Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G000758`

染色体: Chr02 坐标: 12353795-12361407 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G000758`
名称	SmilChr02G000758
描述	E3 ubiquitin-protein ligase COP1-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	12353795 - 12361407 / `+`

ID 对照

NCBI Gene ID	`LOC131011238`
GeneID	`131011238`
locus_tag	`-`
NCBI Name	`LOC131011238`
原始查询	`SmilChr02G000758`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase COP1-like
产物	E3 ubiquitin-protein ligase COP1-like
Arabidopsis	`AT2G32950` (COP1) Transducin/WD40 repeat-like superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:817857] identity=71.4; qcov=0.947; evalue=0; confidence=high
Rice	`Os02g0771100` (PPS) - identity=68; qcov=1.02; evalue=0; confidence=high
GO	GO:0005515 (protein binding); GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process); GO:0061630 (ubiquitin protein ligase activity)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage)); smil04712 (Circadian rhythm - plant - Salvia miltiorrhiza (redroot sage))
Pfam	PF00097 (zf-C3HC4); PF00400 (WD40); PF13923 (zf-C3HC4_2); PF23098 (Beta-prop_NOL10_N)
InterPro	-
eggNOG	-
NR	GeneID:131011238

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	0.80000	`XP_057795011.1`
2	Nucleoplasm	核质	0.40000	`XP_057795011.1`
3	Cytoplasm	细胞质	0.40000	`XP_057795011.1`
4	Cytosol	细胞质基质	0.40000	`XP_057795011.1`
5	Cytoplasmic vesicle	细胞质囊泡	0.20000	`XP_057795011.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:12354112`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B1
`Chr2:12354178`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr2:12354278`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D3
`Chr2:12355379`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C42
`Chr2:12357046`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:12357779`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr2:12358577`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A16,C30
`Chr2:12359075`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A25,B3,B84,C29,C63
`Chr2:12361114`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C38

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795011.1

675 aa

338

675

zf-C3HC4

zf-C3HC4_2

WD40

Beta-prop_NOL10_N

WD40

PF00097 zf-C3HC4 49-86 aa PF13923 zf-C3HC4_2 49-86 aa PF00400 WD40 455-491 aa PF23098 Beta-prop_NOL10_N 468-641 aa PF00400 WD40 540-576 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795011.1`	Pfam	`PF00097`	zf-C3HC4	Domain	49	86	1.6e-08	35.0	Zinc finger, C3HC4 type (RING finger)
`XP_057795011.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	49	86	1.4e-10	41.5	Zinc finger, C3HC4 type (RING finger)
`XP_057795011.1`	Pfam	`PF00400`	WD40	Repeat	455	491	1.7e-28	98.5	WD domain, G-beta repeat
`XP_057795011.1`	Pfam	`PF23098`	Beta-prop_NOL10_N	Repeat	468	641	2.6e-09	37.4	Nucleolar protein 10-like, N-terminal domain
`XP_057795011.1`	Pfam	`PF00400`	WD40	Repeat	540	576	1.7e-28	98.5	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057939028.1
AAATTGAAAGCCCGCGTAACGTGGTGAATTTCCACCCATAGAAATCTCCCCTGCCGCTCTCGCACACACACACACACAAGTAACGTCCTCCTCTCCTTTCTTCACTCCTACGGAAAACGCCTCCACGCAGACGCGCGAGCCACCGCACAATTCACGCATGCATCTGTAGACCTGCCAGAATAAGCAGATTTCGAGCAGAATGGGCGGCCAGAGCACTTCAATCGGCGCTCTGGTGCCCACTGTGAAGTCCGAGCAGGCGG...

CDS

1 records

下载 CDS FASTA

LOC131011238
ATGGGCGGCCAGAGCACTTCAATCGGCGCTCTGGTGCCCACTGTGAAGTCCGAGCAGGCGGAAGAGGCTCCCGTGGCTCCGCCGTCGACTTCGACGGCGCCGGAGAAGGATCGGGGGGCGGAGGAGGCGGAGAAAGACATTCTGTGCCCGATATGCATGCAGATTATCAAGGATGCCTTTCTGACGGCGTGCGGACATAGTTTTTGCTACATGTGTATCGTGACGCATCTGCAGAACAAGAGTGACTGTCCGTGTTGCTC...

Protein

1 records

下载 Protein FASTA

XP_057795011.1
MGGQSTSIGALVPTVKSEQAEEAPVAPPSTSTAPEKDRGAEEAEKDILCPICMQIIKDAFLTACGHSFCYMCIVTHLQNKSDCPCCSQFLTKTHLYPNFLLNKLLAKTSARQIAKTSTPLEQLRQALEQGCETSVKDLESLLHVIVEKKKKMEQEEAETNMQILLDFLVFLKKKKLDELNEIQSDLQYIKQDIHAVEKRRIELYHRRDRYSAKMRMLSDDPNSKSLWPLLMDKHRDATTVSRITAPDQVRLSSSVSKNQK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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