding); GO:0005634 (nucleus); GO:0006289 (nucleotide-excision repair); GO:0006312 (mitotic recombination); GO:0070522 (ERCC4-ERCC1 complex); GO:0070914 (UV-damage excision repair)
KEGG	smil03420 (Nucleotide excision repair - Salvia miltiorrhiza (redroot sage)); smil03460 (Fanconi anemia pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF03834 (Rad10); PF12826 (HHH_2); PF14520 (HHH_5)
InterPro	-
eggNOG	-
NR	GeneID:131006328

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057789521.1`
2	Nuclear body	核内小体	1.00000	`XP_057789521.1`
3	Nucleoplasm	核质	1.00000	`XP_057789521.1`
4	Chromosome	染色体	0.00000	`XP_057789521.1`
5	Centromere	着丝粒	0.00000	`XP_057789521.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:76344316`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B71
`Chr1:76344435`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C70,C83
`Chr1:76344499`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	B101
`Chr1:76344499`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B101
`Chr1:76344521`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B88
`Chr1:76344688`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B22,B82,C2
`Chr1:76344689`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B35,B39,C69
`Chr1:76345160`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B21,B41,C52
`Chr1:76345177`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B34,C43
`Chr1:76345205`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D4
`Chr1:76346341`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A14,B60
`Chr1:76346897`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A10,A2,B122,B68,C31

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057789521.1

417 aa

208

417

Rad10

HHH_5

HHH_2

PF03834 Rad10 103-231 aa PF14520 HHH_5 250-301 aa PF12826 HHH_2 253-307 aa

XP_057789522.1

409 aa

204

409

Rad10

HHH_5

HHH_2

PF03834 Rad10 103-223 aa PF14520 HHH_5 242-293 aa PF12826 HHH_2 245-299 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057789521.1`	Pfam	`PF03834`	Rad10	Domain	103	231	4.8e-47	159.4	Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
`XP_057789521.1`	Pfam	`PF14520`	HHH_5	Domain	250	301	8.8e-08	33.2	SAM-like Helix-hairpin-helix tandem
`XP_057789521.1`	Pfam	`PF12826`	HHH_2	Motif	253	307	1.5e-06	28.9	Helix-hairpin-helix motif
`XP_057789522.1`	Pfam	`PF03834`	Rad10	Domain	103	223	5.8e-50	168.8	Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
`XP_057789522.1`	Pfam	`PF14520`	HHH_5	Domain	242	293	8.6e-08	33.3	SAM-like Helix-hairpin-helix tandem
`XP_057789522.1`	Pfam	`PF12826`	HHH_2	Motif	245	299	1.5e-06	29.0	Helix-hairpin-helix motif

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057933538.1
CCCAATTCTCTCCTTGGCCGCGTTTCTCCGCCGCCGTCTGGAGCATCGGTAAGCAAGCCGCCGCCGCCGCCGCCGCTGTGCGCATCATCCGTTCCGGCTAAATTGTTCCGCCATCACTTCTGCTCTTCCATTCGAGGAAGTAGAAAGGAGGGATTTTGGAAGGGTGAATTAGGAGAGTGAGTTGTGAAGATGGAAAACAGAGGTGATCCTGAGCAGCAGAGACAGAATAATGCATCATTTGTTGTGAAAATACCTTCATA...

XM_057933539.1
CCCAATTCTCTCCTTGGCCGCGTTTCTCCGCCGCCGTCTGGAGCATCGGTAAGCAAGCCGCCGCCGCCGCCGCCGCTGTGCGCATCATCCGTTCCGGCTAAATTGTTCCGCCATCACTTCTGCTCTTCCATTCGAGGAAGTAGAAAGGAGGGATTTTGGAAGGGTGAATTAGGAGAGTGAGTTGTGAAGATGGAAAACAGAGGTGATCCTGAGCAGCAGAGACAGAATAATGCATCATTTGTTGTGAAAATACCTTCATA...

CDS

2 records

下载 CDS FASTA

LOC131006328
ATGGAAAACAGAGGTGATCCTGAGCAGCAGAGACAGAATAATGCATCATTTGTTGTGAAAATACCTTCATATGAAGAGGTGGTTGAGAGCTCCCAACCTAACTCTCAATCTTTATTCAAGCCTTCCTCCTCCTTTTCGCAAGCTTTCAATTTTATCAAAAACACTGAATTTTACACCACCCCGCCATCTGTACCGGTGGCTCAGTCCTCCAAAGATGCCCCTTCATCCTCTCAAGGATCTTATCCAAGGCAAACCATTCA...

Protein

2 records

下载 Protein FASTA

XP_057789521.1
MENRGDPEQQRQNNASFVVKIPSYEEVVESSQPNSQSLFKPSSSFSQAFNFIKNTEFYTTPPSVPVAQSSKDAPSSSQGSYPRQTIQSEAPSTSVSSAGANRNAIIVSHRQKGNPLLKHIRNVRWVFADVVCDYLLGQNACALYLRIYSVVFFSLRYHLLHPDYLYFRIRELQKNFKLRVVLCHVDVEDVVKPLLEVTKTALLHDCTLLCAWSLEECGRYLETIKVYENKPADLIQGQMDMDYISRLNHALTSIRHVNKT...

XP_057789522.1
MENRGDPEQQRQNNASFVVKIPSYEEVVESSQPNSQSLFKPSSSFSQAFNFIKNTEFYTTPPSVPVAQSSKDAPSSSQGSYPRQTIQSEAPSTSVSSAGANRNAIIVSHRQKGNPLLKHIRNVRWVFADVVCDYLLGQNACALYLSLRYHLLHPDYLYFRIRELQKNFKLRVVLCHVDVEDVVKPLLEVTKTALLHDCTLLCAWSLEECGRYLETIKVYENKPADLIQGQMDMDYISRLNHALTSIRHVNKTDVVTLGST...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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